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Psychedelic Institute<a href="https://pubmed.ncbi.nlm.nih.gov/40313650/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1Jks6COFDAP2wn10NWIf-H0HaQXEJkWUqtjQ12xwhgtqZed1QU&fc=20250204204106&ff=20250502062629&v=2.18.0.post9+e462414" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://pubmed.ncbi.nlm.nih.gov/40313650/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1Jks6COFDAP2wn10NWIf-H0HaQXEJkWUqtjQ12xwhgtqZed1QU&fc=20250204204106&ff=20250502062629&v=2.18.0.post9+e462414</a> Intravenous Ketamine Treatment for Depression: One-year Retrospective Study from a Tertiary Care Psychiatry Center from India (Yadev, et al, 2025) <a href="https://mastodon.social/tags/ketamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamine</a> <a href="https://mastodon.social/tags/psychedelic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelic</a> <a href="https://mastodon.social/tags/ketaminetherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminetherapy</a> <a href="https://mastodon.social/tags/psychedelics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelics</a> <a href="https://mastodon.social/tags/psychedelicresesrch" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelicresesrch</a> <a href="https://mastodon.social/tags/mentalhealth" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#mentalhealth</a> <a href="https://mastodon.social/tags/ketaminesafety" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminesafety</a> <a href="https://mastodon.social/tags/depression" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#depression</a> <a href="https://mastodon.social/tags/neuroscience" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#neuroscience</a>

Psychedelic Institute<a href="https://pubmed.ncbi.nlm.nih.gov/40299391/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1Jks6COFDAP2wn10NWIf-H0HaQXEJkWUqtjQ12xwhgtqZed1QU&fc=20250204204106&ff=20250429124155&v=2.18.0.post9+e462414" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://pubmed.ncbi.nlm.nih.gov/40299391/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1Jks6COFDAP2wn10NWIf-H0HaQXEJkWUqtjQ12xwhgtqZed1QU&fc=20250204204106&ff=20250429124155&v=2.18.0.post9+e462414</a> Effects of Subanesthetic Intravenous Ketamine Infusion on Stress Hormones and Synaptic Density in Rats with Mild Closed-Head Injury (Boese, et al, 2025) <a href="https://mastodon.social/tags/tbi" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#tbi</a> <a href="https://mastodon.social/tags/brains" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#brains</a> <a href="https://mastodon.social/tags/stress" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#stress</a> <a href="https://mastodon.social/tags/neuroplasticity" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#neuroplasticity</a> <a href="https://mastodon.social/tags/ketamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamine</a> <a href="https://mastodon.social/tags/ketaminetherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminetherapy</a> <a href="https://mastodon.social/tags/psychedelics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelics</a> <a href="https://mastodon.social/tags/psychedelic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelic</a> <a href="https://mastodon.social/tags/ketaminesafety" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminesafety</a> <a href="https://mastodon.social/tags/psychedelicresearch" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelicresearch</a> <a href="https://mastodon.social/tags/mentalhealth" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#mentalhealth</a>

Psychedelic InstituteA Comparison of Ketamine to Midazolam for the Management of Acute Behavioral Disturbance in the Out-of-Hospital Setting - PubMed <a href="https://flip.it/EuhdzH" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://flip.it/EuhdzH</a> Una comparación de la ketamina con el midazolam para el manejo de los trastornos agudos del comportamiento en el entorno fuera del hospital <a href="https://mastodon.social/tags/ketamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamine</a> <a href="https://mastodon.social/tags/ketamina" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamina</a> <a href="https://mastodon.social/tags/psychedelic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelic</a> <a href="https://mastodon.social/tags/psychedelics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelics</a> <a href="https://mastodon.social/tags/emergencymedicine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#emergencymedicine</a> <a href="https://mastodon.social/tags/psychedelic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelic</a> <a href="https://mastodon.social/tags/psychiatry" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychiatry</a> <a href="https://mastodon.social/tags/neuroscience" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#neuroscience</a> <a href="https://mastodon.social/tags/mentalhealth" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#mentalhealth</a> <a href="https://mastodon.social/tags/nursing" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#nursing</a> <a href="https://mastodon.social/tags/behavioralhealth" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#behavioralhealth</a> <a href="https://mastodon.social/tags/spravato" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#spravato</a> <a href="https://mastodon.social/tags/psychedelicresearch" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelicresearch</a> <a href="https://mastodon.social/tags/research" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#research</a> <a href="https://mastodon.social/tags/ketaminesafety" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminesafety</a>

