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#intensivecare

1 post1 participant0 posts today
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Auscandoc

Of those, five were in , and nine people died with it.

So far this year, 175 people have died from or with Covid in WA, according to the Health Department, which means flu deaths are about two per cent of Covid deaths this year.

But schools don’t send out letters about Covid infections. They don’t warn people to be wary or tell parents to keep their children home from school.” (2/3)

Norobiik @Norobiik@noc.social

36 hour shifts, >100 work hours a week is a killing pace.
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The #doctors on walkout represent just a fraction of #SouthKorea’s 100,000 doctors, but they can make up more than 40% of staff at large teaching hospitals, performing crucial tasks in #EmergencyRooms, #IntensiveCare units and #OperatingRooms.

Overworked and unheard, South Korean doctors on mass #walkout
newsinfo.inquirer.net/1910567/

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Tilo Winkler

I'm happy to see our new editorial is out:
𝙒𝙞𝙣𝙠𝙡𝙚𝙧 𝙏 𝙖𝙣𝙙 𝘼𝙢𝙖𝙩𝙤 𝙈𝘽𝙋. 𝘼𝙡𝙫𝙚𝙤𝙡𝙖𝙧 𝙏𝙞𝙥𝙥𝙞𝙣𝙜 𝙋𝙤𝙞𝙣𝙩𝙨 𝙞𝙣 𝘾𝙝𝙖𝙣𝙜𝙞𝙣𝙜 𝙇𝙪𝙣𝙜𝙨 𝙍𝙚𝙡𝙖𝙩𝙚𝙙 𝙩𝙤 𝙋𝙤𝙨𝙞𝙩𝙞𝙫𝙚 𝙀𝙣𝙙-𝙚𝙭𝙥𝙞𝙧𝙖𝙩𝙤𝙧𝙮 𝙋𝙧𝙚𝙨𝙨𝙪𝙧𝙚.
doi.org/10.1097/ALN.0000000000

#respiratory#lung#physiology
Joanna Poole

Neat review on state of play in enrichment driven strategies for #sepsis #MedMastodon #icm #ccm #intensivecare #criticalcare #medicine

ccforum.biomedcentral.com/arti

BioMed CentralTargeting the host response in sepsis: current approaches and future evidence - Critical CareSepsis, a dysregulated host response to infection characterized by organ failure, is one of the leading causes of death worldwide. Disbalances of the immune response play an important role in its pathophysiology. Patients may develop simultaneously or concomitantly states of systemic or local hyperinflammation and immunosuppression. Although a variety of effective immunomodulatory treatments are generally available, attempts to inhibit or stimulate the immune system in sepsis have failed so far to improve patients’ outcome. The underlying reason is likely multifaceted including failure to identify responders to a specific immune intervention and the complex pathophysiology of organ dysfunction that is not exclusively caused by immunopathology but also includes dysfunction of the coagulation system, parenchymal organs, and the endothelium. Increasing evidence suggests that stratification of the heterogeneous population of septic patients with consideration of their host response might led to treatments that are more effective. The purpose of this review is to provide an overview of current studies aimed at optimizing the many facets of host response and to discuss future perspectives for precision medicine approaches in sepsis.
Joanna Poole

Interesting cluster analysis on sepsis - reinforces the idea that starting severity and geographical location influences the data so can’t always apply scores etc globally, but that “shock” and “sirs” are two phenotypes that can co exist and are reproducible - would these skew trials of vasopressor/toxin CRRT? t.ly/vN4rh #icm #criticalcare #icu #sepsis #intensivecare

link.springer.comExploring disease axes as an alternative to distinct clusters for characterizing sepsis heterogeneity
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