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#strain

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Angstrom Minerals

Over 75% of people report feeling #stress that negatively affects their #physicalhealth. When the body is under that kind of #strain, #corticosteroids flood the system and lower #lymphocyte levels. When stress is #chronic, it affects all aspects of life, including #sleep and #diet. Managing stress through mindful #meditation and practices like #yoga protects the #immunesystem by stemming the levels of #cortisol and reducing the risk of #inflammation.

Public
KiwiNikki

1news.co.nz/2024/09/26/i-got-a

Ten days feeling sick you say? Flu is well-known for being a week. The latest strain of covid that has similar symptoms to flu - that taken 10 days. And causes high temperatures. And hospitalises people.

And with no free #rattests happening, chances are most people aren’t testing.

We are going to get walloped by the #strain causing havoc in UK/USA. But it won’t be #Covid. Of course not - because no one is #testing! Hayfever, summer cold, late flu…

1News · I got a flu jab this year – so why did the flu still knock me out?By Anna Murray
Public
Giuseppe Michieli

#Birdflu case in #Missouri was similar to #strain circulating in #cattle, CDC says, edition.cnn.com/2024/09/13/hea

Further information posted about Missouri case Friday in #CDC’s weekly #FluView report revealed that a close #household #contact of infected person got sick same day, had similar #symptoms but was never tested. Both people have since recovered. Simultaneous development of symptoms does not support person-to-person spread but suggests a common exposure, according to the CDC.

Public
Giuseppe Michieli

Identification of a #Orthohantavirus #strain by clinical #metagenomics in #Brazil pubmed.ncbi.nlm.nih.gov/391807

Reverse transcriptase polymerase chain reaction (RT-PCR) tests for #Dengue, #Zika, and #Chikungunya resulted negative. We were able to recover complete S, L, and M segments of virus in the Orthohantavirus genome.

PubMedIdentification of a Orthohantavirus strain by clinical metagenomics in Brazil - PubMedWe describe a case of a 33-year-old male presented with fever, myalgia, nausea, and asthenia for six days. The patient lived in a rural area. Initial hypotheses included arbovirus infection, viral hepatitis, and Lyme disease. Reverse transcriptase polymerase chain reaction (RT-PCR) tests for Dengue, …
Public
Giuseppe Michieli

#Genomic and #phenotypic characterization of an #Oropouche virus #strain implicated in the 2023-24 large-scale #outbreak in #Brazil biorxiv.org/cgi/content/short/

Our data shows that OROV can readily infect and replicate in non-human #primate #cells, supporting the role of non-human primates as important #reservoirs. Phylogenetic data supports a direct introduction of the same lineages causing the 2022-24 outbreak in Brazil from the #Amazonas state, the epicenter of the epidemics in Brazil.

Public
Giuseppe Michieli

Characterization of #Influenza D Virus #Reassortant #Strain in #Swine from Mixed #Pig and Beef #Farm, #France, Emerg Infect Dis.: wwwnc.cdc.gov/eid/article/30/8

Influenza D virus was isolated from pigs on a mixed pig and beef farm in France. Investigation suggested #bull-to-pig #transmission and spread among pigs. The swine influenza D virus recovered was a reassortant of D/660 and D/OK lineages. Reported #mutations in the #receptor binding site might be related to swine host adaptation.

Emerging Infectious Diseases journalCharacterization of Influenza D Virus Reassortant Strain in Swine from Mixed Pig and Beef Farm, FranceCharacterization of Influenza D Virus in Swine
Public
getmisch

Two & a half hours to see a doctor & grocery shop. And you wonder why New Yorkers are so tired. *Fifty-five minutes* before my vitals get taken at my clinic, then another fourty minutes (yes, I'm so old I spell fourty with a "U") to see a doctor.
#NYC #health #clinic #shared #doctor #nurse #practitioner #COVID #vaccine #no #go #will #wait for #new #strain in #September or #even #August #pointless #booster #shot #vitals #blood #pressure #NewYorkCity #NewYorkers #wait in #line #but #come #on

Public
Giuseppe Michieli

#Birdflu #strain in #US #cows shows minimal #air #spread in #ferret study {see also: mstdn.science/@GMIK69/11275170, Reuters: reuters.com/business/healthcar

