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#birdflubegins

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Strangely reassured by statistic that over two in five Usians don't believe our SARS pandemic is over.

Strangely reassured by statistic that two in five Usians recognize that life will never get "back to normal".

Less reassured that near three in ten Usians believe they haven't been infected. Nowhere near that many are taking precautions, so belief is just that.

Still less reassured that none of these statistics in any way reflect preparedness for our pending H5N1 pandemic.

Genotype map of HPAI #H5N1, via GISAID.

"Showing 137 of 137 genomes collected between Dec 2020 and Feb 2025, last updated 2025-02-23"

To be clear, GISAID originally stood for "Global Initiative on Sharing Avian Influenza Data".

Also, as a reminder, there was a different Usian president in office for the period from late January 2021 to early Jan 2025.

Took four years for the global initiative for sharing avian influenza data to collect 137 North American #BirdFlu samples, include dairy cow, avian, human, guineafowl, other mammals, chicken and pheasant.

By comparison, #CDC has tested ~136,000 specimens (about 800 of those humans). Sounds like a lot, right?

That's across 166 Million affected poultry and near a thousand dairy herds. (Current cattle herd numbers reflect anywhere from 1 to 30 cases in three states.)

Pathetic.

Without sequence data, there's no way to reliably track evolution of the virus. Statistical samples don't work from happenstance.

Continued thread

To put recent news—of #influenza deaths exceeding #covid deaths—in context, #CDC now has preliminary #flu burden estimates for season ended Sept 2024.

#PublicHealth surveillance systems have never been adequate for tracking flu, so CDC uses models to arrive at estimates.

By comparison, covid mortality reflects actual deaths reported as due to covid. There's no comparable covid burden modeling being done, so covid deaths believed misreported—as "natural causes" or otherwise—don't show up in this figure.

End of last flu season, annualized covid mortality was more than double estimated influenza burden deaths.

Covid death reporting began sharp deceleration in December, after spike in July/August. Such drop-off in reporting must be taken into account when comparing mortality stats.

Won't likely see flu burden estimates for this new season until early next year. But we know non-#BirdFlu flu is stressing hospitals, and #H5N1 cases have gone unrecognized.

Continued thread

Of course, outdoor cats also kill and eat wild birds, or else bring them home as gifts, so there could be a more direct line of transmission.

But for the variants specifically adapted to mammals, escape by way of mammalian carriers—interfacing with concentrated industrial bioreactor facilities—is still gonna be part of this.

Continued thread

They caught this case, even if it did get immediately redacted from public record.

But not everyone who gets bird flu is gonna recognize it as bird flu. If it comes to them through a chain of transmission from farms to feral cats to outdoor cats, an entire household might come down with a nasty "flu".

If it doesn't hospitalize any of them immediately, no one will think anything of it—because their suburban or exurban community ain't in farm country. Kids get pink eye all the time.

So they'll walk around, relying on OTC remedies, spreading it to neighbors and co-workers and schoolmates and fellow shoppers in the drug store aisle.

And only when hospitals—already short on staff—see it in E/Rs and wards, as more vulnerable neighbors start dropping, will there be actual patients to swab and sequence.

And again, we knew about this April of last year! The redactions in February of 2025 are what they are, but we knew about this during the prior administration!

Same #CDC.

Continued thread

Oh, me?

Just sitting here, wondering how much GISAID data for the U.S. there will be from late January forward. (Raj's dashboard last shows data through the 17th.)

Aware that #CDC long ago would have preferred to stop publishing #covid variants estimates, am expecting to not see same updated this Friday.

They stopped publishing all other related data long before now, and still weren't publishing anything useful wrt #BirdFlu, as of close of last administration.

So now we wait to see how much compliance in advance impacts academic researchers submitting data to a global non-profit. (Let alone how much of U.S. GISAID data may be typically provided by gov't researchers.)

Yes, GISAID was founded in opposition to WHO's proprietary data practices. But also, GISAID's public domain ethos is close enough in spirit to F/OSS that it might just as readily be a target of isolationist fervor.

So, it's wait in see.

Of course, a muzzle defied doesn't necessarily stop at the agency.

Nothing any government agency has to say gets anywhere without cooperation of news media or media platforms.

"No communication with the public" may be acceptably interpreted to carve-out certain categories of alerts.

(Carve-outs that wouldn't have been readily apparent until lawyers got a chance to ponder them in the days after the moratorium.)

But as soon as it becomes clear that communication with the public is happening beyond tolerated boundary conditions, a quiet word to a sympathetic media owner, or else a subtle message to someone in middle management about their future prospects in the job market, would be all it would take.

Nor does it even need start with the political chief. If we know anything, it is that heads of petty fiefdoms will readily, over-enthusiastically and without explicit direction, enforce what they believe the will of the sovereign to be.

Sitting with the uncomfortable certainty that most health supremacist Usians may never notice that federal public health officials aren't communicating with the public.

Given that our health supremacist society had already become accustomed to, scratch that, come to rely upon, near four years of public health agencies only communicating purposeful nonsense—and the same culture has been further stubbornly ignoring any genuine information that somehow slipped through the mass apologetics—silence ain't gonna likely get the typical health supremacist's attention.

Not until it's bewilderingly too late.

