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@Co_Biologists<p>We are all set up at SDB.</p><p>Visit our table in the Miramar Ballroom to collect free giveaways from <span class="h-card" translate="no"><a href="https://biologists.social/@Dev_journal" class="u-url mention" rel="nofollow noopener" target="_blank">@<span>Dev_journal</span></a></span> and <span class="h-card" translate="no"><a href="https://biologists.social/@the_node" class="u-url mention" rel="nofollow noopener" target="_blank">@<span>the_node</span></a></span> and find out more about Open Access publishing, grants, events and our support for the developmental biology community.</p><p><a href="https://biologists.social/tags/SDB" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>SDB</span></a> <a href="https://biologists.social/tags/2025SDB" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>2025SDB</span></a> <a href="https://biologists.social/tags/2025ICDB" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>2025ICDB</span></a> <a href="https://biologists.social/tags/event" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>event</span></a> <a href="https://biologists.social/tags/community" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>community</span></a> <a href="https://biologists.social/tags/DevBio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>DevBio</span></a></p>
Sally Lowell<p>Developmental Biology, From Stem Cells to Morphogenesis: an advanced course for MSc and PhD students, run by the Sorbonne and the Curie in Paris.</p><p>Open to international students, free registration (not including room and board)</p><p><a href="https://training.institut-curie.org/courses/developmental-biology-2025" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">training.institut-curie.org/co</span><span class="invisible">urses/developmental-biology-2025</span></a></p><p><a href="https://biologists.social/tags/DevBio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>DevBio</span></a></p>
preLights<p>‘These cracks, they let the developing cells in: A chronicle of trabeculation in the developing zebrafish heart’ 🎵</p><p>Theodora Stougiannou highlights recent work from Christopher Chan Jin Jie, Rashmi Priya &amp; team. <a href="https://biologists.social/tags/preprint" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>preprint</span></a></p><p>Check out the <a href="https://biologists.social/tags/preLight" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>preLight</span></a> ⬇️ 👀<br><a href="https://prelights.biologists.com/highlights/mechanical-fracturing-of-the-extracellular-matrix-patterns-the-vertebrate-heart/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">prelights.biologists.com/highl</span><span class="invisible">ights/mechanical-fracturing-of-the-extracellular-matrix-patterns-the-vertebrate-heart/</span></a></p><p><a href="https://biologists.social/tags/DevBio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>DevBio</span></a> <a href="https://biologists.social/tags/biology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>biology</span></a> <a href="https://biologists.social/tags/heart" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>heart</span></a></p>
eLife<p>Authors of this <a href="https://fediscience.org/tags/DevBio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>DevBio</span></a> study, ranked fundamental, have included an ‘Ideas and Speculation’ section 💡</p><p>They propose possible mechanistic explanations of their research on BMP4 mutations that contribute to vertebrate development.<br><a href="https://elifesciences.org/reviewed-preprints/105018?utm_source=mastodon&amp;utm_medium=social&amp;utm_campaign=organic_assessment#s3a" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">elifesciences.org/reviewed-pre</span><span class="invisible">prints/105018?utm_source=mastodon&amp;utm_medium=social&amp;utm_campaign=organic_assessment#s3a</span></a></p>
Sally Lowell<p>There have been SO MANY preprints about gastruloids in recent months. It is great to see three of them summarised and placed into context here by Maroudas-Sacks et al. </p><p>I'm a big fan of InPreprints. If anyone of you want to write about your own favourite recent preprints do get in touch with <span class="h-card" translate="no"><a href="https://biologists.social/@Dev_journal" class="u-url mention" rel="nofollow noopener" target="_blank">@<span>Dev_journal</span></a></span> </p><p><a href="https://journals.biologists.com/dev/article/152/10/dev204870/367998/In-preprints-exploring-developmental-robustness" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">journals.biologists.com/dev/ar</span><span class="invisible">ticle/152/10/dev204870/367998/In-preprints-exploring-developmental-robustness</span></a></p><p><a href="https://biologists.social/tags/DevBio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>DevBio</span></a></p>
eLife<p>Organoids derived from placental tissue can be used to study processes involving syncytiotrophoblasts – cells that contain billions of nuclei – in the placenta. <a href="https://fediscience.org/tags/DevBio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>DevBio</span></a><br><a href="https://elifesciences.org/reviewed-preprints/101170?utm_source=mastodon&amp;utm_medium=social&amp;utm_campaign=organic" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">elifesciences.org/reviewed-pre</span><span class="invisible">prints/101170?utm_source=mastodon&amp;utm_medium=social&amp;utm_campaign=organic</span></a></p>
