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#MultipleSclerosis

22 posts11 participants3 posts today
Gregory MS<p><a href="https://gregory-ms.com/articles/302249/?utm_source=fediverse&amp;utm_medium=mastodon&amp;utm_content=article_302249" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/302249</span><span class="invisible">/?utm_source=fediverse&amp;utm_medium=mastodon&amp;utm_content=article_302249</span></a></p><p>Myelination is essential for normal brain function. The mechanisms governing neuron-oligodendrocyte interactions that ensure proper myelination levels remain poorly understood. TFEB is a molecular link that connects extrinsic neuronal cues to intrinsic oligodendriacte transcriptional programs. Neurons sequester most of the T FEB protein in the cytoplasm of</p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
Gregory MS<p><a href="https://gregory-ms.com/articles/302254/?utm_source=fediverse&amp;utm_medium=mastodon&amp;utm_content=article_302254" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/302254</span><span class="invisible">/?utm_source=fediverse&amp;utm_medium=mastodon&amp;utm_content=article_302254</span></a></p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
Gregory MS<p><a href="https://gregory-ms.com/articles/302255/?utm_source=fediverse&amp;utm_medium=mastodon&amp;utm_content=article_302255" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/302255</span><span class="invisible">/?utm_source=fediverse&amp;utm_medium=mastodon&amp;utm_content=article_302255</span></a></p><p>Exendin-4 (Ex-4) is a glucagon-like peptide-1 receptor (GLP-1R) agonist that mitigates microglia-driven neuroinflammation after spinal cord injury (SCI). Ex-4 treatment significantly attenuated macrophage senescence, restored efferocytotic function, and reduced neuronal injury and astrocyte activation.</p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
Jonathan Kamens 86 47<p>Hey folks.<br>I rarely post <a href="https://federate.social/tags/MutualAid" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MutualAid</span></a> asks, but today is an exception.<br>My friend of many years, Aaron Askanase, has progressive <a href="https://federate.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> and needs a <a href="https://federate.social/tags/ServiceDog" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ServiceDog</span></a> to help him continue to live a dignified life.<br>Aaron and his family are truly good people, and this will make a huge difference in their lives.<br>Please donate, if you can. Every little bit helps. Thank you!<br>NOTE: Donations go through the org, not Aaron specifically, and are tax-deductible.<br><a href="https://giving.classy.org/campaign/706948/donate" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">giving.classy.org/campaign/706</span><span class="invisible">948/donate</span></a></p>
Gregory MS<p><a href="https://gregory-ms.com/articles/302223/?utm_source=fediverse&amp;utm_medium=mastodon&amp;utm_content=article_302223" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/302223</span><span class="invisible">/?utm_source=fediverse&amp;utm_medium=mastodon&amp;utm_content=article_302223</span></a></p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
Gregory MS<p><a href="https://gregory-ms.com/articles/302226/?utm_source=fediverse&amp;utm_medium=mastodon&amp;utm_content=article_302226" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/302226</span><span class="invisible">/?utm_source=fediverse&amp;utm_medium=mastodon&amp;utm_content=article_302226</span></a></p><p>Cocin improves axonal regrowth and ultrastructural remyelination in rat model of sciatic nerve crush injury. Crocin attenuated mitochondrial dysfunction by reducing mitochondrial ROS and restoring membrane potential.</p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
Gregory MS<p><a href="https://gregory-ms.com/articles/302166/?utm_source=fediverse&amp;utm_medium=mastodon&amp;utm_content=article_302166" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/302166</span><span class="invisible">/?utm_source=fediverse&amp;utm_medium=mastodon&amp;utm_content=article_302166</span></a></p><p>Toll-like receptor 9 (TLR9) is a deoxyribose nucleic acid (DNA) sensor. It plays a role in astrocyte activation and its contribution to multiple sclerosis (MS) pathogenesis. TLR9 and the cGAS-STING pathway are thought to be involved in MS. Treatment with unmethylated CpG oligodeoxynucleotides significantly reduced astro Cytosine-phosphoroth</p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
Gregory MS<p><a href="https://gregory-ms.com/articles/302195/?utm_source=fediverse&amp;utm_medium=mastodon&amp;utm_content=article_302195" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/302195</span><span class="invisible">/?utm_source=fediverse&amp;utm_medium=mastodon&amp;utm_content=article_302195</span></a></p><p>Buyang Huanwu Decoction (BYHWD) is used in traditional Chinese medicine to treat post-stroke sequelae. The study aimed to determine if BYHWD facilitates post-ischemic white matter restoration via TREM2-dependent mechanisms. It markedly improved long-term neurological outcomes and mitigated white matter injury in tMCAO mice.</p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
Gregory MS<p><a href="https://gregory-ms.com/articles/302126/?utm_source=fediverse&amp;utm_medium=mastodon&amp;utm_content=article_302126" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/302126</span><span class="invisible">/?utm_source=fediverse&amp;utm_medium=mastodon&amp;utm_content=article_302126</span></a></p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
Gregory MS<p><a href="https://gregory-ms.com/articles/302143/?utm_source=fediverse&amp;utm_medium=mastodon&amp;utm_content=article_302143" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/302143</span><span class="invisible">/?utm_source=fediverse&amp;utm_medium=mastodon&amp;utm_content=article_302143</span></a></p><p>Multiple sclerosis (MS) is characterized by immune-mediated injury to myelin and oligodendrocytes (OLs). Repair depends on the ability of OL lineage cells to form new myelin and ensheathe axons. The majority of pathways and genes related to myelination and immune interactions were downregulated in adult cell samples compared to pediatric samples.</p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
