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Scientific EuropeanQfitlia (Fitusiran): A Novel siRNA-based Treatment for Haemophilia   Qfitlia (Fitusiran), a novel siRNA-based treatment for haemophilia has received FDA approval............ <a href="https://toot.community/tags/Bleedingdisorders" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Bleedingdisorders</a> <a href="https://toot.community/tags/FDA" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#FDA</a> <a href="https://toot.community/tags/Fitusiran" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Fitusiran</a> <a href="https://toot.community/tags/Haemophilia" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Haemophilia</a> <a href="https://toot.community/tags/Hemophilia" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Hemophilia</a> <a href="https://toot.community/tags/Qfitlia" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Qfitlia</a> <a href="https://toot.community/tags/siRNA" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#siRNA</a> Umesh Prasad <a href="https://www.scientificeuropean.co.uk/medicine/qfitlia-fitusiran-a-novel-sirna-based-treatment-for-haemophilia/" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.scientificeuropean.co.uk/medicine/qfitlia-fitusiran-a-novel-sirna-based-treatment-for-haemophilia/</a>

CellBioNewsProtecting <a href="https://scientificnetwork.de/tags/crops" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#crops</a>: <a href="https://scientificnetwork.de/tags/RNA" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#RNA</a>-based substances open up new avenue to combat a widespread <a href="https://scientificnetwork.de/tags/plant" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#plant</a> <a href="https://scientificnetwork.de/tags/virus" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#virus</a>.<a href="https://scientificnetwork.de/tags/mosaic_virus" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#mosaic_virus</a> <a href="https://scientificnetwork.de/tags/agriculture" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#agriculture</a> <a href="https://scientificnetwork.de/tags/food_security" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#food_security</a> <a href="https://scientificnetwork.de/tags/aphids" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#aphids</a> <a href="https://scientificnetwork.de/tags/vectors" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#vectors</a> <a href="https://scientificnetwork.de/tags/siRNA" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#siRNA</a> <a href="https://scientificnetwork.de/tags/edsRNA" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#edsRNA</a> <a href="https://phys.org/news/2025-03-crops-rna-based-substances-avenue.html" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://phys.org/news/2025-03-crops-rna-based-substances-avenue.html</a>

Arli A PTulisan sains populer mengenai desain <a href="https://sciencemastodon.com/tags/siRNA" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#siRNA</a> untuk desain agen terapetik. Semoga bermanfaat! 🙏 <a href="https://generasipeneliti.id/tulisan.php?id=IDOk5y5bodI8ct&judul=Desain-in-silico-siRNA-dengan-Tools-Bioinformatika-untuk-keperluan-Terapetik" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://generasipeneliti.id/tulisan.php?id=IDOk5y5bodI8ct&judul=Desain-in-silico-siRNA-dengan-Tools-Bioinformatika-untuk-keperluan-Terapetik</a> <a href="https://sciencemastodon.com/tags/bioinformatika" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#bioinformatika</a> <a href="https://sciencemastodon.com/tags/biomedik" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#biomedik</a> <a href="https://sciencemastodon.com/tags/bioteknologi" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#bioteknologi</a>

Auscandoc“Our research shows that <a href="https://med-mastodon.com/tags/siRNA" class="mention hashtag" rel="tag">#siRNA</a> treatment can target the <a href="https://med-mastodon.com/tags/virus" class="mention hashtag" rel="tag">#virus</a> in key regions that do not change as the virus evolves, which means it works across all current <a href="https://med-mastodon.com/tags/variants" class="mention hashtag" rel="tag">#variants</a> of concern. Most importantly, we envisage that it will also work for existing and future <a href="https://med-mastodon.com/tags/SARS" class="mention hashtag" rel="tag">#SARS</a> <a href="https://med-mastodon.com/tags/coronaviruses" class="mention hashtag" rel="tag">#coronaviruses</a> that emerge,” “siRNA can stop <a href="https://med-mastodon.com/tags/SARSCoV2" class="mention hashtag" rel="tag">#SARSCoV2</a> replication by directly targeting the virus itself, which means there is no immune system involvement,” <a href="https://med-mastodon.com/@LordsofHardwired/110874679883984122" target="_blank" rel="nofollow noopener noreferrer" translate="no">https://med-mastodon.com/@LordsofHardwired/110874679883984122</a>

Nachiket VartakWe just put in a manuscript using <a href="https://mastodon.online/tags/siRNA" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#siRNA</a> for knockdown. Knockdown verified with RT-PCR and Western blot. Saw a phenotype. Rescued it with ectopic expression of the knocked down protein. A reviewer required us to repeat the experiments using <a href="https://mastodon.online/tags/CRISPR" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#CRISPR</a>, and why we didn''t use crispr in the first place ?<a href="https://mastodon.online/tags/thatsecondreviewer" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#thatsecondreviewer</a> <a href="https://mastodon.online/tags/academia" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#academia</a> <a href="https://mastodon.online/tags/cellbiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#cellbiology</a> A: Because we didn't need to, <expletive>.

