Ancient viral DNA found to regulate human gene expression
A new international study suggests that ancient viral DNA embedded in our genome, which were long dismissed as…
#NewsBeep #News #Genetics #AU #Australia #dna #Evolution #Gene #GeneExpression #Genes #Genetic #Genome #research #Science #StemCells #Transcription #TranscriptionFactors
https://www.newsbeep.com/au/4960/
https://www.europesays.com/uk/240940/ The role of untranslated region variants in Mendelian disease: a review #Bioinformatics #Biomedicine #Cytogenetics #DiseaseGenetics #GeneExpression #GeneRegulation #general #Genetics #HumanGenetics #Science #UK #UnitedKingdom
https://www.europesays.com/us/21397/ Discovery of a genetic dimmer switch controlling embryonic development #Cell #Chromatin #dna #Embryo #Gene #GeneExpression #genes #genetic #Genetics #Genome #genomics #laboratory #MedicalResearch #research #Science #UnitedStates #UnitedStates #US
https://www.europesays.com/uk/32997/ Report of a missense TJP2 variant associated to PFIC4 with a pronounced phenotypic variability: Focus on the structural effects on the protein level #ComputationalBiologyAndBioinformatics #GeneExpression #GeneFunction #GeneTherapy #Genetics #HumanGenetics #MolecularMedicine #NextGenerationSequencing #Paediatrics #Science #UK #UnitedKingdom
Whole-transcriptome profiling in C. briggsae and C. elegans reveals a post-reproductive shift in gene expression, indicating a dynamic regulation of aging-associated pathways linked to reproduction.
Link: doi.org/10.1093/gbe/...
The programme for the #bc2basel tutorials & workshops is out! From #geneexpression analysis to #machinelearning or #datavisualization, beginner or advanced: boost your #bioinformatics skills!
Register to make sure to secure your spot (limited seats): https://tinyurl.com/3y8ay2d6
Nicotina y fertilidad masculina: la exposición a este alcaloide altera la expresión génica durante la espermatogénesis, incluyendo las proteínas nucleares, afectando a la cromatina espermática. Revisión:
https://wjmh.org/DOIx.php?id=10.5534/wjmh.240072
#bianorbiotech #nicotine #SpermChromatin #MaleFertility #GeneExpression #review
The genome awakens: transposon-mediated gene regulation.
#Transposons #MITEs #GeneExpression #Review
https://www.cell.com/trends/plant-science/fulltext/S1360-1385(25)00039-1
Are you ready for #EMBLEpitrans? Prepare to deep dive into advances in RNA modification functions, their key roles in gene expression, disease, and transformative therapies. Be part of the community
Submit your abstract by 5 August
28 – 30 October
EMBL Heidelberg and Virtual
https://s.embl.org/etc25-01-ma
3/8 
For the first time (or do update us), we've modelled dynamic, plant gene circuits with absolute units for both RNA and protein copies per cell.
You can compare our mathematical models directly to your biochemical data. Over time, both approaches should benefit! #SystemsBiology
4/8 
Those absolute units mean that we can predict the DNA-binding dissociation constants (Kd) of our clock transcription factors in vivo, for example.
After some tricky calibration, we estimated comparable Kd values in vitro from our earlier data and the literature, extending the method to any promoter sequence (more on this later).
So, did they match?
Don’t miss the deadline 
27 February to submit your abstract to the [BC]2 Basel #ComputationalBiology Conference.
From #GeneExpression to #evolution or #biomedicine - we are waiting to learn more on your research projects at #bc2basel!
Scientific committee core team: Katja Bärenfaller, David Gfeller, Catherine Jutzeler, Abdullah Kahraman, and Diana Marek
Submit your abstract now: https://tinyurl.com/49w6wthj
Kreitman lab circa 2006
Susan Lott Sarah Wang Marty Kreitman Misha Ludwig
Great time to study developmental variation
Susans work culminated in
Canalization of segmentation and its evolution in Drosophila
#drosophila #geneExpression #evolution #development #EvenSkipped #eve #melanogaster #UChicago #biology
https://pmc.ncbi.nlm.nih.gov/articles/PMC1891814/
Explore the fascinating field of epigenetics and understand how your diet, exercise, and stress levels can impact your gene expression.
https://mrmedpharmacy.substack.com/p/the-epigenetics-of-health-preventing
#Cancer often resists treatment due to its complexity.
Kinga Kamieniarz-Gdula's new project targeting RNA 3’ processing is unlocking ways to study cancer #GeneExpression, & accelerate drug discovery.
#FrontierResearch #ERCPoC @EUinPL @POLAND25EU
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https://nitter.privacydev.net/ERC_Research/status/1882390335147667702#m
Oregon Health & Science University: OHSU part of national initiative to track gene expression beginning in early development. “Oregon Health & Science University has a leading role in a new database designed to track the normal expression of genes in organs and tissues from prenatal development through adulthood.”
Four years after publishing my work on machine-driven parameter screen of biochemical reactions, it still has zero citations. That makes me sad; I am really proud of this work. So I asked ChatGPT to suggest me hashtags, for another chance to reach readers. https://academic.oup.com/nar/article/48/7/e37/5728495 #MolecularBiology #BiochemicalReactions #ReverseTranscription #RNASequencing #LabAutomation #GeneExpression #SingleCellAnalysis #HighThroughput #AIinScience #ComputationalBiology #BiotechInnovation #DataDrivenResearch
“we introduce a concept called the gene dosage response curve (GDRC) that relates changes in gene expression to expected changes in phenotype. We show that, for many traits, GDRCs are systematically biased in one trait direction relative to the other and, surprisingly, that as many as 40% of GDRCs are non-monotone, with large increases and decreases in expression affecting the trait in the same direction. “
Now available ahead of print! "Effects of Testosterone on Gene Expression Are Concordant between Sexes but Divergent across Species of Sceloporus Lizards" by Robinson et al. https://www.journals.uchicago.edu/doi/10.1086/732200
Do you know gget by the Pachter lab? You should! It now includes efficient querying of Bgee in Python. Get high quality curated gene expression data directly in Python or command line. https://pachterlab.github.io/gget/en/bgee.html #RNAseq #biocuration #Python #scRNAseq @SIB @marcrr @fbastian @dee_unil
Integrating neuroimaging & molecular #brain data. @capra_lab @mika_rubinov &co present a resource that estimates genetically regulated components of #GeneExpression and infers associations of these with #neuroimaging & clinical phenotypes #PLOSBiology https://plos.io/3BidIcL
