Create accountLogin

Recent searches

No recent searches

Search options

Only available when logged in.
med-mastodon.com is one of the many independent Mastodon servers you can use to participate in the fediverse.
Medical community on Mastodon

Administered by:

Server stats:

411
active users

med-mastodon.com: AboutProfiles directoryPrivacy policy

Mastodon: AboutGet the appKeyboard shortcutsView source codev4.3.8

#MovementDisorders

0 posts0 participants0 posts today
Replied in thread
Public *
Paul Chambers🚧

@DoomsdaysCW Now, UI devs need to work on some of their elements that affect movement disorders.

A lot of websites are using features that if you click outside a popup, like for searching or filling out a form, the popup closes. A simple way to turn that off and provide an X or close button would do wonders. I love that Mastodon at least buffers that somewhat, esp if you are writing a post and accidently click which would lead you away from what you are working on

It's not just for people with the most widely known form of #MovementDisorders, like #Parkinsons, but all people as they age get tremors, dystonia, and ataxia, some just an annoyance, but others significant, as their damaged nervous system breaks down communication with their brains through the simple act of aging and lifestyle choices. #a11y .

@rolle

Public
SCAB Pharmacy Limited

𝗪𝗼𝗿𝗹𝗱 𝗠𝗼𝘃𝗲𝗺𝗲𝗻𝘁 𝗗𝗶𝘀𝗼𝗿𝗱𝗲𝗿𝘀 𝗗𝗮𝘆 - 𝗡𝗼𝘃𝗲𝗺𝗯𝗲𝗿 𝟮𝟵𝘁𝗵

Join us in raising awareness about movement disorders and their impact on lives. These neurological conditions can affect a person's ability to control movements and include symptoms like slowed and involuntary movements, tremors, stiffness, and even non-motor symptoms such as constipation and hallucinations.

On this day, we commemorate the birth of Prof. Jean-Martin Charcot, the "Father of French Neurology," whose contributions have paved the way for understanding these complex disorders.

𝗞𝗲𝘆 𝗙𝗮𝗰𝘁𝘀:
Movement disorders include Parkinson's disease, Restless legs, Chorea, Myoclonus, Dystonia, and Ataxia.
Non-motor symptoms significantly affect quality of life.
Treatment options may alleviate symptoms but require ongoing management.
Let’s support those affected and promote understanding! 💚

#WorldMovementDisordersDay#MovementDisorders#ParkinsonsDisease
Public
Dr. Marie McNeely

In the latest episode of The Parkinson's Research Podcast, I had a chance to sit down with Dr. Antonella Santuccione Chadha to talk about her work with the Women's Brain Project and the importance of considering sex and gender factors in Parkinson's disease research, policy, and healthcare.

Click here to listen:
michaeljfox.org/podcast/episod

The Michael J. Fox Foundation for Parkinson's Research | Parkinson's DiseaseEpisode 11: The Importance of Sex and Gender Factors in Neurodegenerative Disease Research and Care with Antonella Santuccione ChadhaOur guest Dr. Antonella Santuccione Chadha discusses her work with the Women’s Brain Project, their recent roundtable on enhancing care in Parkinson’s disease, and the organization's goals for the future.
#parkinsons#parkinsonsdisease#neuroscience
Public
Dr. Marie McNeely

Dr. Huw Morris has spent more than twenty five years researching Parkinson's disease and parkinsonian syndromes, and he shares highlights from recent work in this podcast episode, including studies on the genetics and pathogenesis of Parkinson’s disease and other parkinsonian syndromes.

michaeljfox.org/podcast/episod

This image shows the cover art for the podcast linked in the post. The text on the left reads "The Parkinson's Research Podcast: New Discoveries in Neuroscience". The logo for The Michael J. Fox Foundation For Parkinson's Research appears in the bottom left corner in orange. There is an abstract line drawing of a microscope in orange going across the middle and on the right side of the image.
#parkinsonsdisease#parkinsons#movementdisorders
Public
Dominic Boutet

