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Congratulations to Thomas Beneteau for his in-depth analysis of the #incidence and #duration of #HPV infections in young women using multivariate #Cox regression models with #frailty effects.

This work based on the #PAPCLEAR #cohort in #Montpellier and the #EVOLPROOF project is now published in #InfectiousDiseases.

#DM for a #PDF version until we can opt for #GreenOpenAccess.

doi.org/10.1080/23744235.2024.

New Research Sheds Light on Side Effects of COVID-19 Vaccination
Shortly following their COVID-19 vaccinations, individuals in Denmark reported mild side effects like general discomfort, elevated body temperature, and tiredness. Severe adverse reactions like facial paralysis and allergic responses are rare. Additionally, 30% of menstruating women reported alterations in their menstrual cycles.
scitechdaily.com/new-research- #Research #SideEffects #COVIDー19 #Vaccination #Danish #BiCoVac #cohort

SciTechDailyNew Research Sheds Light on Side Effects of COVID-19 VaccinationShortly following their COVID-19 vaccinations, individuals in Denmark reported mild side effects like general discomfort, elevated body temperature, and tiredness. Severe adverse reactions like facial paralysis and allergic responses are rare. Additionally, 30% of menstruating women reported alterat
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“This study of 340 489 service members found that the risk of disease was 70% higher in Camp Lejeune veterans compared with veterans stationed at a Marine Corps base where water was not contaminated. In veterans without Parkinson disease, risk was also significantly higher for several prodromal features of Parkinson disease.”

jamanetwork.com/journals/jaman

jamanetwork.comRisk of Parkinson Disease Among Camp Lejeune VeteransThis cohort study assesses the association between the contaminated water supply at Camp Lejeune and incidence of Parkinson disease among veterans who resided there between 1975 and 1985.
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A bit of history of studies, what it takes to maintain such large research resources, and my take on how to improve the situation were published today in the European Journal of Epidemiology @SpringerNature@twitter.com.

👉 link.springer.com/article/10.1

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SpringerLinkTowards a European “Cohort Moonshot”: revisiting the long-term strategy to support health research of tomorrow - European Journal of Epidemiology
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@fitterhappierAJ

RT @casanova_lab

4/ We previously proposed that #MIS-C is a type of #Kawasaki #Disease #triggered by a single #virus and might be caused by monogenic inborn errors of #immunity that can be detected by searching for #genetic homogeneity in a sufficiently large #cohort of #patients (doi.org/10.1084/jem.20…)

rupress.org/jem/article/218/6/

#sarscov2
@whn

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Élise has built a large breast cancer patient #cohort of about 230 000 patients (FRESH) mdpi.com/2072-6694/14/11/2671; proposed a new #deepLearning algorithm (EDEN) to label patient records according to whether there was a relapse or not arxiv.org/abs/2211.08077; and used #causalInference to identify medications unrelated to cancer that have an impact on cancer outcomes.

You can explore her results here (yes, she's also responsible for the cool graphics): adrenaline.curie.fr/

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MDPIThe French Early Breast Cancer Cohort (FRESH): A Resource for Breast Cancer Research and Evaluations of Oncology Practices Based on the French National Healthcare System Database (SNDS)Background: Breast cancer (BC) is the most frequent cancer and the leading cause of cancer-related death in women. The French National Cancer Institute has created a national cancer cohort to promote cancer research and improve our understanding of cancer using the National Health Data System (SNDS) and amalgamating all cancer sites. So far, no detailed separate data are available for early BC. Objectives: To describe the creation of the French Early Breast Cancer Cohort (FRESH). Methods: All French women aged 18 years or over, with early-stage BC newly diagnosed between 1 January 2011 and 31 December 2017, treated by surgery, and registered in the general health insurance coverage plan were included in the cohort. Patients with suspected locoregional or distant metastases at diagnosis were excluded. BC treatments (surgery, chemotherapy, targeted therapy, radiotherapy, and endocrine therapy), and diagnostic procedures (biopsy, cytology, and imaging) were extracted from hospital discharge reports, outpatient care notes, or pharmacy drug delivery data. The BC subtype was inferred from the treatments received. Results: We included 235,368 patients with early BC in the cohort (median age: 60 years). The BC subtype distribution was as follows: luminal (80.2%), triple-negative (TNBC, 9.5%); HER2+ (10.3%), or unidentifiable (n = 44,388, 18.9% of the cohort). Most patients underwent radiotherapy (n = 200,685, 85.3%) and endocrine therapy (n = 165,655, 70.4%), and 38.3% (n = 90,252) received chemotherapy. Treatments and care pathways are described. Conclusions: The FRESH Cohort is an unprecedented population-based resource facilitating future large-scale real-life studies aiming to improve care pathways and quality of care for BC patients.