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open.substack.com/pub/insideme “Brand new high-quality data indicate that (the generic name for the blockbuster diabetes and obesity medication ) is effective in improving symptoms of a certain hard-to-treat type of . The just-released study—a double-blinded placebo-controlled randomized clinical trial of obese adults—appears in the New England Journal of Medicine.”

Inside MedicineBreaking news: Semaglutide (“Ozempic”) effectively treats heart failure. Why that is a big, huge, deal. By Jeremy Faust, MD

“In patients with with preserved ejection fraction and , treatment with (2.4 mg) led to larger reductions in symptoms and physical limitations, greater improvements in exercise function, and greater weight loss than placebo.”

nejm.org/doi/full/10.1056/NEJM