I wrote about the new anti-obesity drugs—semaglutide (Wegovy) and tirzepatide (Mounjaro)—that represent one of the most important breakthroughs in medicine
https://erictopol.substack.com/p/the-new-obesity-breakthrough-drugs
@erictopol as you note, the potential lifetime cost of #semaglutide and #tirzepatide is a massive issue. Benefits for CV disease would be helpful, but as yet unproven for this population and at these doses. Let’s also not forget about #MetabolicSurgery which has clinical benefit on life expectancy, CV disease, cancer etc.