A #placental model of #SARSCoV2 infection reveals ACE2-dependent susceptibility and differentiation impairment in #syncytiotrophoblasts | Nature Cell Biology https://www.nature.com/articles/s41556-023-01182-0 “We identified that syncytiotrophoblasts could be infected through angiotensin-converting enzyme 2 (#ACE2). Using a co-culture model of vertical transmission, we confirmed the ability of the virus to infect syncytiotrophoblasts through a previous endometrial cell infection.”
NatureA placental model of SARS-CoV-2 infection reveals ACE2-dependent susceptibility and differentiation impairment in syncytiotrophoblasts - Nature Cell BiologyChen, Neil, Tan, Rudraraju et al. use an induced trophoblast stem-cell-based model of SARS-CoV-2 infection and identify syncytiotrophoblasts as the cells targeted by the virus in the early placenta.