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Auscandoc

“By analyzing a longitudinal cohort of individuals infected with during the first wave of infections, Cai et al. found that subsequent against enhanced the frequency and functional qualities of -specific . Despite up-regulation of inhibitory receptors, spike-specific T cells produced more effector and cytotoxic molecules after mstdn.social/@erictopol/111546

Mastodon 🐘Eric Topol (@erictopol@mstdn.social)Vaccination after Covid does not lead to T cell exhaustion—it invigorates T cell functionality https://www.science.org/doi/10.1126/sciimmunol.adh0687

@auscandoc

Doesn't matter much. MHC-I is functionally kaput. It doesn't matter how diligently an archer trains, they'll never win a contest without targets.

pnas.org/doi/10.1073/pnas.2221