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Auscandoc

sends about half a million children to emergency departments in the U.S. every year; somewhere between 58,000 and 80,000 of those children end up being hospitalized. The estimates that between 100 and 300 children die from RSV in any given year.

In a Phase 3 clinical trial, the Pfizer was shown to reduce the risk of severe disease caused by RSV by 82% at three months after birth and 69% at six months.” scicomm.xyz/@HelenBranswell/11

A community for scientists and science communicators.Helen Branswell (@HelenBranswell@scicomm.xyz)#RSV is a horrible infection in young kids. With this vaccine and AstraZeneca & Sanofi's monoclonal antibody, the tide could be changing. https://www.statnews.com/2023/08/21/pfizer-rsv-vaccine-abrysvo-newborns-fda-approval/

@auscandoc Yes, this can be a great first stup! But I doubt this will be a magic bullet. The trial showed non-sign (less good) efficacy in infants <3 months, this vulnerable group (needing lots of in-hospital care in my experience) needs something that works better.

@stefanjohansson Yes. Helen mentioned some of these caveats in her article. I’m also wary of the non significant trend towards premature delivery. We need to see if, in a rollout into a larger population, this become significant.

As well as the possible dampening effect on other vaccines. 🤷‍♂️