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sequelae in athletes following COVID-19 vaccination: evidence and misinformation | British Journal of Sports Medicine bjsm.bmj.com/content/57/21/140 “Currently, the available evidence does not support claims that leads to an elevated risk of myocardial sequelae or in athletes when compared to native infection.”

British Journal of Sports Medicine · Cardiac sequelae in athletes following COVID-19 vaccination: evidence and misinformationThe recognition of myocarditis as a rare side effect of SARS-CoV-2 mRNA vaccination by the US Food and Drug Administration and European Medicines Agency has led to global debate regarding vaccine safety, particularly within the world of sports. A plethora of speculative reports on social media attribute sudden cardiac arrest/death (SCA/D) in athletes to mRNA vaccination. We, therefore, aim to provide: (1) a comprehensive overview of current literature on SARS-CoV-2 vaccination safety in athletes; (2) a theoretical overview of potential COVID-19 mRNA vaccination-associated myocarditis (C-VAM) pathogeneses; (3) performance considerations and (4) a critical appraisal of circulating reports on vaccine-induced adverse cardiac events in athletes. A subgroup analysis in individuals under 40 years of age estimated an excess 2 and 8 cases of myocarditis per 1 million first doses, and an excess 3 and 15 cases per 1 million second doses of the BNT162b2 (BioNTech, Pfizer) and mRNA-1273 (Moderna) vaccine, respectively. This contrasts with 10 extra cases of myocarditis per 1 million positive SARS-CoV-2 tests (figure 1).1 However, no confirmed cases of athletes with cardiac complications following mRNA vaccination have been reported to date. A PubMed search (15 February 2023) using the terms ‘vaccine’, ‘(peri)myocarditis’, ‘SARS-CoV-2’ and ‘athlete’ (online supplemental appendix A) yielded nine results. None of these contained original data except one case report of a woman athlete who developed pericarditis after a Bentall procedure and mRNA COVID-19 vaccine administration. Although the interval between vaccination and the onset of her symptoms was peculiar, the a priori chance of …

“A subgroup analysis in individuals under 40 years of age estimated an excess 2 and 8 cases of myocarditis per 1 million first doses, and an excess 3 and 15 cases per 1 million second doses of the BNT162b2 (BioNTech, Pfizer) and mRNA-1273 (Moderna) vaccine, respectively. This contrasts with 10 extra cases of myocarditis per 1 million positive SARS-CoV-2 tests .1 However, no confirmed cases of athletes with cardiac complications following mRNA vaccination have been reported to date.”

Auscandoc

has made a public statement reporting no notable increase in based on the official FIFA registry. A recent Australian study investigating the prevalence of out-of-hospital cardiac arrest () following infection and vaccination in over 4million young individuals demonstrated no increase in OHCA rates or as a contributing factor to OHCA.”