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#anaemia

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Continued thread

Starting with #Health & #nutrition:

Providing school meals would improve the overall diet quality of our kids, potentially reducing rates of #anaemia, #obesity, and other health issues (Verguet et al., 2020).

Assuming #auspol continues to destroy public health care, this is desperately needed as it will reduce the load on the overworked medical staff, shorten waiting times and reverse the predictions of reduced lifetime expectancies of younger generations.

5/n

In 2012 I was 43, and my #weight was just shy of 130kg. I felt like crap, and couldn't keep up with my kid playing kiddy football. I decided to do something about it, started #C25K and a #diet , and by June 2014, I was down to 92kg and was #running 5km three times a week and was well on my way to doing 10km.

Then life threw a curveball and I couldn't #run any more.

And in 2019 I was back to 125kg and was diagnosed with #diabetesT2.

And I started #C25K again, and was back to running 5km a couple of times a week, and was down to about 100kg.

And life threw another curveball, and I couldn't run again. I didn't know it then but my #coeliac gene had activated due to the trauma that stopped me running, and I felt bloody awful. And yup, I ballooned back to ~120kg again. Several utterly useless doctors later "Lose weight and exercise more" "I can barely get off the couch, I am exhausted just walking from the waiting room to your office" "Here's an exercise program" a good #doctor found severe #anaemia as well as #bloating and #JointInflammation and asked why? and I was diagnosed as a #coeliac in November 2023.

I stopped eating #gluten and I slowly lost the feeling of being the walking dead and I started feeling alive again. Very slowly the weight dropped. And I rediscovered the joy of #moving my #body.

Today, I am #55yo , 97kg, and just did this on the #exercise bike, which is 5 minutes longer than when I started a few weeks ago. I'm #purposefully #exercising again.

Will I #run again? Probably not - the #knees and #hips are not what they once were - but I've found that #dancing to #livemusic is great #aerobic #exercise and am happy to hop on the #StationaryBike to make sure I can cope with 2 hours of thrashing it out to #IronMaiden next month. A girl has to have #goals. It's no longer about my #weight or how I #look, it's because #life is short, and I want to #live it.

Wider use of to reduce could benefit patients and health systems | The BMJ bmj.com/content/385/bmj-2024-0 “Because there is strong evidence that tranexamic acid reduces bleeding and transfusion and no indication of any increased risk of thrombosis, the benefits exceed the harms in patients having major surgery. Even in patients who do not require , reducing bleeding will reduce postoperative and facilitate more rapid recovery.”

The BMJ · Wider use of tranexamic acid to reduce surgical bleeding could benefit patients and health systemsIan Roberts and colleagues call for greater use of this inexpensive generic drug that can improve surgical outcomes, avoid unnecessary blood transfusion, and conserve blood stocks Major bleeding during surgery is common and is an important cause of surgical deaths.1 Each year, worldwide, over 300 million people have major surgery, and around four million die within 30 days of the operation.2 In the UK, there are eight million surgical procedures each year with about 85 000 deaths within 30 days.3 Major bleeding is strongly associated with mortality, accounting for the largest share of deaths.1 Transfusion can be lifesaving, but blood is a scarce resource and transfusion has risks. The strong evidence that tranexamic acid safely reduces surgical bleeding and the need for blood transfusion therefore has important implications for patient care, not only in the UK but worldwide. In the UK the National Institute for Health and Care Excellence (NICE) made the use of tranexamic acid for adults who are having surgery and expected to have “moderate (>500 ml) blood loss” a quality standard in 2016.4 However, according to a 2023 NHS national comparative audit, at least one third of surgical patients in England who should receive tranexamic acid are not treated.5 We estimate that half a million surgical patients in the UK miss out on the benefits of tranexamic acid. Full compliance with the NICE quality standard would prevent about 15 000 major surgical bleeds, avoid the transfusion of 33 000 units of blood, and save 45 000 hospital days and millions of pounds for the NHS each year.6 High rates of non-use of tranexamic acid have also been found in Australia and New Zealand.7 Clinical audit also shows a wide variation in tranexamic acid use by different surgical specialties.5 Tranexamic acid is most …

Dr Liu said the "therapeutic applications of base editing are just beginning" and it was "humbling to be part of this era of therapeutic human #gene editing", as #science was now taking "key steps towards taking control of our genomes". #cancer #leukaemia #Chemotherapy #genetics #health #anaemia bbc.co.uk/news/health-63859184

BBC NewsBase editing: Revolutionary therapy clears girl's incurable cancerNew way of altering DNA is used to engineer an "exciting", experimental therapy for a 13-year-old girl.