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#mechanobiology

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preLights

New #preLights post from Vibha Singh! 👀

In this highlighted #preprint, the research team (#NalbantLab) introduces a powerful new approach to studying mechanobiological regulation in cancer. In doing so, they describe how tumour cells manage to “pull” themselves away from the tumour bulk during invasion.

Read the #preLight here 👉 prelights.biologists.com/highl

#CancerResearch#Optogenetics#Mechanobiology
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MPI for the Science of Light

Exploring the Frontiers of #Mechanobiology

Mechanobiology Conference III ›From Fundamental Research to Applications‹, organized by Prof. Benoît Ladoux, Head of Division ›Tissue Mechanobiology‹ at #MPZPM, takes place July 6–12, 2025 at ICISE in Quy Nhon, Vietnam. Topics include cell signaling, disease development, biomaterials, theoretical biophysics & more.

📅 Deadlines: Abstracts – Apr 30 | Registration – Jun 6

More information here 👉 icisequynhon.com/conferences/2

The picture shows the official flyer with more information about the conference, for example the scientific organizing committee and the invited speakers.
Public
preLights

Hearts in time ❤️

The first #preLight of Theodora Stougiannou covers work (from Boris Martinac & team) showing that deletion of the Piezo1 gene in mice results in reduced survival, premature cardiac ageing and fibrosis. #preprint

Take a look! ⬇️ 👀 prelights.biologists.com/highl

preLightsDeletion of PIEZO1 in adult cardiomyocytes accelerates cardiac aging and causes premature death - preLightsPIEZO1 is a channel protein sensitive to mechanical deformation, expressed in many different cell types (including cardiomyocytes). Deletion of the Piezo1 gene in mice results, among others, in reduced survival, premature cardiac aging and fibrosis.
#ageing#biology#cardiology
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Jocelyn Etienne – research

#Cells can surf, we maintain, with a revised version of our paper on #arXiv now !

What they need to be is nothing more than the schematic below – a treadmilling bar in frictional contact with a soft elastic substrate. If soft enough, #symmetry breaking occurs because of the #nonlocal #feedback of these friction forces via the substrate and the cell starts to move.

#mechanobiology of #cellmigration
arxiv.org/abs/2303.09666

Sketch of the cell part of the model. Add that the substrate is elastic and there's friction with it and you're done with the hypotheses.
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