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#anaphylaxis

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Analysis of over 1,100 Canadians who sought medical help for anaphylactic shock found that alcohol consumption was associated with the severity of reaction to nut allergies (peanut or tree-not; not specified).

Summary: mcgill.ca/newsroom/channels/ne

Original paper: karger.com/iaa/article/doi/10.

NewsroomStudy links alcohol consumption to more severe nut allergy reactionFindings of a new study into severe allergic reactions offer a sobering warning to people allergic to tree nuts and, more broadly, could lead to quicker diagnoses in emergency care for people with all anaphylactic allergies. The McGill University-led study by Dr. Moshe Ben-Shoshan’s team found that drinking alcohol was linked to more severe reactions in nut allergies. They also raise the possibility that nut-flavoured alcoholic drinks, even those made with artificial flavouring, could still expose people to trace allergens and increase the risk of severe reaction. More broadly, the study found patterns between the triggers and symptoms of anaphylaxis, an allergic reaction that can be fatal within minutes if untreated. Food was found to be the most common trigger, responsible for over half of cases. Among these, tree nuts stood out for their strong link to throat tightness compared to other allergens. Reactions from the venom of insect stings were more likely to trigger heart-related problems like a decrease in blood pressure. Bridging data gaps in adult anaphylaxis Anaphylaxis is most often caused by food, bug bites or medications. While doctors often treat it effectively with epinephrine, the authors say they rarely understand why certain triggers cause specific symptoms, a knowledge gap that can delay diagnosis and treatment. “For doctors, spotting patterns could mean faster, life-saving treatment in emergencies. For people with allergies, understanding the role of alcohol and other triggers can help them make safer choices,” said lead author Roy Khalaf, a fourth-year medical student in McGill’s Faculty of Medicine and Health Sciences. "With the holiday season’s abundance of nut-based treats and specialty beverages, the risk of accidental exposure to allergens requires careful attention,” he said. The findings may also have implications for labelling practices in the food and beverage industry, he added, emphasizing the importance of clear allergen information to protect consumers. The study, published in International Archives of Allergy and Immunology, is one of the first large-scale Canadian efforts to investigate anaphylaxis in adults, an area the researchers say lacks data. They analyzed data from over 1,100 cases treated in Canadian emergency rooms over 10 years. Next, the team aims to explore milder reactions outside of emergency care and investigate the connection between nuts and alcohol to improve allergy management. The study was a collaborative effort orchestrated by Dr. Ben-Shoshan, Assistant Professor, Division of Allergy and Immunology and Clinical Dermatology, Montreal Children's Hospital, McGill University Health Centre (MUHC). It included researchers from the University of Calgary, the University of British Columbia, Memorial University, McMaster University, the University of Toronto, and the University of Manitoba. About the study “Symptomatology and Management of Adult Anaphylaxis according to Trigger: A Cross-Sectional Study” by Roy Khalaf et al., was published in International Archives of Allergy and Immunology. It was conducted without external sponsorship or funding.
#Science#Health#Nut

When I was first diagnosed with MCAS I thought “a condition I can control!”

I genuinely believed that since there were clear & obvious triggers - I could put in the work, overhaul my life and be free of attacks.

When a patient plans - mast cells laugh.

I threw myself into research trying to learn how to adopt a low histamine diet, clean my air and change my body care and cleaning products.

I (falsely) assumed that if I made enough changes - sacrificed HARD enough - I wouldn’t have to deal with flare ups.

It was exhausting. Many of the changes DID help. A low histamine diet, cleaner air, a proper med and supplement schedule and non toxic cleaning products all helped to reduce my overall “bucket” so that my symptoms were less severe.

The problem was - I continued having attacks. From minor attacks to full blown anaphylaxis - no matter how much work I put in the attacks didn’t stop.

It was incredibly frustrating - and I began tracking everything I ate, used or did in an effort to find patterns.

In the end I realized that sometimes - there are no answers. “Putting in the work” doesn’t guarantee you won’t have attacks.

