Unraveling the unraveller: novel protein-protein interactions and roles of regulatory protein HNRNPU.
#preLight prepared by Candy Rutihinda, R Bibata Ouédraogo and Bryce Rampal
#uMontreal
@umontreal.ca
Metastatic Matchmaking: CD24 Brings Tumour Cells and Platelets Together
Check out this excellent #preLight from Harvey Roweth, which includes answers and future directions from the authors of the preprint.
Using a forebrain assembloid model, Kim & team unveil that gene-regulating crosstalk between neurons & glial cells potentially contributes to developing schizophrenia. #preprint
#preLight prepared by Justine Gromaire, Aimee Xinxo & Jeremie Van Prooijen #uMontreal
Who “belongs” in biology?
The first comprehensive analysis of the LGBTQ+ climate in the biological sciences! #LGBTinSTEM #preprint 
#preLight prepared by Ryan, Stefan & Reinier
https://prelights.biologists.com/highlights/lgbtq-realities-in-the-biological-sciences/
Swirl, align, invade!
Collective motion of cancer cells radially aligns collagen fibers and promotes invasion. #preprint Aashrith Saraswathibhatla et al. #theChaudhurilab
Check out the latest #preLight from Sharvari Pitke
‘These cracks, they let the developing cells in: A chronicle of trabeculation in the developing zebrafish heart’ 
Theodora Stougiannou highlights recent work from Christopher Chan Jin Jie, Rashmi Priya & team. #preprint
Check out the #preLight
https://prelights.biologists.com/highlights/mechanical-fracturing-of-the-extracellular-matrix-patterns-the-vertebrate-heart/
A new study from Washington State University explores the transgenerational impact of prenatal cannabis exposure in mice. #preprint
#preLight prepared by Behiye Sanliturk, Ali Gharbienne & Solal Aubailly #uMontreal
We can make decisions in our sleep! This #preprint reveals how the different sleep stages alter the underlying mechanisms of decision-making.
#preLight prepared by Joseph Lefèvre López & Nghi Vuong Nguyen #uMontreal
First preLights post from Jenny Singh!
She covers work showing that Lamin A/C maintains replication fork integrity during mild replication stress by modulating chromatin structure and restraining RECQ1 activity. #preprint
#preLight
https://prelights.biologists.com/highlights/nucleoplasmic-lamin-a-c-controls-replication-fork-restart-upon-stress-by-modulating-local-h3k9me3-and-adp-ribosylation-levels/
So many features…so little time: bumblebees show optimization of cue integration in a memory task. 
Really entertaining #preLight prepared by Tim Schwanitz & Cemre Coskun in which they highlight recent work from Anna Stöckl & team
Why do preterm neonates struggle to control sepsis?
“This study provides insight into how Krüppel-like factor 2 (KLF2) is involved” and shows that “KLF2 is a promising target in successfully treating newborns with sepsis.”
#preLight from Sydney Call & Sahan Senanayaka #ImmunobiologyUA !
Not all aspartate limitation is created equal.
An aspartate biosensor reveals that inhibiting succinate dehydrogenase results in defects in pyrimidine synthesis and replication stress, unique from other methods of aspartate limitation.
First #preLight from Hannah Pletcher
https://prelights.biologists.com/highlights/succinate-dehydrogenase-loss-causes-cascading-metabolic-effects-that-impair-pyrimidine-biosynthesis/
Blurring the lines between retrotransposons & viruses!
sORF2 enables envelope-independent, direct cell-to-cell transmission of retrotransposons in Drosophila, challenging our understanding of mobile genetic elements.
#preLight from Ally Simpson & Alyss Humphrey #ImmunobiologyUA !
https://prelights.biologists.com/highlights/direct-cell-to-cell-transmission-of-retrotransposons/
Macrophages sense and adapt. Immuno-mechanics meets cancer research.
Roberto Amadio highlights recent work from Wenyan Xie and colleagues.
Roberto: “The huge amount of data (…) is of high value not only to cancer biologists, but also to cell biologists and clinicians”.
Seeing stars 
Astrocytes in primary visual cortex drive migraine pain.
Check out the new preLights post from Vanessa Ehlers highlighting a recent study from Dara Bree, Dan Levy & team. #preprint
#preLight https://prelights.biologists.com/highlights/cortical-astrocyte-activation-triggers-meningeal-nociception-and-migraine-like-pain/
Defence mechanism inception!
Listeria prophages protect their host bacteria with anti-phage systems, leaving them susceptible to their own defence systems - read how this may actually be an evolutionary advantage!
#preLight from Briana Guzman, Noah Franz #ImmunobiologyUA !
ISR alone won’t cut it: stalled ribosomes block stress granule formation despite ISR activation.
Mohammed Jalloh highlights a #preprint from the Moon lab.
#preLight https://prelights.biologists.com/highlights/trna-synthetase-activity-is-required-for-stress-granule-and-p-body-assembly/
Led by Samuel Campos, the IMB565 class #ImmunobiologyUA has preLighted recent #immunology preprints.
“Resident Killers: Tonsil resident NK cells show potential against early HIV-1 infection.” #preprint from David Perea, Maria Buzon & team
#preLight prepared by Sukirti Shivpuri, Jared Alvarez & Vanessa Brizuela
