Multiple studies have proven the impact of #endocrine #disruptors, e.g. #phthalates and #parabens, on #thyroid #homeostasis. It was unknown, however, that these effects depend on whether or not the included persons are fasting.
The hazardous impact of #parabens on #thyroid #homeostasis (HPT axis) affects several elements of the feedback loop.
#Formaldehyde And Formaldehyde-Releasing Preservatives
Formaldehyde and formaldehyde-releasing preservatives (#FRPs) are used in many #PersonalCare products, particularly in #shampoos and liquid #BabySoaps.
"These preservatives release small amounts of formaldehyde over time. Since low levels of formaldehyde can cause health concerns-at levels as low as 250 parts per million and even lower levels in sensitized individuals-the slow release of small amounts of formaldehyde are cause for concern. A 2015 study determined that longer storage time and higher temperature increase the amount of formaldehyde released from FRPs and could ultimately lead to more severe health concerns.
"#Quaternium15 is the most sensitizing of these FRPs and is found in #blush, #mascara, #lotion and #shampoo.
"#DMDMHydantoin is found in lotion, #sunscreen and make-up remover and is one of the least sensitizing of the FRPs.
"#ImidazolidinylUrea, #DiazolidinylUrea, and #polyoxymethylene urea, are found in shampoo, conditioner, blush, #EyeShadow, and lotion and are all known human #allergens. #Imidazolidinyl urea is one of the most common #antimicrobial agents used in personal care products and is often combined with #parabens to provide a broad spectrum preservative system. #Diazolidinyl urea releases the most formaldehyde of any FRP.
"Sodium #hydroxymethylglycinate is found in shampoo, moisturizer, conditioner, and lotion. Animal studies have shown that sodium hydroxymethylglycinate has the potential for sensitization and #dermatitis.
"#Bromopol is found in #Nail Polish, #makeup remover, #moisturizer and #BodyWash. Bromopol is considered safe in concentrations less than 0.1%, but cannot be found in formulations with the FRP amine. Mixing bromopol and amines produce #nitrosamines which have been found to penetrate the skin and cause #cancer.
"#Glyoxal is found in conditioner, lotion, nail polish and nail treatment. CIR Expert Panel has declared that glyoxal is a skin allergen.
Regulations
"Banned from use in #cosmetics and #toiletries in #Japan and #Sweden; in the #EU, restricted in personal care products, and labeling is required in products that do contain these chemicals; concentration restrictions in Canada. The EU allows the use of Quaternium-15 up to 0.2% as a preservative in cosmetic products.
How to Avoid?
Read labels and avoid products containing the following ingredients: Formaldehyde, quaternium-15, dimethyl-dimethyl (DMDM) hydantoin, imidazolidinyl urea, diazolidinyl urea, sodium hydroxymethylglycinate, 2-bromo-2-nitropropane-1,3-diol (bromopol). In addition, choose nail products that are labeled formaldehyde-free or “toxic-trio-free” (formaldehyde, toluene and DBP). Skip hair-smoothing products—especially those sold in salons, as salon-based products are exempt from labeling laws. Don’t use expired cosmetic products or store cosmetic products in the sun because this can cause more formaldehyde to be released."
Have you ever heard of #Parabens and wondered what they are and why so many products are advertised as 'paraben-free' these days? Find out the answers and more in my latest article for @theconversationau
Thanks to Sunanda Creagh for being such a great editor.
Just in case my family & I were the only ones who didn't know this about E45 body lotion:
After being recommended we use E45 by a doctor, we have only just realised it contains parabens
Parabens can interfere with our hormone systems and increase breast cancer risk. Source: Breast Cancer UK https://cdn.breastcanceruk.org.uk/uploads/2019/08/Full_brief_parabens_v2_nw.pdf
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