Spotify for PodcastersNeurosalience #S4E9 with Marsel Mesulam - 50+ years of brain research and importance of bubbles by OHBM NeurosalienceIt is our great pleasure and deep honor to host Dr. Marsel Mesulam who
is a giant in the field of Neurology and one of founders of OHBM. Dr.
Mesulam is Chief of Behavioral Neurology and the Ruth Dunbar Davee
Professor of Neuroscience at Northwestern University Feinberg School of
Medicine, and Professor of Behavioral Neurology at the Weinberg College
of Arts and Sciences.Dr. Mesulam received his MD from Harvard
Medical School in 1972, and in 1976 completed residencies at Boston
City Hospital and Beth Israel Deaconess Medical Center in Boston. After a
1 year postdoc at Harvard University he began his tenure in Chicago at
Northwestern. Dr. Mesulam's work has been both prodigious and impactful
over the years, as his almost 1000 papers have been cited over 140
thousand times. He has written the seminal book, Principles of
Behavioral and Cognitive Neurology, and has produced many landmark
papers - a few of which we'll discuss in the podcast. One paper that we
consider a masterpiece was published in Brain in 1998 and titled From
Sensation to Cognition. This can be considered as a required reading for
everyone in the field of brain mapping as it lays out so concisely and
eloquently, a breathtaking perspective of the structure and functional
organization of the human brain.
Dr. Mesulam's research is extremely broad and diverse, having impacted
such areas as neural networks and functional imaging, Dementia,
Alzheimer's Disease, Primary Progressive Aphasia (PPA), Cholinergic
Pathways, Acetylcholinesterase Studies, Cognitive Psychology, Neurology,
and Neuropsychiatry. He also developed, early in his career, a neuronal
marker, Tetramethyl benzidine, that profoundly impacted research in
this area.
In this inspiring conversation, Peter and Marsel discuss his early
career and what was important for his success, delve into research
culture and the value of opportunistic research, and the value of having
the freedom and resources to try many things and rapidly change
directions that follow interesting leads. They also discuss some of the
exciting early days of Neuroimaging and OHBM. Lastly, we go into some of
his current research on Primary Progressive Aphasia (PPA) and the study
of temporal pole disease as a window to temporal pole functional
significance.
We hope that you enjoy this conversation.
Episode producers:Alfie WearnOmer Faruk Gulban