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#flagella

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David Ruffner

This reminds me...in grad school (~2013), I came across research about bacteria locomotion, and the bacteria have multiple flagella that form a bundle that twists together.

That was so confusing to me. I imagined them all twisted together, and then each flagellum trying to twist from its own motor. It seems like there would be a jam.

Now I came across two papers that help make sense of it. In both papers they created a scale model of how bacteria flagellum bundle. It seems that the multiple flagella rotate next to each other but do not actually tangle bu.edu/fluidlab/files/2016/01/ The second paper helped me to see it better. The helixes of the flagella line up and are in phase, so they effectively get out of each others way as they rotate. In the scale models it did jam if they were driven to hard, which messed with my intuition. pnas.org/doi/full/10.1073/pnas

#flagella
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Lukas VFN 🇪🇺

Follow the leader: A new study of #flagella in #algae reveals how they coordinate their movements to ensure cells steer efficiently elifesciences.org/digests/8610 #protists #microbes

The younger flagellum sets the beat for #Chlamydomonas reinhardtii elifesciences.org/articles/861

"To steer, C. reinhardtii adjusts the strength of the strokes made by each flagellum. Despite this asymmetry, the flagella must continue to beat in synchrony to move efficiently."

illustration of a single-celled green alga with 2 flagella
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Lukas VFN 🇪🇺

Flagellum, shift into reverse gear! schaechter.asmblog.org/schaech

Structural basis of directional switching by the bacterial flagellum pubmed.ncbi.nlm.nih.gov/384592

"In a manual gearbox, a gearwheel is inserted between the countershaft and the drive shaft. This reverses the rotation. #Flagella of E. coli, Salmonella #bacteria have found a smart solution to do without an additional wheel: they run their engine along the outside of a gearwheel or, if they reverse the direction of rotation, on its inside"

GIF
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Bernhard Schermer

📣 📣 📣 There are less than nine months remaining until Cilia2024, happening from September 10th to 13th in Dublin! 🇮🇪 :happy:

Remember to mark your calendars! What an amazing lineup of programs and speakers!

For more information, visit cilia2024.ie/

Registration opens in February.

@cilia @cellbiology @cellbio
#CellBiology #DevelopmentalBiology #DevBio #Nephrology #Ciliopathies #cilia #Science #Conference #RareDiseases #Kidney #Biology #Flagella #PCD #ADPKD #BBS #NPHP #CKD #PKD

Logo of the European Cilia Meeting 2024 in green letter with the i looking like green cilia with pink basal bodies and nine microtubule pairs forming a ring inside the a.
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Small Things Considered

The Hitchhiker's Guide to... Flagellar Tips

by Christoph
The same frontispiece twice within a few days at STC? No, not quite. It's not about Roberto's hitchhiking phage this time, or the flagellated bacterium, or the hitchhiking spore, but about the tip of the flagellum (black, left). Disclosure: already back in 2020, I talked with Alise, who created the image, and three other passionate science illustrators...

Read more → schaechter.asmblog.org/schaech

Image by Alise Muok (deatail)
#microbiology#flagella
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Eliza Wolfson

My #ThrowbackThursday #sciart continues!

Flagella origami - mixed media, 2016.

From the first year of #freelance #ScienceIllustration, I bring you the #StructuralBiology of bacterial #flagella filaments. This was commissioned as part of the branding for a flagella & type-3 secretion conference in #Japan.

I had to learn how to make an #origami pinwheel to do this - it took me ages. Then I realised the elaborate patterned paper I'd chosen was too wild, so I had to make the whole thing again!

A paper origami pinwheel is overlaid onto a circular protein ribbon assembly of a flagella filament, with painted bacteria swimming in the background. The pale pinks and warm cream colours evoke the idea of cherry blossom
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Kim

I'm getting better at staining. This is a sample from the bottom of the jar stained with aqueous methylene blue. I think maybe I can see two #flagella coming off one of the cells in the middle.

There's also one of the tube things in the middle there. It's interesting that the tubes don't stain. That would suggest they're not negatively charged the way most #bacteria are.

I'm thinking that what I've been calling tubes might be what other people call "safety pins". Apparently that's what Bukholderia are supposed to look like.

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