preLights<p>How do progenitor cells in the brain give rise to such a diverse range of cell types? 🧠</p><p>In his first <a href="https://biologists.social/tags/preLight" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>preLight</span></a>, Jethro Lundie-Brown discusses work showing that ASCL1 and FOXO1 work together to create inhibitory neurons from bipotent progenitors.</p><p><a href="https://biologists.social/tags/preprint" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>preprint</span></a> from Jens Bager Christensen &amp; team <a href="https://biologists.social/tags/BayinLab" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>BayinLab</span></a>.</p><p>Learn more! ⬇️<br><a href="https://prelights.biologists.com/highlights/a-conserved-differentiation-program-facilitates-inhibitory-neuron-production-in-the-developing-mouse-and-human-cerebellum/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">prelights.biologists.com/highl</span><span class="invisible">ights/a-conserved-differentiation-program-facilitates-inhibitory-neuron-production-in-the-developing-mouse-and-human-cerebellum/</span></a></p><p><a href="https://biologists.social/tags/biology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>biology</span></a> <a href="https://biologists.social/tags/neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>neuroscience</span></a> <a href="https://biologists.social/tags/DevBio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>DevBio</span></a> <a href="https://biologists.social/tags/cerebellum" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cerebellum</span></a></p>
eLife<p>Cell Signalling: Not all dimers are equal</p><p>Disease-causing mutations in the signalling protein BMP4 impair its secretion, but only when it is made as a homodimer. <a href="https://fediscience.org/tags/DevBio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>DevBio</span></a><br><a href="https://elifesciences.org/articles/106980?utm_source=mastodon&amp;utm_medium=social&amp;utm_campaign=organic_insights" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">elifesciences.org/articles/106</span><span class="invisible">980?utm_source=mastodon&amp;utm_medium=social&amp;utm_campaign=organic_insights</span></a></p>
eLife<p>Unravelling a signalling pathway</p><p>A new study reveals the network of molecules recruited by the signalling protein FGF during lens development. <a href="https://fediscience.org/tags/DevBio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>DevBio</span></a><br><a href="https://elifesciences.org/digests/103615/unravelling-a-signaling-pathway?utm_source=mastodon&amp;utm_medium=social&amp;utm_campaign=organic" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">elifesciences.org/digests/1036</span><span class="invisible">15/unravelling-a-signaling-pathway?utm_source=mastodon&amp;utm_medium=social&amp;utm_campaign=organic</span></a></p>
eLife<p>This study spotlights Meis2 as a key player in whisker follicle formation and shows that nerves aren’t needed to get things started. Some mysteries remain about how Meis2 works, but the imaging is ‘solid’ and the insights are sharp. <a href="https://fediscience.org/tags/DevBio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>DevBio</span></a><br><a href="https://elifesciences.org/articles/100854?utm_source=mastodon&amp;utm_medium=social&amp;utm_campaign=organic" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">elifesciences.org/articles/100</span><span class="invisible">854?utm_source=mastodon&amp;utm_medium=social&amp;utm_campaign=organic</span></a></p>
Sally Lowell<p>Reminder: deadline to apply for the Stem Cell Summer School is 30th May. And it's May already! So you have to apply this month!</p><p>A limited number of bursaries are available.</p><p>p.s. this year, the summer school coincides with the Spetses Armata Festival, so there will be a big party on the island 🙂</p><p><a href="https://www.stemcellsummerschool.org/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="">stemcellsummerschool.org/</span><span class="invisible"></span></a><br><a href="https://biologists.social/tags/StemCells" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>StemCells</span></a> <a href="https://biologists.social/tags/DevBio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>DevBio</span></a> <a href="https://biologists.social/tags/RegenerativeMedicine" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>RegenerativeMedicine</span></a></p>