Psychedelic Institute<a href="https://link.springer.com/article/10.1007/s40263-025-01180-w" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://link.springer.com/article/10.1007/s40263-025-01180-w</a> Impact of Medical Comorbidities on Ketamine and Esketamine Treatment Effectiveness for Posttraumatic Stress Disorder and Depression: A Clinical Outcomes Analysis from the VA San Diego Healthcare System (Zhang, et al, 2025) <a href="https://mastodon.social/tags/ketamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamine</a> found effective for <a href="https://mastodon.social/tags/depression" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#depression</a> and <a href="https://mastodon.social/tags/ptsd" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ptsd</a> and safe to administer repeatedly even for those with traumatic brain injuries and obstructive sleep apnea <a href="https://mastodon.social/tags/mentalhealth" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#mentalhealth</a> <a href="https://mastodon.social/tags/ketaminetherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminetherapy</a> <a href="https://mastodon.social/tags/psychedelic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelic</a> <a href="https://mastodon.social/tags/psychedelics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelics</a> <a href="https://mastodon.social/tags/psychedelictherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelictherapy</a> <a href="https://mastodon.social/tags/ketaminesafety" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminesafety</a>

Psychedelic InstituteChronic, combinatorial targeting of NMDARs and 5-HT4Rs exerts extended behavioral effects against stress-induced perseverative behavior and hyponeophagia (Chen, et al, 2025) <a href="https://mastodon.social/tags/ketamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamine</a> <a href="https://mastodon.social/tags/ketaminetherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminetherapy</a> <a href="https://mastodon.social/tags/psychedelic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelic</a> <a href="https://mastodon.social/tags/psychedelics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelics</a> <a href="https://mastodon.social/tags/psychedelicresearch" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelicresearch</a> <a href="https://mastodon.social/tags/mentalhealth" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#mentalhealth</a> <a href="https://mastodon.social/tags/ketaminesafety" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminesafety</a> <a href="https://mastodon.social/tags/drugsafety" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#drugsafety</a> <a href="https://mastodon.social/tags/neuroscience" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#neuroscience</a>

Psychedelic InstituteToday you learned they give ketamine as part of anesthesia DURING OPEN HEART SURGERY <a href="https://mastodon.social/tags/ketamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamine</a> <a href="https://mastodon.social/tags/psychedelics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelics</a> <a href="https://mastodon.social/tags/ketaminesafety" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminesafety</a> <a href="https://mastodon.social/tags/drugsafety" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#drugsafety</a> Etomidate vs Ketamine-Propofol for Induction of Anesthesia in Coronary Artery Bypass Grafting: An Updated Systematic Review and Meta-Analysis (Kumar, et al 2025) <a href="https://pubmed.ncbi.nlm.nih.gov/40221834/" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://pubmed.ncbi.nlm.nih.gov/40221834/</a>

Psychedelic Institute<a href="https://www.sciencedirect.com/science/article/pii/S2666915325000344" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.sciencedirect.com/science/article/pii/S2666915325000344</a> Ketamine treatment for depression in elderly inpatients: an observational case series (Römer, et al, 2025) <a href="https://mastodon.social/tags/ketamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamine</a> <a href="https://mastodon.social/tags/ketaminetherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminetherapy</a> <a href="https://mastodon.social/tags/ketaminesafety" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminesafety</a> <a href="https://mastodon.social/tags/ketamineassistedtherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamineassistedtherapy</a> Note: in their very small sample, they note effects were short lived. The effects are still longer-lasting than standard antidepressants which require daily dosing. Side note - people who drink ayahausca culturally do so about once a month their entire lives. <a href="https://mastodon.social/tags/psychedelics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelics</a> <a href="https://mastodon.social/tags/perspective" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#perspective</a>

Psychedelic Institute<a href="https://psychedelicmentalhealth.net/spotlight-on-rare-but-relevant-ketamine-induced-cystitis-an-in-depth-review-for-addiction-medicine-and-psychedelic-harm-reduction-psychotherapy-support/" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://psychedelicmentalhealth.net/spotlight-on-rare-but-relevant-ketamine-induced-cystitis-an-in-depth-review-for-addiction-medicine-and-psychedelic-harm-reduction-psychotherapy-support/</a> Spotlight: On "Rare but relevant: Ketamine-induced cystitis - an in-depth review for addiction medicine" (Abdelrhamen, et Belal 2025) and psychedelic harm reduction psychotherapy, support <a href="https://mastodon.social/tags/ketamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamine</a> <a href="https://mastodon.social/tags/psychedelics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelics</a> <a href="https://mastodon.social/tags/poppers" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#poppers</a> <a href="https://mastodon.social/tags/paracetamol" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#paracetamol</a> <a href="https://mastodon.social/tags/plantmedicine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#plantmedicine</a> <a href="https://mastodon.social/tags/ayahausca" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ayahausca</a> <a href="https://mastodon.social/tags/antidepressants" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#antidepressants</a> <a href="https://mastodon.social/tags/karmreduction" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#karmreduction</a> <a href="https://mastodon.social/tags/psychedelictherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelictherapy</a> <a href="https://mastodon.social/tags/chinesewisdon" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#chinesewisdon</a> <a href="https://mastodon.social/tags/cognitivebehavioraltherapy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#cognitivebehavioraltherapy</a> <a href="https://mastodon.social/tags/ketaminesafety" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminesafety</a> <a href="https://mastodon.social/tags/recovery" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#recovery</a> <a href="https://mastodon.social/tags/substanceusedisorder" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#substanceusedisorder</a> <a href="https://mastodon.social/tags/lorazepam" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#lorazepam</a>

