und die kommt bei euch immer sehr gut an, die Zottige Haarschnecke Trochulus villosus.
die hier war noch sehr klein, vllt 5 millimeter hausdurchmesser
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#snail
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Friend in the dunes, while waiting for sunset on Holywell Bay I spent some time chasing the snails that live amongst the dunes. #photography #cornwall #holywellbay #snail #lumix
"Structural similarities reveal an expansive conotoxin family with a two-finger toxin fold"
https://www.biorxiv.org/content/10.1101/2025.07.03.662903v1?rss=1
#DrosophilaMelanogaster
#Evolution
#Drosophila #Snail
bioRxiv · Structural similarities reveal an expansive conotoxin family with a two-finger toxin foldVenomous animals have evolved a diverse repertoire of toxins with considerable pharmaceutical potential. The rapid evolution of peptide toxins, such as the conotoxins produced by venomous marine cone snails, often complicates efforts to infer their evolutionary relationships based solely on sequence information. Structural bioinformatics, however, can provide robust support. Here, we first solve the NMR structure of a macro-conotoxin from the MLSML superfamily, Tx33.1, which is composed of 124 residues, including 12 cysteines. We then apply deep learning-based methods for structure prediction and comparison to identify structural similarities between this toxin and five additional, previously uncharacterized conotoxin superfamilies. Although only three of these superfamilies exhibit sequence homology, a combined approach incorporating structure prediction, structure comparison, and gene structure analysis supports the conclusion that all six superfamilies share a common evolutionary past. The Tx33.1 NMR structure displays similarity to the first two domains of Argos, a secretory protein from Drosophila melanogaster that comprises three domains, each harboring two short β-stranded loops ('fingers'). Consequently, we propose the name 'two-finger toxin (2FTX)' fold for this type of domain. Finally, using structure similarity searches, we identify a wide range of 2FTX proteins in protostomes, including non-venom-derived, secretory cone snail proteins. This study demonstrates how structural bioinformatics can be employed to uncover evolutionary relationships among rapidly evolving genes. It simultaneously identifies a large, previously unrecognized group of protostome 2FTX proteins, many of which exhibit close structural similarity to Argos and may perform a similar function in regulating EGFR signaling.
### Competing Interest Statement
The authors have declared no competing interest.
Novo Nordisk Foundation, NNF21OC0071079, NNF18OC0032996
National Institutes of Health, https://ror.org/01cwqze88, GM144719, R35 GM136430
Independent Research Fund Denmark, 3102-00006B
Garden Snail (Cornu aspersum)
An interloper on the black currants.
A very shonky photo of a snail on my blackcurrant bush, I was trying to take the phone photo one handed while holding the currant stem in my other hand.
#snail
#InMyGarden
Teeny tiny snail!
#snail
No more daylily but plenty of #snail
A rusty 
for #fotovorschlag "Schnecken / Snails"
Coiling for #fotovorschlag "Schnecken / Snails"
Okay, so this may be cheating - but it is snail adjacent
! This is the view up the spiral staircase in Palazzo Boncompagni. In Italian, a spiral staircase is called a "Scala a chiocciola" and "chiocciola" is the word for snail (and the @ symbol)! 
#photography #amateurphotography #building #architecture #urban #city #stairs #staircase #snail #spiral #dark #moody #shape #buildingphotography #urbanphotography #palazzo #travel #bologna #italy #italia #europe
for #fotovorschlag "Schnecken / Snails" Okay, so this may be cheating - but it is snail adjacent
! This is the view up the spiral staircase in Palazzo Boncompagni. In Italian, a spiral staircase is called a "Scala a chiocciola" and "chiocciola" is the word for snail (and the @ symbol)! #photography #amateurphotography #building #architecture #urban #city #stairs #staircase #snail #spiral #dark #moody #shape #buildingphotography #urbanphotography #palazzo #travel #bologna #italy #italia #europe
'Schnecken' #fotovorschlag
Eine kleine Haarschnecke (Trochulus hispidus).
#fotovorschlag 'Schnecken'
Kartäuserschnecke an Knäuelgras, Juli 2024
Monacha cartusiana on Dactylis glomerata
#nature #naturephotography #green #natur #naturfotografie #snail #silentsunday #schnecke #gräser #sommer #grass #summer
Kartäuserschnecke an Knäuelgras, Juli 2024
Monacha cartusiana on Dactylis glomerata
#nature #naturephotography #green #natur #naturfotografie #snail #silentsunday #schnecke #gräser #sommer #grass #summer
#FotoVorschlag: #Schnecken // #Snails
Jetzt muss ich doch noch ein Foto nachreichen, weil ich bei den vielen Bildern hier an meinen Lieblingszungenbrecher denken muss: // I have to post another one because all the #snail photos remind me of my favourite German tongue twister:
𝘚𝘤𝘩𝘯𝘦𝘤𝘬𝘦𝘯 𝘦𝘳𝘴𝘤𝘩𝘳𝘦𝘤𝘬𝘦𝘯, 𝘸𝘦𝘯𝘯 𝘴𝘪𝘦 𝘢𝘯 𝘚𝘤𝘩𝘯𝘦𝘤𝘬𝘦𝘯 𝘴𝘤𝘩𝘭𝘦𝘤𝘬𝘦𝘯, 𝘸𝘦𝘪𝘭 𝘻𝘶𝘮 𝘚𝘤𝘩𝘳𝘦𝘤𝘬𝘦𝘯 𝘷𝘪𝘦𝘭𝘦𝘳 𝘚𝘤𝘩𝘯𝘦𝘤𝘬𝘦𝘯 𝘚𝘤𝘩𝘯𝘦𝘤𝘬𝘦𝘯 𝘯𝘪𝘤𝘩𝘵 𝘴𝘤𝘩𝘮𝘦𝘤𝘬𝘦𝘯.