preLights<p>Choking under pressure? 🥵</p><p>3D confinement in hydrogel-based culture inhibits muscle stem cell activation and differentiation. <a href="https://biologists.social/tags/preprint" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>preprint</span></a> from Woojin Han &amp; team.</p><p>“…this preprint demonstrates the interconnectedness of different subfields of biology.”</p><p>Check out the <a href="https://biologists.social/tags/preLight" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>preLight</span></a> of Justin Gutkowski ⬇️ 👀</p><p><a href="https://prelights.biologists.com/highlights/3d-mechanical-confinement-directs-muscle-stem-cell-fate-and-function/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">prelights.biologists.com/highl</span><span class="invisible">ights/3d-mechanical-confinement-directs-muscle-stem-cell-fate-and-function/</span></a></p><p><a href="https://biologists.social/tags/biology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>biology</span></a> <a href="https://biologists.social/tags/bioengineering" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>bioengineering</span></a> <a href="https://biologists.social/tags/DevBio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>DevBio</span></a> <a href="https://biologists.social/tags/genetics" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>genetics</span></a></p>
Sally Lowell<p>Generative Biology: A workshop to explore how synthetic biology can help us understand how embryos build themselves</p><p>Organised by Jake Cornwall-Scoones, Dirk Benzinger &amp; me</p><p>Oct 20-21, Brighton </p><p>Speakers:<br>Philip Ball<br>David Brückner<br>Francesca Ceroni<br>Jamie Davies<br>Pulin Li<br>Mattias Malaguti<br>Yolanda Schaerli<br>Ricard Solé<br>Berna Sozen<br>Ben Steventon<br>Jared Toettcher<br>Vikas Trivedi<br>Berta Verd<br>Sara Wickström</p><p>Places available for short talks and posters<br> <br><a href="https://thenode.biologists.com/generative-biology-new-approaches-to-study-developmental-design-principles/uncategorized/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">thenode.biologists.com/generat</span><span class="invisible">ive-biology-new-approaches-to-study-developmental-design-principles/uncategorized/</span></a></p><p><a href="https://biologists.social/tags/DevBio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>DevBio</span></a> <a href="https://biologists.social/tags/SyntheticBiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>SyntheticBiology</span></a></p>
eLife<p>Flatworms, but make it high-res. 🧠🪱</p><p>This new protocol combines tissue expansion + light-sheet microscopy to reveal planarian neural and muscle anatomy in 3D, at single-cell resolution. <a href="https://fediscience.org/tags/Planaria" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Planaria</span></a> <a href="https://fediscience.org/tags/Microscopy" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Microscopy</span></a> <a href="https://fediscience.org/tags/DevBio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>DevBio</span></a><br><a href="https://elifesciences.org/articles/101103?utm_source=mastodon&amp;utm_medium=social&amp;utm_campaign=organic" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">elifesciences.org/articles/101</span><span class="invisible">103?utm_source=mastodon&amp;utm_medium=social&amp;utm_campaign=organic</span></a></p>
Xenbase<p>Hello fellow froggers! Just over a week until the deadline for the Nikon Small World microscopy competition. Submit your images and show off the power of Xenopus! <a href="https://enter.nikonsmallworld.com" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="">enter.nikonsmallworld.com</span><span class="invisible"></span></a> <a href="https://mastodon.social/tags/science" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>science</span></a> <a href="https://mastodon.social/tags/devbio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>devbio</span></a> <a href="https://mastodon.social/tags/nikon" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>nikon</span></a> <a href="https://mastodon.social/tags/microscopy" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>microscopy</span></a> <a href="https://mastodon.social/tags/xenopus" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>xenopus</span></a> <a href="https://mastodon.social/tags/frogs" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>frogs</span></a></p>
@Co_Biologists<p>As <span class="h-card" translate="no"><a href="https://biologists.social/@the_node" class="u-url mention" rel="nofollow noopener" target="_blank">@<span>the_node</span></a></span> celebrates their 15 year anniversary this year, we want to collect feedback from you, our community, to ensure the Node is still relevant and useful.</p><p>If you’ve ever visited the Node to read, write or interact with the developmental and stem cell biology community, please spare five minutes to take their survey:</p><p><a href="https://surveymonkey.com/r/7QHYQCW" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="">surveymonkey.com/r/7QHYQCW</span><span class="invisible"></span></a></p><p><a href="https://biologists.social/tags/Development" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Development</span></a> <a href="https://biologists.social/tags/CellBiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>CellBiology</span></a> <a href="https://biologists.social/tags/Cell" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cell</span></a> <a href="https://biologists.social/tags/Biology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Biology</span></a> <a href="https://biologists.social/tags/Community" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Community</span></a> <a href="https://biologists.social/tags/DevBio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>DevBio</span></a></p>