It’s a help - and we should do whatever we can to minimize our symptoms - but chronic illness (and especially MCAS) doesn’t care about your plans.

I had to learn to let go. Constantly blaming myself, over analyzing every situation and trying to nail down exact triggers was exhausting me.

It wasn’t helping my physical health and was destroying my mental health

At a certain point - we have to accept that chronic illness can be wildly unpredictable - and flares are NOT our fault.

Setbacks happen - and the best thing you can do is give yourself grace and remember that the pain WILL pass.

This applies to Covid as well. I see far too many people who are covid cautious being blamed for their infections. Being grilled as to what their exact precautions were as people try and exploit a perceived weakness somewhere.

This isn’t helping.

If you’re masking and doing everything you can do to avoid covid - you’re doing a great job. If you got infected anyways - that’s the fault of our institutions and governments who’ve allowed the virus to run rampant and encouraged people NOT to take precautions

Just like we have to let go of trying to find every possible trigger for our chronic illness - we have to let go of the blame when people get infected with Covid.

Blame, shame and guilt aren’t helping anyone - and they aren’t good for your health.

To be clear - “letting go” doesn’t have to mean giving up. It doesn’t mean you stop trying to improve your health or stop mitigating for COVID.

It simply means you stop fighting the reality that you’re sick. You lean IN to the conditions and try and find ways to accommodate

It’s a difficult thing to do. I’m still having to work at it every single day. But it’s worth making the effort.

Society, HCWs and even friends & family can be cruel to those with chronic illness - we don’t need to be cruel to ourselves.

Which brings me to my third and final article in my series on living with MCAS - Learning to Let Go.

This post explains how I learned to be kinder & gentler with myself and accept that setbacks WILL happen and they’re not my fault:

disabledginger.com/p/learning-

1/2

The Disabled Ginger · Learning to Let Go - How To Accept Your Chronic IllnessBy Broadwaybabyto

#DisneyWorld says man can’t sue over wife’s death linked to resort #meal as he signed up for Disney

#Disney World has claimed that a man whose wife #died after she suffered a severe #allergic reaction from #dining at the theme park cannot sue because of the terms and conditions he agreed to for a free trial of its TV service … wait for it … in 2019.

telegraph.co.uk/world-news/202

The Telegraph · Disney World says man can't sue over wife's death linked to resort meal as he signed up for Disney+By Kieran Kelly

FDA approves first nasal spray for severe allergic reactions

Neffy is an Rx epinephrine nasal spray for adults and children weighing at least 66 lbs for the treatment of anaphylactic shock.

'...the drug is meant to be available about eight weeks from the FDA approval.

In terms of cost, the fee is about $200 out of pocket.

"For people who are on commercial insurance, the cost is going to be limited to about $25," Gounder said. "And then for people who are underinsured or uninsured, it's going to be made no cost for at least some of them, which is really important, because 40% of kids in the United States are on Medicaid or public insurance.'

cbsnews.com/news/fda-approves-

Will tick-bite allergy, AGS (alpha-gal syndrome), turn us all into vegetarians and help save the planet?

Unlikely. But the deadly disease has been on the rise in the U.S., causing anaphylactic shock in previously healthy people who consume mammal meat and milk after being bitten by the Lone Star Tick (found mostly in the South and Midwest). And most doctors are still ignorant of the disease.

cidrap.umn.edu/tick-borne-dise

www.cidrap.umn.eduCDC: Allergy caused by tick bites on the rise, but clinicians in the darkThe condition is mainly linked to bites from the lone star tick, which are most common in the South and Midwest.

Emerade adrenaline pen users urged to swap brands
The pens are prescribed for people with severe, life-threatening allergies.
The Medicines and Healthcare products Regulatory Agency (MHRA) says users should ask for alternative brands.
bbc.com/news/health-65537820?a
#Emerade #AdrenalinePen #allergies #anaphylaxis

BBC NewsEmerade adrenaline pen users urged to swap brandsUsers of Emerade pens, which treat anaphylaxis, are being warned to change to another brand.