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#Senolytic

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Hao Yin<p>SenMayo<br>A 125-gene set (15 studies) for <a href="https://qoto.org/tags/Senescence" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Senescence</span></a>/#SASP in Bone/Bone marrow/Adipose/Brain...</p><p><a href="https://qoto.org/tags/Senolytic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Senolytic</span></a> readout</p><p>vs GenAge &amp; CellAge</p><p>MIF as a key SASP gene!</p><p>Dr. Dominik Saul, Joshua Farr &amp; Sundeep Khosla labs Nature Comms 2022<br><a href="https://www.nature.com/articles/s41467-022-32552-1" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">nature.com/articles/s41467-022</span><span class="invisible">-32552-1</span></a></p>
Aging Highlights<p>Eliminating Senescent Cells Can Promote Pulmonary Hypertension Development and Progression</p><p><a href="https://mas.to/tags/senescence" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>senescence</span></a> <a href="https://mas.to/tags/Senolytic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Senolytic</span></a> </p><p><a href="https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.122.058794" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">ahajournals.org/doi/10.1161/CI</span><span class="invisible">RCULATIONAHA.122.058794</span></a></p>
Rio Sugimura<p>Elated to be selected as a recipient of @GileadSciences@twitter.com Liver Disease Scholar 2022 <br /><a href="https://med-mastodon.com/tags/LiverDisease" class="mention hashtag" rel="tag">#<span>LiverDisease</span></a> <a href="https://med-mastodon.com/tags/Senolytic" class="mention hashtag" rel="tag">#<span>Senolytic</span></a></p>
Hao Yin<p><a href="https://qoto.org/tags/Senescence" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Senescence</span></a> <a href="https://qoto.org/tags/ImmuneSurveillance" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>ImmuneSurveillance</span></a> <br>Next-gen <a href="https://qoto.org/tags/Senolytic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Senolytic</span></a></p><p><a href="https://qoto.org/tags/ImmuneCheckpointBlockade" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>ImmuneCheckpointBlockade</span></a> activates CD8+ T cytotoxicity against (inflammed🔥) PD-L1+ senescent cells-&gt;<br>⏬adverse phenotypes in🐭<a href="https://qoto.org/tags/Aging" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Aging</span></a>+<a href="https://qoto.org/tags/NASH" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>NASH</span></a></p><p>Dr. Yoshikazu Johmura &amp; Makoto Nakanishi labs Nature 2022<br><a href="https://www.nature.com/articles/s41586-022-05388-4" rel="nofollow noopener noreferrer" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">nature.com/articles/s41586-022</span><span class="invisible">-05388-4</span></a></p>
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