Arli A PPaper from our team about <a href="https://sciencemastodon.com/tags/siRNA" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#siRNA</a> and <a href="https://sciencemastodon.com/tags/COVID19" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#COVID19</a>. Already published last year, but maybe still relevant 😌🙂. A Computational Design of siRNA in SARS-CoV-2 Spike Glycoprotein Gene and Its Binding Capability toward mRNA <a href="https://journal.ugm.ac.id/ijc/article/view/68415/0" rel="nofollow noopener noreferrer" target="_blank">https://journal.ugm.ac.id/ijc/article/view/68415/0</a>

Phys.orgReferenced link: <a href="https://medicalxpress.com/news/2023-05-scientists-sirna-therapy-lung.html" rel="nofollow noopener noreferrer" target="_blank">https://medicalxpress.com/news/2023-05-scientists-sirna-therapy-lung.html</a> Discuss on <a href="https://discu.eu/q/https://medicalxpress.com/news/2023-05-scientists-sirna-therapy-lung.html" rel="nofollow noopener noreferrer" target="_blank">https://discu.eu/q/https://medicalxpress.com/news/2023-05-scientists-sirna-therapy-lung.html</a>Originally posted by Phys.org / @physorg_com: <a href="http://nitter.platypush.tech/medical_xpress/status/1653481680504606759#m" rel="nofollow noopener noreferrer" target="_blank">http://nitter.platypush.tech/medical_xpress/status/1653481680504606759#m</a>RT by @physorg_com: Scientists deliver <a href="https://social.platypush.tech/tags/siRNA" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#siRNA</a> therapy to lung @PNASNews <a href="https://pnas.org/doi/10.1073/pnas.2219523120" rel="nofollow noopener noreferrer" target="_blank">https://pnas.org/doi/10.1073/pnas.2219523120</a> <a href="https://medicalxpress.com/news/2023-05-scientists-sirna-therapy-lung.html" rel="nofollow noopener noreferrer" target="_blank">https://medicalxpress.com/news/2023-05-scientists-sirna-therapy-lung.html</a>

Guillermo Peris :verified: 🧬💻Este meme sale en mi próximo artículo/charla sobre microARN. XDDD <a href="https://mstdn.social/tags/xp" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#xp</a> --- RT @DNA_RNA_Uni I laughed so hard 😆😅😚<a href="https://mstdn.social/tags/RNAi" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#RNAi</a> <a href="https://mstdn.social/tags/siRNA" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#siRNA</a> <a href="https://mstdn.social/tags/miRNA" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#miRNA</a> <a href="https://mstdn.social/tags/featuredpaper" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#featuredpaper</a> <a href="https://mdpi.com/1422-0067/23/23/14755" rel="nofollow noopener noreferrer" target="_blank">https://mdpi.com/1422-0067/23/23/14755</a> <a href="https://twitter.com/DNA_RNA_Uni/status/1597927406136086528" rel="nofollow noopener noreferrer" target="_blank">https://twitter.com/DNA_RNA_Uni/status/1597927406136086528</a>

Thiago CarvalhoAedes aegypti Dicer2 mutants "Our Dicer2 null mutant line is viable and fertile, and only displays minor fitness defects despite being unable to produce siRNAs. The loss of Dicer2 affects early viral replication and systemic viral dissemination of four medically significant arboviruses (chikungunya, Mayaro, dengue, and <a href="https://qoto.org/tags/zika" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#zika</a> viruses) representing two viral families. However, measures of virus transmission potential indicate that Dicer2 null mutants and wild-type mosquitoes display an overall similar level of vector competence. Additionally, Dicer2 null mutants undergo significant virus-induced mortality during infection with <a href="https://qoto.org/tags/chikungunya" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#chikungunya</a> virus, but not <a href="https://qoto.org/tags/dengue" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#dengue</a> virus." <a href="https://qoto.org/tags/siRNA" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#siRNA</a> <a href="https://qoto.org/tags/crispr" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#crispr</a> <a href="https://qoto.org/tags/preprint" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#preprint</a> <a href="https://www.biorxiv.org/content/10.1101/2022.11.14.516413v1" rel="nofollow noopener noreferrer" target="_blank">https://www.biorxiv.org/content/10.1101/2022.11.14.516413v1</a>

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