"As an avian influenza virus (AIV) panzootic is underway, the threat of a human pandemic is emerging. Infections among mammalian species in frequent contact with humans should be closely monitored. One mammalian family, the Felidae, is of particular concern. Domestic cats are susceptible to AIV infection and provide a potential pathway for zoonotic spillover to humans. Here, we provide a systematic review of the scientific literature to describe the epidemiology and global distribution of AIV infections in felines reported from 2004 – 2024."

medrxiv.org/content/10.1101/20

HT Daniele Focosi on X

medRxiv · Avian Influenza Virus Infections in Felines: A Systematic Review of Two Decades of LiteratureAs an avian influenza virus (AIV) panzootic is underway, the threat of a human pandemic is emerging. Infections among mammalian species in frequent contact with humans should be closely monitored. One mammalian family, the Felidae, is of particular concern. Domestic cats are susceptible to AIV infection and provide a potential pathway for zoonotic spillover to humans. Here, we provide a systematic review of the scientific literature to describe the epidemiology and global distribution of AIV infections in felines reported from 2004 – 2024. We identified 607 AIV infections in felines, including 302 associated deaths, comprising 18 countries and 12 felid species. We observed a drastic flux in the number of AIV infections among domestic cats in 2023 and 2024, commensurate with the emergence of H5N1 clade 2.3.4.4b. We estimate that this phenomenon is underreported in the scientific literature and argue that increased surveillance among domestic cats is urgently needed. ### Competing Interest Statement The authors have declared no competing interest. ### Funding Statement We acknowledge the support of the University of Maryland Baltimore, Institute for Clinical & Translational Research (ICTR) and the University of Maryland Strategic Partnership: MPowering the State (MPower) to KKC, as well as discretionary funding from the University of Maryland School of Public Health, Department of Global, Environmental, and Occupational Health to KKC. ### Author Declarations I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained. Yes I confirm that all necessary patient/participant consent has been obtained and the appropriate institutional forms have been archived, and that any patient/participant/sample identifiers included were not known to anyone (e.g., hospital staff, patients or participants themselves) outside the research group so cannot be used to identify individuals. Yes I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov. I confirm that any such study reported in the manuscript has been registered and the trial registration ID is provided (note: if posting a prospective study registered retrospectively, please provide a statement in the trial ID field explaining why the study was not registered in advance). Yes I have followed all appropriate research reporting guidelines, such as any relevant EQUATOR Network research reporting checklist(s) and other pertinent material, if applicable. Yes All data produced in the present study are available upon reasonable request to the authors.

"#H5N1, a disease typically only found in wild birds, has been killed seals and sea lions in the tens of thousands. Dairy cattle have been seeing lying dead in the sun in California. AND we know that the strain this person was infected with was the same strain as the teenager hospitalized in British Columbia— and that one has the gene necessary for human to human transmission. Even so, the rhetoric of the CBS newscast sampled here said the danger to the general public is very low. I would laugh if this wasn’t such a disaster."

instagram.com/reel/DDx0V3HvmYb

Instagramismatu on Instagram: "H5N1, a disease typically only found in wild birds, has been killed seals and sea lions in the tens of thousands. Dairy cattle have been seeing lying dead in the sun in California. AND we know that the strain this person was infected with was the same strain as the teenager hospitalized in British Columbia— and that one has the gene necessary for human to human transmission. Even so, the rhetoric of the CBS newscast sampled here said the danger to the general public is very low. I would laugh if this wasn’t such a disaster. Now? NOW it’s severe?"25K likes, 330 comments - ismatu.gwendolyn on December 19, 2024: "H5N1, a disease typically only found in wild birds, has been killed seals and sea lions in the tens of thousands. Dairy cattle have been seeing lying dead in the sun in California. AND we know that the strain this person was infected with was the same strain as the teenager hospitalized in British Columbia— and that one has the gene necessary for human to human transmission. Even so, the rhetoric of the CBS newscast sampled here said the danger to the general public is very low. I would laugh if this wasn’t such a disaster. Now? NOW it’s severe?".

Was watching some old popular audience wish fulfillment television the other day. The story was about a group of unlikely heroes who foil a plot to release an aerosol pandemic virus into the general population.

The villain-of-the-week started by trying to kill heads of institutions that would be tasked with responding to such an outbreak.

Later that day, saw this news: "Ghebreyesus said he and other WHO colleagues were preparing to board a flight just "meters" away from the area Israel hit."

Ghebreyesus is head of the World Health Organization. Israel, who received arms supplies from the U.S., bombed the airport he was preparing to depart from.

National voluntary recall of cat foods because #BirdFluBegins.

As influenza surge making news in various Usian cities.

Of course, #H5N1 is an influenza.

At some point, #BirdFlu is gonna make the leap to full adaptation for inter-human transmission.

If it happens during a post-holiday winter surge, we might not even know we're dealing with zoonotic spillover, because flu looks like flu until you bother to sequence.

Unless you bother to sequence.

(Also, lots of other things look like flu, but we can at least tell covid and RSV, when we bother to test, from flu.)

As of December, two in five Usians have been vaccinated for seasonal flu. The lowest uptake in the past six years.

Meanwhile, our government continues to arm a rogue national government that bombs an airport while the head of the world's global health agency is on the tarmac.

If the world suffers a #BirdFlu pandemic in the years immediately following this coming #Jan20...

Please remember that the previous administration had more than enough opportunities to address the #H5N1 threat on the horizon, long before even the absurdly drawn-out U.S. electoneering cycle began.

Usian partisans will want ya'll to blame global mortality of a pandemic in the second half of this decade on the person then in office...

Rather than on the naked emperor, who ensured that there be no serious interventions to stop spread and mutation in U.S. livestock—lest attention to such distract from boasting about ending a pandemic, from the first half of this decade, that still has yet to end.

Nero doesn't get to blame Galba, just because the second conflagration was slow to start.