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Mechanism of #methyltransferase METTL8-mediated #mitochondrial #RNA m3C modification and its relaxed substrate specificity.
https://phys.org/news/2023-09-mechanism-methyltransferase-mettl8-mediated-mitochondrial-rna.html
Phys.org · Mechanism of methyltransferase METTL8-mediated mitochondrial RNA m3C modification and its relaxed substrate specificity
Cells with stochastically increased #methyltransferase to #restriction #endonuclease ratio provide an entry for #bacteriophage into protected cell population -
PubMedCells with stochastically increased methyltransferase to restriction endonuclease ratio provide an entry for bacteriophage into protected cell population - PubMedThe action of Type II restriction-modification (RM) systems depends on restriction endonuclease (REase), which cleaves foreign DNA at specific sites, and methyltransferase (MTase), which protects host genome from restriction by methylating the same sites. We here show that protection from phage infe …