Prolonged nicotine exposure, via electronic cigarette, selectively increases Bdnf/TrkB transcription, dynorphin peptide levels and OLIG2 in male rat VTA
Prolonged nicotine exposure, via electronic cigarette, selectively increases Bdnf/TrkB transcription, dynorphin peptide levels and OLIG2 in male rat VTA
Pharmacokinetic/pharmacodynamic evaluation of ublituximab in patients with autoimmune diseases
https://euclinicaltrials.eu/search-for-clinical-trials/?lang=en&EUCT=2023-509555-13-00
Pregnancy Registry, Infants, Serum/Milk Analysis (PRISMA)
https://clinicaltrials.gov/study/NCT06940323?cond=Multiple+Sclerosis
An open-label, multi-center, phase I/II study to assess safety, disease progression, and cellular kinetics following YTB323 administration in participants with non-active Progressive Multiple Sclerosis (PMS)
https://euclinicaltrials.eu/search-for-clinical-trials/?lang=en&EUCT=2024-514006-31-00
Universal Chimeric Antigen Receptor T-Cell (UCAR T-cell) Therapy Targeting CD19/B Cell Maturation Antigen (CD19/BCMA) in Patients With r/r Neurological Autoimmune Diseases
https://clinicaltrials.gov/study/NCT06939166?cond=Multiple+Sclerosis
Tripterygium glycoside tablets and triptolide alleviate experimental autoimmune encephalomyelitis mice involving the PACAP/cAMP signaling pathway
An open-label, multi-center, phase 1/2 study to assess safety, efficacy, and cellular kinetics of YTB323 in participants with Relapsing Multiple Sclerosis with breakthrough disease activity during previous treatment with a highly efficacious therapy
https://euclinicaltrials.eu/search-for-clinical-trials/?lang=en&EUCT=2024-512714-18-00
MALAT1 promotes microglia activation and neuronal apoptosis through via the miR-124-3p/ SGK1 axis mediating experimental autoimmune encephalomyelitis disease progression in mice
Amyloid‐β Dysregulates Oligodendroglial Lineage Cell Dynamics and Myelination via <scp>PKC</scp> in the Zebrafish Spinal Cord
A Study of LCAR-AIO CAR-T Cells for Treating Relapsed/Refractory Neurological Autoimmune Diseases
https://clinicaltrials.gov/study/NCT06869278?cond=Multiple+Sclerosis
Pectolinarin Promotes Functional Recovery after Spinal Cord Injury by Regulating Microglia Polarization Through the PI3K/AKT Signaling Pathway
Effect of ozanimod on meningeal inflammation and glial activation in Multiple Sclerosis: one year phase 4 experimental study
PROTOCOL CODE: OZA22 / IM047 - 048
https://euclinicaltrials.eu/search-for-clinical-trials/?lang=en&EUCT=2024-518859-27-00
A 96-Week, Prospective, Multicenter, Randomised, Double-Blind, Placebo-Controlled, Phase 3 Study to Compare Efficacy and Safety of Masitinib Dose Titration to 4.5 mg/kg/day versus Placebo in the Treatment of Patients with Primary Progressive or Secondary Progressive Multiple Sclerosis Without Relapse
https://euclinicaltrials.eu/search-for-clinical-trials/?lang=en&EUCT=2024-516672-16-00
Norepinephrine (NE) promotes activated B cells to identify and kill effector CD8+ T cells through FasL/Fas pathway in spleen mononuclear cells isolated from experimental autoimmune encephalomyelitis (EAE)