#arxivfeed

"Distinct excitability of thalamocortical neurons correlates with the presence of cerebellar afferents"
biorxiv.org/content/10.1101/20

bioRxivDistinct excitability of thalamocortical neurons correlates with the presence of cerebellar afferentsThalamocortical (TC) neurons within the ventrolateral thalamus (VL) receive projections from the cerebellum and the basal ganglia (BG) to facilitate motor and non-motor functions. Tonic and rebound firing patterns in response to excitatory cerebellar and inhibitory BG inputs, respectively, are a canonical feature of TC neurons and plays a key role in signal processing. The intrinsic excitability of TC neurons has a strong influence on how they respond to synaptic inputs, however, it is unknown whether their afferents influence their firing properties. Understanding the input-specific firing patterns could shed light into movement disorders with cerebellar or BG involvement. Here, we used whole-cell electrophysiology in brain slices from C57BL/6 mice to investigate the firing of TC neurons with optogenetic confirmation of cerebellar or BG afferents. TC neurons with cerebellar afferents exhibited higher tonic and rebound firing rates than those with BG afferents. This increased firing was associated with faster action potential depolarization kinetics and a smaller afterhyperpolarization potential. We also found differences in the passive membrane properties and sag currents during hyperpolarization. Despite higher rebound firing in TC neurons with cerebellar afferents, there were no differences in T-type calcium channel function compared to those with BG inputs. These data suggest input-specific differences in sodium and SK, but not T-type calcium channels, impact firing properties in TC populations. Altogether, we showed that the pronounced divergence observed in TC neuron firing properties correlate with its heterogeneous anatomical connectivity, which could signify a distinct signal integration and processing by these neurons. ### Competing Interest Statement The authors have declared no competing interest.
#Neuroscience#Electrophysiology#Cerebellum
Public
dystobot

[Automatic repost twitter.com/dystobot/status/16]

RT @dr_rohit_gupta: Deep Brain Stimulation (DBS)? It's a medical treatment that uses small electrodes placed in the brain to help control movement disorders like Parkinson's disease, dystonia, and essential tremor

t.co/fwiA9to4U5

Twitterdystobot on Twitter“RT @dr_rohit_gupta: Deep Brain Stimulation (DBS)? It's a medical treatment that uses small electrodes placed in the brain to help control m…”
Public *
Alessandro D'Ausilio

#NewPaper #Neuroscience

Another cool #Anatomy paper on the connectivity between #BasalGanglia and the #Cerebellum

Here some quotes:

"Neural processing in the basal ganglia is critical for normal movement.
...
Many believe that the basal ganglia influence movement via thalamic projections to motor areas of the cerebral cortex and through projections to the cerebellum, which also projects to the motor cortex via the thalamus.
...
However, lesions that interrupt these thalamic pathways to the cortex have little effect on many movements, including limb movements.
...
In this report, we describe several brainstem pathways that connect basal ganglia output to the cerebellum via nucleus reticularis tegmenti pontis (NRTP).
...
The basal ganglia could ... alter movements via descending projections of the cerebellum.
...
Pathways through NRTP ... may underlie deficits associated with basal ganglia disease."

link.springer.com/article/10.1

SpringerLinkNucleus reticularis tegmenti pontis: a bridge between the basal ganglia and cerebellum for movement control - Experimental Brain ResearchNeural processing in the basal ganglia is critical for normal movement. Diseases of the basal ganglia, such as Parkinson’s disease, produce a variety of movement disorders including akinesia and bradykinesia. Many believe that the basal ganglia influence movement via thalamic projections to motor areas of the cerebral cortex and through projections to the cerebellum, which also projects to the motor cortex via the thalamus. However, lesions that interrupt these thalamic pathways to the cortex have little effect on many movements, including limb movements. Yet, limb movements are severely impaired by basal ganglia disease or damage to the cerebellum. We can explain this impairment as well as the mild effects of thalamic lesions if basal ganglia and cerebellar output reach brainstem motor regions without passing through the thalamus. In this report, we describe several brainstem pathways that connect basal ganglia output to the cerebellum via nucleus reticularis tegmenti pontis (NRTP). Additionally, we propose that widespread afferent and efferent connections of NRTP with the cerebellum could integrate processing across cerebellar regions. The basal ganglia could then alter movements via descending projections of the cerebellum. Pathways through NRTP are important for the control of normal movement and may underlie deficits associated with basal ganglia disease.
#Parkinson#MotorControl#MovementDisorders
ExploreLive feeds
About