Gregory MS<p><a href="https://gregory-ms.com/articles/302056/?utm_source=fediverse&amp;utm_medium=mastodon&amp;utm_content=article_302056" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/302056</span><span class="invisible">/?utm_source=fediverse&amp;utm_medium=mastodon&amp;utm_content=article_302056</span></a></p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
Megan Lynch (she/her)<p>"We talked all about the causes or MS, the neurobiology, the early symptoms, treatments, the interventions that can slow down progression, new therapies that are on the horizon, the oftentimes agonizing journey to a diagnosis, and advice for those who've had MS for a while — or are newly in the community. Also yeah: weed."</p><p><a href="https://www.alieward.com/ologies/neuropathoimmunology" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">alieward.com/ologies/neuropath</span><span class="invisible">oimmunology</span></a> <span class="h-card" translate="no"><a href="https://a.gup.pe/u/disability" class="u-url mention" rel="nofollow noopener" target="_blank">@<span>disability</span></a></span> <a href="https://ecoevo.social/tags/Disability" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Disability</span></a> <a href="https://ecoevo.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a></p>
Gregory MS<p><a href="https://gregory-ms.com/articles/301957/?utm_source=fediverse&amp;utm_medium=mastodon&amp;utm_content=article_301957" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/301957</span><span class="invisible">/?utm_source=fediverse&amp;utm_medium=mastodon&amp;utm_content=article_301957</span></a></p><p>Tumor surgery or trauma in the maxillofacial region may cause injuries to facial nerves. The gold standard of treatment for peripheral nerve injury is autologous nerve grafting. New 3D structures fabricated only from cells by using Bio 3D printers are attracting attention. Dental pulp stem cells (DPSCs) are a promising cell source because of their high clonogenic, proliferative, and multidiffer...</p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
Gregory MS<p><a href="https://gregory-ms.com/articles/301984/?utm_source=fediverse&amp;utm_medium=mastodon&amp;utm_content=article_301984" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/301984</span><span class="invisible">/?utm_source=fediverse&amp;utm_medium=mastodon&amp;utm_content=article_301984</span></a></p><p>Neuroinflammation is a key defense mechanism against brain infections and injury. Ardisia elliptica Thunb (Primulaceae) has been used to treat diarrhea with fever in Thai traditional medicine, but the potential of A. elliptica fruit to modulate neuroinflammation remains unexplored. Lipopolysaccharide (LPS) was used to activate BV2 microglia and RAW264.7 macrophages. The 90% ethanol extract of A</p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
Gregory MS<p><a href="https://gregory-ms.com/articles/301993/?utm_source=fediverse&amp;utm_medium=mastodon&amp;utm_content=article_301993" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/301993</span><span class="invisible">/?utm_source=fediverse&amp;utm_medium=mastodon&amp;utm_content=article_301993</span></a></p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
Gregory MS<p><a href="https://gregory-ms.com/articles/301995/?utm_source=fediverse&amp;utm_medium=mastodon&amp;utm_content=article_301995" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/301995</span><span class="invisible">/?utm_source=fediverse&amp;utm_medium=mastodon&amp;utm_content=article_301995</span></a></p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
dave@yourcomputer​ $:cursor:<p>don’t mind me, just call me Dave “no new lesions since the last scan” Williams</p><p>This is after +2 lesions in the last interval.</p><p><a href="https://basilisk.gallery/tags/multiplesclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>multiplesclerosis</span></a></p>
Gregory MS<p><a href="https://gregory-ms.com/articles/301901/?utm_source=fediverse&amp;utm_medium=mastodon&amp;utm_content=article_301901" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/301901</span><span class="invisible">/?utm_source=fediverse&amp;utm_medium=mastodon&amp;utm_content=article_301901</span></a></p><p>Neurodegenerative conditions (NDs) are major causes of disability and mortality worldwide. Currently, there is no definitive cure for NDs. Mesenchymal stem cells (MSCs) have gained attention in regenerative medicine. Extracellular vesicles (EVs) derived from MSCs have shown great promise as a cell-free therapeutic approach. Preconditioning strategies, including hypoxia, 3D cultures, and biochem...</p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
Gregory MS<p><a href="https://gregory-ms.com/articles/301868/?utm_source=fediverse&amp;utm_medium=mastodon&amp;utm_content=article_301868" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">gregory-ms.com/articles/301868</span><span class="invisible">/?utm_source=fediverse&amp;utm_medium=mastodon&amp;utm_content=article_301868</span></a></p><p><a href="https://mastodon.social/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> <a href="https://mastodon.social/tags/MSchat" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MSchat</span></a> <a href="https://mastodon.social/tags/MS" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MS</span></a> <a href="https://mastodon.social/tags/Neurology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neurology</span></a></p>
swisslet<p>That sounds a bit conceited. It really isn’t meant to. I’ve never been a particularly talented runner. I only started running marathons about 6 years after my <a href="https://mas.to/tags/MultipleSclerosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MultipleSclerosis</span></a> diagnosis and was mainly powered by sheer bloody-mindedness. I want everyone, whatever speed they run, to feel the simple joy and achievement of participation. Too much coaching doesn’t celebrate the runners at the back.</p>
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