(A literal translation would be "Snails are shocked when they lick snails because to the dismay of many snails, snails don’t taste good." 
)
#Schnecke #Nacktschnecke #HainBänderschnecke #slug #landSnail #landSnails #mollusk #Moos #moss #mosstodon #Trendelburg #Wülmersen #Weserbergland #nature #Natur #animal #Tier #animalPhotography #tongueTwister #Zungenbrecher #snailsOfMastodon
Jetzt muss ich doch noch ein Foto nachreichen, weil ich bei den vielen Bildern hier an meinen Lieblingszungenbrecher denken muss: // I have to post another one because all the #snail photos remind me of my favourite German tongue twister:
𝘚𝘤𝘩𝘯𝘦𝘤𝘬𝘦𝘯 𝘦𝘳𝘴𝘤𝘩𝘳𝘦𝘤𝘬𝘦𝘯, 𝘸𝘦𝘯𝘯 𝘴𝘪𝘦 𝘢𝘯 𝘚𝘤𝘩𝘯𝘦𝘤𝘬𝘦𝘯 𝘴𝘤𝘩𝘭𝘦𝘤𝘬𝘦𝘯, 𝘸𝘦𝘪𝘭 𝘻𝘶𝘮 𝘚𝘤𝘩𝘳𝘦𝘤𝘬𝘦𝘯 𝘷𝘪𝘦𝘭𝘦𝘳 𝘚𝘤𝘩𝘯𝘦𝘤𝘬𝘦𝘯 𝘚𝘤𝘩𝘯𝘦𝘤𝘬𝘦𝘯 𝘯𝘪𝘤𝘩𝘵 𝘴𝘤𝘩𝘮𝘦𝘤𝘬𝘦𝘯. (A literal translation would be "Snails are shocked when they lick snails because to the dismay of many snails, snails don’t taste good."
)#Schnecke #Nacktschnecke #HainBänderschnecke #slug #landSnail #landSnails #mollusk #Moos #moss #mosstodon #Trendelburg #Wülmersen #Weserbergland #nature #Natur #animal #Tier #animalPhotography #tongueTwister #Zungenbrecher #snailsOfMastodon
#FotoVorschlag 'Schnecke' sagt:
Ich habe gestern ein Glühwümchen verschluckt 
Nun kann ich abends noch im Ratgeber "Wie werde ich 100 Jahre alt" weiterlesen und in mein Schneckchen-Tagebuch ein paar Zeilen schreiben.
@FotoVorschlag
'Schnecken' / 'Snails'
#FotoVorschlag: #Schnecken // #Snails
Wie schön, die wollte ich euch schon länger zeigen!
Ich dachte erst, die arme #Schnecke wäre verletzt oder deformiert, aber dann habe ich festgestellt, dass das eine Art ist, die ich noch gar nicht kannte: ein #Steinpicker! 
// Oh, nice! I've wanted to show you this #snail for a while now! First I thought the poor thing was hurt or deformed, but then I realized it's a species I have never heard of: a lapidary snail!
#Schnirkelschnecken #Schnirkelschnecke #landSnail #landSnails #mollusk #Moos #moss #mosstodon #stoneWall #Steinmauer #Trendelburg #Wülmersen #Weserbergland #nature #Natur #animal #Tier #animalPhotography #snailsOfMastodon #Helicidae #lapidarySnail #HelicigonaLapicida
Wie schön, die wollte ich euch schon länger zeigen!
Ich dachte erst, die arme #Schnecke wäre verletzt oder deformiert, aber dann habe ich festgestellt, dass das eine Art ist, die ich noch gar nicht kannte: ein #Steinpicker! // Oh, nice! I've wanted to show you this #snail for a while now! First I thought the poor thing was hurt or deformed, but then I realized it's a species I have never heard of: a lapidary snail! #Schnirkelschnecken #Schnirkelschnecke #landSnail #landSnails #mollusk #Moos #moss #mosstodon #stoneWall #Steinmauer #Trendelburg #Wülmersen #Weserbergland #nature #Natur #animal #Tier #animalPhotography #snailsOfMastodon #Helicidae #lapidarySnail #HelicigonaLapicida