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Some evidence type I IFN being beneficial in airway infections.
But lots of caveats, context-specific issues, mouse models, etc....
#IFN #Interferon #bacteria #infection #MAIT #immunology #Science @JExpMed
https://rupress.org/jem/article/220/10/e20230037/276132/Type-I-interferons-drive-MAIT-cell-functions?guestAccessKey=9a754261-0c2a-4913-b3b7-d98c2395c025&utm_source=NewJournalContent%27&%27utm_campaign%27=%27JEM%27&%27utm_medium%27=%27Email&nbd=28080031447&nbd_source=campaigner&_ccCt=g843-2pnqf6-cox1lz-cwe4ixj5
rupress.orgType I interferons drive MAIT cell functions against bacterial pneumonia | Journal of Experimental Medicine | Rockefeller University PressThis report identifies a central role for type I interferons in governing the activation and effector functions of murine and human MAIT cells during pulmonary