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#testosterone

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Someone wrote a humorous toot about how there should be like a driver's license for #testosterone and I can't get that idea out of my head.
Looking at how humans behave, testosterone is probably the most destructive substance available to mankind? Alcohol (which is regulated) makes us destructive, but it can't even compare to testosterone.
I'm like, #men who are found guilty of #assault etc a couple of times: Mandatory 🍒✂️

Super Enzyme Regulates Testosterone Levels In Male Ruffs

"A single gene in the shorebird species known as ruffs controls the blood concentrations of testosterone in males, and this in turn affects their appearances and behavior"

#SciComm by @GrrlScientist

#testosterone #Androgens #hormones #MolecularBiology #Enzymes #shorebirds #birds #ornithology #GeneExpression #aggression medium.com/grrlscientist/super

Super Enzyme Regulates Testosterone Levels In Male Ruffs

"A single gene in the shorebird species known as ruffs controls the blood concentrations of testosterone in males, and this in turn affects their appearances and behavior"

#SciComm by @grrlscientist

#testosterone #Androgens #hormones #MolecularBiology #Enzymes #shorebirds #birds #ornithology #GeneExpression #aggression medium.com/grrlscientist/super

Super Enzyme Regulates Testosterone Levels In Male Ruffs

"A single gene in the shorebird species known as ruffs controls the blood concentrations of testosterone in males, and this in turn affects their appearances and behavior"

#SciComm by @grrlscientist

#testosterone #Androgens #hormones #MolecularBiology #Enzymes #shorebirds #birds #ornithology #GeneExpression #aggression medium.com/grrlscientist/super

I went from alto with hint of soprano in the mix if I really tried to apparently being able to sing "Hoist the colors" from Pirates of the Caribbean so that is how my testosterone taking is going.

I cannot, however, sing high parts at all because my voice breaks down. :P It feels weird to go from "Oh I just know how to sing ever since I was kid to - how the fuck do voice actually work??".

#T#singing#voice

Just had my annual visit to my endocrinologist. It's not good. Due to my testosterone my blood is too thick still which can lead to clots. Everything else to do with my levels are perfect. He suggested drinking more water might fix it until I told him that I drink 3L a day already. Then he asked if I'm eligible to donate blood every three months, I am not since I'm in a male male relationship. So the third option is to apply testogel to my shoulders every day. This is problematic for me because I am hopeless with introducing new routines to my carefully balanced schedule. Le sigh. I'm a bit devastated. I could go to a clinic that will take blood for $200, but I cannot afford that. So testogel it is. 😭

Influencia de la dieta paterna en los niveles de testosterona de la descendencia y sus consecuencias a través de alteraciones epigenéticas. Modelo de ratón.
nature.com/articles/s44324-024
#bianorbiotech #Mouse #diet #PaternalDiet #testosterone #aromatase #epigenetics

NaturePre-conceptional paternal diet impacts on offspring testosterone homoeostasis via epigenetic modulation of cyp19a1/aromatase activity - npj Metabolic Health and DiseasePaternal eating habits, before and at conception, have a strong impact on offspring future metabolism. By sending specific epigenetic signals through spermatozoa, paternal nutrition influences developing embryos and increases offspring risk of developing dysmetabolism and cardiovascular diseases. Among the intergenerational consequences, paternal epigenetic messages affect embryo DNA methylation altering programmed gene expression. The identification of offspring genetic loci that are epigenetically altered by paternal stimuli is of pivotal interest for timely post-natal treatment of offspring metabolic defects. We here use a murine model to show that, cyp19a1/aromatase, a gene coding for the cytochrome converting testosterone into 17-β estradiol (both potent hormonal mediators of embryo development and metabolism), is an epigenetic transducer of paternal intergenerational inheritance. By affecting cyp19a1 methylation status and alternative splicing, paternal diet coordinates androgens’ metabolism in the progeny affecting it in a sexually dimorphic way and promoting hypoandrogenism, growth retardation and diabetes in male pups.

Mecs trans, gens non-binaires, etc. de France, j'ai une question à vous poser :

A quelle fréquence et de dosage prenez-vous votre testostérone?

Mon endocrinologue (très sympa, très supportif) m'a commencé avec 0,5 ml de testostérone chaque deux semaines. Cependant, car mes niveaux de T étaient un peu élevés, il me bouger a 0,5ml chaque trois semaines.

Je continue d'avoir des effets de masculinisation, mais les derniers jours avant ma piqûre je trouve mes émotions très instables, ainsi que l'insomnie et l'anxiété. Je le trouve difficile.

La guide de FransGenre au sujet (partagenre.fransgenre.fr/resso) dit que :

«L’utilisation d'énanthèmes de T. avec des intervalles importants (toutes les 3 à 4 semaines) est inadaptée à la pharmacocinétique du produit et généralement à éviter.»

partagenre.fransgenre.frLes transitions masculinisantes - partagenre
Replied in thread

@jmcrookston

"Finally, study 4 found that higher #testosterone men showed stronger reactions to #masculinity threats than those lower in testosterone. Together, these results support the masculine overcompensation thesis, show how it can shape political and cultural attitudes, and identify a hormonal factor influencing the effect."

Or as in the saying: It's the *hormones*, stupid. 🙃
(while this is not the only shaping factor nor an excuse, of course)

Study PDF:
pacscenter.stanford.edu/wp-con
#toxic

Continued thread

I am not trying to scare anyone, I just want you to prepare to stock your fridge with healthy, easy access snacks, TONS of protein, and filling foods!

I failed to do this before my first injection yesterday, even though each gel increase made me feel like I had never seen food in my life (for like 1-2 months).

Now I am so hungry all sense has left my brain.

This is one of the reasons the side effects say "may cause weight gain" - other is muscle growth!