Sally Lowell<p>Came to pay my respects to Alan Turing. Very moving.</p><p>The apple he holds represents Newton, the tree of knowledge, and forbidden love. It is also a reminder of Turing's death.</p><p><a href="https://biologists.social/tags/DevBio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>DevBio</span></a></p>
preLights<p>The tooth, the whole tooth and nothing but the… frog? – the not-so bite-sized mystery of frog tooth re-evolution 🐸🦷</p><p>Check out this really fun post prepared by Ryan Harrison, covering recent work from the <a href="https://biologists.social/tags/FraserLab" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>FraserLab</span></a>. <a href="https://biologists.social/tags/preprint" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>preprint</span></a></p><p><a href="https://biologists.social/tags/preLight" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>preLight</span></a> ⬇️ 👀<br><a href="https://prelights.biologists.com/highlights/tooth-development-in-frogs-implications-for-the-re-evolution-of-lost-mandibular-teeth-and-the-origin-of-a-morphological-innovation/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">prelights.biologists.com/highl</span><span class="invisible">ights/tooth-development-in-frogs-implications-for-the-re-evolution-of-lost-mandibular-teeth-and-the-origin-of-a-morphological-innovation/</span></a></p><p><a href="https://biologists.social/tags/DevBio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>DevBio</span></a> <a href="https://biologists.social/tags/teeth" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>teeth</span></a> <a href="https://biologists.social/tags/frogs" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>frogs</span></a> <a href="https://biologists.social/tags/evolution" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>evolution</span></a></p>
preLights<p>Listen to your gut – lessons from the brain. 🧠</p><p>Dang M. Nguyen &amp; team (<a href="https://biologists.social/tags/BilboLab" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>BilboLab</span></a>) demonstrate how prenatal environmental stressors disrupt gut immune cells, impair synaptic pruning in the gut + contribute to neurodevelopmental issues. <a href="https://biologists.social/tags/preprint" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>preprint</span></a></p><p>Another great <a href="https://biologists.social/tags/preLight" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>preLight</span></a> by Jeny Jose ⬇️ 👀</p><p><a href="https://prelights.biologists.com/highlights/prenatal-exposure-to-environmental-stressors-alters-gut-macrophage-development-and-gastrointestinal-function-of-male-offspring/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">prelights.biologists.com/highl</span><span class="invisible">ights/prenatal-exposure-to-environmental-stressors-alters-gut-macrophage-development-and-gastrointestinal-function-of-male-offspring/</span></a></p><p><a href="https://biologists.social/tags/biology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>biology</span></a> <a href="https://biologists.social/tags/immunology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>immunology</span></a> <a href="https://biologists.social/tags/neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>neuroscience</span></a> <a href="https://biologists.social/tags/DevBio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>DevBio</span></a> <a href="https://biologists.social/tags/gut" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>gut</span></a> <a href="https://biologists.social/tags/brain" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>brain</span></a> <a href="https://biologists.social/tags/highlight" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>highlight</span></a></p>
preLights<p>Heads or… Heads? 🤔</p><p>The Layden &amp; Rentzsch labs identify a possible role for the nervous system as a source of positional information during regeneration in the cnidarian Nematostella vectensis. <a href="https://biologists.social/tags/preprint" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>preprint</span></a></p><p>Another great <a href="https://biologists.social/tags/preLight" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>preLight</span></a> from Isabella Cisneros ⬇️ 👀</p><p><a href="https://prelights.biologists.com/highlights/ectopic-head-regeneration-after-nervous-system-ablation-in-a-sea-anemone/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">prelights.biologists.com/highl</span><span class="invisible">ights/ectopic-head-regeneration-after-nervous-system-ablation-in-a-sea-anemone/</span></a></p><p><a href="https://biologists.social/tags/biology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>biology</span></a> <a href="https://biologists.social/tags/DevBio" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>DevBio</span></a> <a href="https://biologists.social/tags/development" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>development</span></a> <a href="https://biologists.social/tags/genetics" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>genetics</span></a></p>