https://www.europesays.com/uk/26670/ Ozempic Linked to Lower Alzheimer’s Risk #Alzheimer'sDisease #BrainResearch #GLP1 #Health #neurobiology #Neurology #neuropharmacology #Neuroscience #Ozempic #UK #UnitedKingdom #UniversityOfFlorida #Wegovy

New Review and Meta-Analysis confirms weight gain with discontinuance of #Semaglutide and #Tirzepatide

Discontinuing GLP1 medications led to a pooled overall mean weight regain of 9.69 kg (or about 22 lbs in patients prescribed semaglutide/tirzepatide. The proportion of weight regained was proportional to the amount originally lost.

Discontinuation of GLP-1RA treatment leads to weight regain, regardless of lifestyle interventions, and should therefore be considered a chronic therapy to prevent weight regain and associated undesirable outcomes related to #Obesity.

#wegovy #ozempic #mounjaro #zepbound
https://onlinelibrary.wiley.com/doi/10.1111/obr.13929

#ozempic #wegovy experiences for weight loss please. for a man not in his 30's any more. Worth it? Aussie prescription or order from dodgy overseas mart?

GLP-1s Are Crazy Effective — Just Not Cost-Effective

I’ll make the argument that the most effective drugs in the past decade are the GLP-1 receptor agonists, drugs like semaglutide and tirzepatide. At least in terms of weight loss, they are truly unparalleled. They are clearly effective. But are they worth it? Are they cost-effective? That is a much harder question, and, as you’ll see in a minute, despite their amazing effects, the answer — for now, at least — is no.

#mounjaro #ozempic #zepbound #wegovy #glp1
https://www.medscape.com/viewarticle/glp-1s-are-crazy-effective-just-not-cost-effective-2025a10006es?form=fpf

Novo Nordisk slashes Wegovy price for patients lacking insurance benefits — https://www.washingtonpost.com/business/2025/03/05/novo-nordisk-wegovy-cash-discount/
#HackerNews #Novo #Nordisk #Wegovy #price #insurance #discount #healthcare #access

https://archive.ph/05BVi #glp1 #wegovy #ozempic #zepbound #monjauro #diet

After years in Big Pharma, a chemist pivoted to help save the species that made weight-loss drugs possible.
#giftarticle #biodiversity #nature #ozempic #wegovy #pharma

https://www.nytimes.com/2025/02/16/science/gila-monsters-cryptosporidium.html?unlocked_article_code=1.xU4.s5dC.9VnBea8q1g_g&smid=url-share

State budgets are under pressure from the growing demand for GLP-1 weight-loss drugs like #Ozempic and #Wegovy. As coverage decisions loom, states balance cost savings with long-term health benefits. How do we find the right balance? #PublicHealth #HealthcareCosts https://www.politico.com/news/2025/02/12/ozempic-state-budgets-00202932

Would fen-phen have been banned by today's FDA? Has regulatory capture reached the invulnerable pharmaceutical corp stage, yet?

We'll find out by how long it takes Wegovy / Ozempic to get banned.

A drug that claims to cure obesity is taking over the market and people’s minds. Is semaglutide a miracle or a dangerous trap? It was made for diabetics, but now everyone’s using it—without asking what the real price might be. Some say it’s the new radium, once hyped as a cure-all. While celebrities show off their weight loss, scientists keep finding new side effects. So, is it really worth it?

https://lab66.substack.com/p/ozempic

The system "was built to keep us sick and stuck," telehealth company Hims says in a Super Bowl ad (over Childish Gambino's "This Is America"!)

But experts point out that the ad uses criticism of companies "selling weight loss drugs...to then themselves sell weight loss drugs."

via @STAT
https://www.statnews.com/2025/01/28/super-bowl-ad-hims-and-hers-telehealth-company-downplays-risks-compounded-drugs/

GLP-1 drugs like #Ozempic may lower the risk of 42 health conditions, including Alzheimer's, dementia, and substance use disorders—but raise risks for 19 others. A doctor-scientist explains the latest study: https://buff.ly/40tknK3 #weightloss #wegovy #mounjaro

Weight-loss jabs could be linked to lower risk of several conditions including stroke and dementia | The Independent
https://www.independent.co.uk/news/health/weight-loss-jabs-drugs-benefits-ozempic-wegovy-b2683404.html

#Ozempic
#Wegovy
#Stroke
#Dementia

I know FOR A FACT that I posted this story when it broke that Pres. #Biden added #Ozempic ($997/dose), #Wegovy ($1,300/dose) and 13 other wildly costly prescription drugs to the list of medicines #Medicare will now be allowed to negotiate the price on, but now I can't find it.

(Found it. I had included it in my Update of #Biden's final statistics.)

GLP-1s like #Ozempic, #Saxenda, #Wegovy, or #Mounjaro are not an easy #weightloss hack.

Find out more about:
what they are
how they're used
who they help

Learn more: https://youtu.be/mTlbRxEpD5s
---
https://nitter.privacydev.net/EMA_News/status/1875474754552889431#m

It's a start. There is some debate as to whether this will increase or reduce drug prices for other insurance plans.

https://www.nbcnews.com/health/health-news/medicare-drugs-price-negotiations-ozempic-rcna187937

When one year’s sales matches a full three decade research budget,
#price #gouging is clearly afoot.

And that’s the case for Novo Nordisk A/S,
-- maker of sister GLP-1 drugs #Ozempic (type 2 diabetes, T2D)
and #Wegovy (obesity).

In September, Bloomberg estimated that the two drugs would bring in $65 billion in sales by the end of 2024.

The entire research budget for the past three decades is $68 billion, with the company stating that its R&D budget for 2023 was only $5 billion or about 7% of sales in 2024.

News reports note that Novo Nordisk charges US patients about $1,000 per month for Ozempic
and almost $1,400 for Wegovy.

Currently, insurance provides coverage when described for T2D but not obesity.

Given that obesity is a risk factor for T2D, this decision seems shortsighted; but that’s for another day.

In its home country of Denmark, Novo Nordisk reduced the price for Ozempic under governmental pressure by a third.

It’s now costs the government $130 a month in Denmark for patients with T2D.

Wegovy is not covered by the state health care plane and would cost Denmark patients $365 out of pocket per month.

Ozempic price in Germany? -- $92 a month.

That’s 10-fold price premium for Ozempic in the US when compared with Germany.

Yet researchers estimate that Ozempic could be produced for $5 a month, or less, including a profit margin.

This is an oligopolistic market, and as such it should be regulated.

Three firms — Novo Nordisk, Eli Lilly, and Sanofi — “control more than more than 90% of the global insulin market.”

These GLP-1 drugs fall into the insulin market due to their impact on diabetes;

many patients are able to reduce or stop insulin when taking Ozempic
https://themoderatevoice.com/past-time-to-regulate-big-pharma-novo-nordisk-profits-in-2024-are-obscene/