LONDON, July 8 (Reuters) - The bird flu strain found in cows in the United States is not easily transmitted through the air among ferrets, a new study shows, although the scientist who led the work said it had shown some ability to spread this way. {Very limited ability.}

mstdn.scienceGiuseppe Michieli (@GMIK69@mstdn.science)#Pathogenicity and #transmissibility of #bovine #H5N1 #influenza virus, Nature: https://www.nature.com/articles/s41586-024-07766-6 Importantly, bovine HPAI H5N1 virus bound to #sialic acids expressed in #human upper #airways and inefficiently transmitted to exposed ferrets (one of four exposed ferrets seroconverted without virus detection). Bovine HPAI H5N1 virus thus possesses features that may facilitate #infection and #transmission in #mammals.
Public
Giuseppe Michieli

New #mpox #strain in #DRC 'most dangerous yet', bbc.com/news/articles/c2vv0pgg

A new strain of the mpox virus spreading quickly along the eastern border of Democratic Republic of Congo is "incredibly worrying", say health officials monitoring its spread.
The virus, which can cause #lesions across the whole body, is making some people very ill and can be deadly.

www.bbc.comNew mpox strain in DR Congo 'most dangerous yet'A current outbreak of the virus in the African country is "concerning", say health officials.
Public
Giuseppe Michieli

#H5N1 {#influenza} #strain of bird flu found in raw #milk from infected #animals: #WHO channelnewsasia.com/world/h5n1

GENEVA: The H5N1 bird flu virus strain has been detected in very high concentrations in raw milk from infected animals, the WHO said on Friday (Apr 19), though how long the virus can survive in milk is unknown.

CNAH5N1 strain of bird flu found in raw milk from infected animals: WHOGENEVA: The H5N1 bird flu virus strain has been detected in very high concentrations in raw milk from infected animals, the WHO said on Friday (Apr 19), though how long the virus can survive in milk is unknown. Avian influenza A (H5N1) first emerged in 1996 but since 2020, the number of outbreaks in birds
Public
Giuseppe Michieli

#Molecular characterization of the whole #genome of #H9N2 avian #influenza virus isolated from #Egyptian #poultry #farms, Arch Virol.: link.springer.com/article/10.1

...results show that the detected #strain had undergone intrasubtype #reassortment. Furthermore, it contains #changes in the viral #proteins that make it more likely to be #virulent, raising a question about the tendency of AIV H9N2 to become highly pathogenic in the future for both poultry and #humans.

SpringerLinkMolecular characterization of the whole genome of H9N2 avian influenza virus isolated from Egyptian poultry farms - Archives of VirologyH9N2 avian influenza viruses (AIVs) affect both poultry and humans on a global level, and they are especially prevalent in Egypt. In this study, we sequenced the entire genome of AIV H9N2 isolated from chickens in Egypt in 2021, using next-generation sequencing (NGS) technology. Phylogenetic analysis of the resulting sequences showed that the studied strain was generally monophyletic and grouped within the G1 sublineage of the Eurasian lineage. Four segments (polymerase basic 2 [PB2], polymerase basic 1 [PB1], polymerase acidic [PA], and non-structural [NS]) were related to Egyptian genotype II, while the nucleoprotein (NP), neuraminidase (NA), matrix (M), and haemagglutinin (HA) segments were related to Egyptian genotype I. Molecular analysis revealed that HA protein contained amino acid residues (191H and 234L) that suggested a predilection for attaching to human-like receptors. The antigenic sites of HA had two nonsynonymous mutations: V194I at antigenic site A and M40K at antigenic site B. Furthermore, the R403W and S372A mutations, which have been observed in H3N2 and H2N2 strains that caused human pandemics, were found in the NA protein of the detected strain. The internal proteins contained virulence markers: 504V in the PB2 protein, 622G, 436Y, 207K, and 677T in the PB1 protein, 127V, 550L, and 672L in PA protein, and 64F and 69P in the M protein. These results show that the detected strain had undergone intrasubtype reassortment. Furthermore, it contains changes in the viral proteins that make it more likely to be virulent, raising a question about the tendency of AIV H9N2 to become highly pathogenic in the future for both poultry and humans.
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