Psychedelic InstituteKetamine as part of multi-modal analgesia may reduce <a href="https://mastodon.social/tags/opioid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#opioid</a> requirements following cardiac surgery: a retrospective observational cohort study (Hall, et al, 2025) <a href="https://pubmed.ncbi.nlm.nih.gov/40181432/" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://pubmed.ncbi.nlm.nih.gov/40181432/</a> <a href="https://mastodon.social/tags/ketamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamine</a> <a href="https://mastodon.social/tags/ketaminesafety" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminesafety</a> <a href="https://mastodon.social/tags/cardiacicu" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#cardiacicu</a> <a href="https://mastodon.social/tags/painmanagement" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#painmanagement</a> <a href="https://mastodon.social/tags/cardiaccare" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#cardiaccare</a> Note - ketamine found safe to use post heart surgery for pain management with no cases of respiratory depression or mortalities. <a href="https://mastodon.social/tags/psychedelic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelic</a> <a href="https://mastodon.social/tags/psychedelics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelics</a> <a href="https://mastodon.social/tags/psychedelicresearch" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelicresearch</a> <a href="https://mastodon.social/tags/harmreduction" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#harmreduction</a> <a href="https://mastodon.social/tags/drugsafety" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#drugsafety</a>

Psychedelic InstituteThe Sedative and Haemodynamic effects Of Continuous Ketamine infusions on Intensive Care Unit patients (SHOCK-ICU): Investigating key outcomes, resource utilisation and staff decision-making: Clinical feasibility study protocol (Richards, et al, 2025) <a href="https://mastodon.social/tags/ketamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamine</a> <a href="https://mastodon.social/tags/icu" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#icu</a> <a href="https://mastodon.social/tags/ketaminesafety" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminesafety</a> <a href="https://mastodon.social/tags/psychedelicresearch" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelicresearch</a> <a href="https://mastodon.social/tags/psychedelics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelics</a> <a href="https://mastodon.social/tags/psychedelic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelic</a> <a href="https://mastodon.social/tags/intensivecare" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#intensivecare</a> <a href="https://pubmed.ncbi.nlm.nih.gov/40171294/" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://pubmed.ncbi.nlm.nih.gov/40171294/</a>

Psychedelic InstituteUse of ketamine for reversing acute depression in a critically ill pretransplant patient (Shapiro, et al, 2025) <a href="https://mastodon.social/tags/ketamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamine</a> <a href="https://mastodon.social/tags/psychedelic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelic</a> <a href="https://mastodon.social/tags/psychedelics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#psychedelics</a> <a href="https://mastodon.social/tags/depression" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#depression</a> <a href="https://mastodon.social/tags/deathanxiety" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#deathanxiety</a> Note: Ketamine safe enough to administer to a patient in ICU with ischemic cardiomyopathy. <a href="https://mastodon.social/tags/ketaminesafety" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminesafety</a>

Psychedelic Institute<a href="https://pubmed.ncbi.nlm.nih.gov/40129893/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1Jks6COFDAP2wn10NWIf-H0HaQXEJkWUqtjQ12xwhgtqZed1QU&fc=20250204204106&ff=20250325062530&v=2.18.0.post9+e462414" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://pubmed.ncbi.nlm.nih.gov/40129893/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1Jks6COFDAP2wn10NWIf-H0HaQXEJkWUqtjQ12xwhgtqZed1QU&fc=20250204204106&ff=20250325062530&v=2.18.0.post9+e462414</a> High-Frequency Analysis of the Cerebral Physiological Impact of Ketamine in Acute Traumatic Neural Injury (McClarty, et al, 2025) “findings suggest that <a href="https://mastodon.social/tags/ketamine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketamine</a> does not significantly impact cerebral pressure-flow dynamics, challenging historical concerns about its use in patients with TBI.” <a href="https://mastodon.social/tags/traumaticbraininjury" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#traumaticbraininjury</a> <a href="https://mastodon.social/tags/ketaminesafety" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ketaminesafety</a>

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