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#kidney

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Public
KimK ... one day at a time

"Using US healthcare data from over 280,000 adults, researchers found that #COVID19 doubled the 12-month risk of advanced chronic #kidney disease compared to influenza even in patients without early kidney injury."

nature.com/articles/s41598-025 ... via @atranscendedman #CKD #ESKD

NatureAssociation between COVID-19 and the development of chronic kidney disease in patients without initial acute kidney injury - Scientific ReportsWhile the association between COVID-19 and acute kidney injury (AKI) is well documented, the impact of COVID-19 on the development of advanced chronic kidney disease (CKD) remains unclear, particularly in patients without initial AKI. Using the TriNetX healthcare database, we conducted a matched cohort study comparing 141,587 COVID-19 and 141,587 influenza patients. We excluded patients with AKI within one month of infection and matched groups on demographics, comorbidities, and baseline laboratory values. The primary outcome was the incidence of advanced CKD (stages 3–5) at the 12-month follow-up. COVID-19 patients showed higher 12-month risks of advanced CKD (hazard ratio [HR]:2.02, 95% confidence interval [CI]:1.69–2.42, p < 0.0001), AKI (HR 3.04, 95%CI:2.61–3.55, p < 0.0001), and estimated glomerular filtration rate < 60 mL/min/1.73 m2 (HR:3.01, 95%CI:2.74–3.30, p < 0.0001) compared to influenza patients. Subgroup analyses showed consistently elevated risks across sexes and in patients over 45 years, while younger patients did not demonstrate an increased risk of advanced CKD at the 12-month follow-up. Diabetes mellitus and hypertension have emerged as the strongest predictors of advanced CKD development. In conclusion, COVID-19 is associated with an increased risk of long-term renal dysfunction compared with influenza, suggesting the need for extended monitoring of kidney function in high-risk populations.
Public
Bernhard Schermer

📣📣📣 Latest news from the NephroLab Cologne – more specifically, from our 🦛 Hippo- Team:
Our snRNA-Seq study on YAP and TAZ in kidney podocytes is now online open access in JASN! 🥳 🎉 🐙
Huge thanks to everyone on the team and the incredibly thorough reviewers at JASN!

Link: journals.lww.com/jasn/abstract

#HippoSignaling #YAP #TAZ #Kidney #Kidneydisease #Science #snRNASeq #cellsignaling #FSGS #podocyte #Nephrology #Niere #Nephrolab #Nephrologie

@ukkoeln @UniKoeln @CECAD

Detail of Figure 1: Schematic illustrating the strategy for isolating single nuclei from purified murine glomeruli, with podocyte-specific deletion of YAP or TAZ. UMAP plots show distinct clusters of podocytes.
Public
50+ Music

"Hands" is a song by American singer #Jewel, released as the first #single from her second studio album, #Spirit (1998). Jewel wrote the song following an incident in which she considered stealing a #sundress after getting fired from various jobs due to #kidney troubles, and she decided that her hands were better suited to writing songs than stealing clothes. Written as one of the last songs for the album.
youtube.com/watch?v=WGiVVC8hF80

YouTubeJewel - Hands (Official Lyric Video)By Jewel
Public *
KimK ... one day at a time

What's scary is the following re 90% ... 👇

"Around 90% of people with #kidney disease—9 in 10 adults—don’t know they have it. Why? Kidney disease often has no symptoms until its later stages. Many people are also unaware of their risk factors and don’t know when to get tested."

‼️ 90% ‼️

Take a moment to let that sink in.

I was not told that I have #CKD until I was diagnosed with #ESKD three years later in the ER.

kidney.org/news-stories/managi

What's scary is the following re 90% ... 👇 "Around 90% of people with #kidney disease—9 in 10 adults—don’t know they have it. Why? Kidney disease often has no symptoms until its later stages. Many people are also unaware of their risk factors and don’t know when to get tested." ‼️ 90% ‼️ Take a moment to let that sink in. I was not told that I have #CKD until I was diagnosed with #ESKD three years later in the ER. https://www.kidney.org/news-stories/managing-kidney-disease-every-stage-questions-to-ask-your-doctor #longCovid #chronic #illness ##WorldKidneyDay
#longCovid#chronic#illness
Public
50+ Music

"Hands" is a song by American singer #Jewel, released as the first #single from her second studio album, #Spirit (1998). Jewel wrote the song following an incident in which she considered stealing a #sundress after getting fired from various jobs due to #kidney troubles, and she decided that her hands were better suited to writing songs than stealing clothes. Written as one of the last songs for the album.
youtube.com/watch?v=WGiVVC8hF80

YouTubeJewel - Hands (Official Lyric Video)By Jewel
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