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#granuloma

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Gabriele Pollara<p>Interesting study showing balance between bacterial &amp; host factors determining granuloma formation and control of infection. This example being <a href="https://med-mastodon.com/tags/Yersinia" class="mention hashtag" rel="tag">#<span>Yersinia</span></a>. <br /><a href="https://med-mastodon.com/tags/granuloma" class="mention hashtag" rel="tag">#<span>granuloma</span></a> <a href="https://med-mastodon.com/tags/immunology" class="mention hashtag" rel="tag">#<span>immunology</span></a> <a href="https://med-mastodon.com/tags/academia" class="mention hashtag" rel="tag">#<span>academia</span></a> <a href="https://med-mastodon.com/tags/Science" class="mention hashtag" rel="tag">#<span>Science</span></a> <a href="https://med-mastodon.com/tags/ScienceMastodon" class="mention hashtag" rel="tag">#<span>ScienceMastodon</span></a> </p><p>Inflammatory monocytes promote granuloma control of Yersinia infection | Nature Microbiology</p><p><a href="https://www.nature.com/articles/s41564-023-01338-6?utm_source=nmicrobiol_etoc&amp;utm_medium=email&amp;utm_campaign=toc_41564_8_4&amp;utm_content=20230404" target="_blank" rel="nofollow noopener noreferrer" translate="no"><span class="invisible">https://www.</span><span class="ellipsis">nature.com/articles/s41564-023</span><span class="invisible">-01338-6?utm_source=nmicrobiol_etoc&amp;utm_medium=email&amp;utm_campaign=toc_41564_8_4&amp;utm_content=20230404</span></a></p>
Gabriele Pollara<p>Fabulous resource for gaining detailed cellular &amp; spatial understanding of immunobiology at the site of human granulomas. <a href="https://med-mastodon.com/tags/sarcoid" class="mention hashtag" rel="tag">#<span>sarcoid</span></a> <a href="https://med-mastodon.com/tags/TB" class="mention hashtag" rel="tag">#<span>TB</span></a> <a href="https://med-mastodon.com/tags/tuberculosis" class="mention hashtag" rel="tag">#<span>tuberculosis</span></a> <a href="https://med-mastodon.com/tags/tuberculosis" class="mention hashtag" rel="tag">#<span>tuberculosis</span></a> <a href="https://med-mastodon.com/tags/leprosy" class="mention hashtag" rel="tag">#<span>leprosy</span></a> <a href="https://med-mastodon.com/tags/granuloma" class="mention hashtag" rel="tag">#<span>granuloma</span></a> <a href="https://med-mastodon.com/tags/immunology" class="mention hashtag" rel="tag">#<span>immunology</span></a> <a href="https://med-mastodon.com/tags/singlecell" class="mention hashtag" rel="tag">#<span>singlecell</span></a> <a href="https://med-mastodon.com/tags/academia" class="mention hashtag" rel="tag">#<span>academia</span></a> <a href="https://med-mastodon.com/tags/science" class="mention hashtag" rel="tag">#<span>science</span></a> <br /><span class="h-card" translate="no"><a href="https://mstdn.science/@ImmunityCP" class="u-url mention">@<span>ImmunityCP</span></a></span> <br /><a href="https://www.cell.com/immunity/fulltext/S1074-7613(23)00024-9?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1074761323000249%3Fshowall%3Dtrue" target="_blank" rel="nofollow noopener noreferrer" translate="no"><span class="invisible">https://www.</span><span class="ellipsis">cell.com/immunity/fulltext/S10</span><span class="invisible">74-7613(23)00024-9?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1074761323000249%3Fshowall%3Dtrue</span></a></p>
Gabriele Pollara<p>Such a neat story about bacterial virulence factor (EsxM) contributing to bone dissemination of TB disease through actions on macrophage motility. <span class="h-card" translate="no"><a href="https://mstdn.science/@cellpress" class="u-url mention">@<span>cellpress</span></a></span> </p><p>Unlikely to be the whole story, and it&#39;s taking a leap from zebrafish model to extrapolate human TB disease phenotype, but v plausible that bacterial manipulation of host immunobiology can alter natural history of <a href="https://med-mastodon.com/tags/TB" class="mention hashtag" rel="tag">#<span>TB</span></a> disease. <a href="https://med-mastodon.com/tags/immunology" class="mention hashtag" rel="tag">#<span>immunology</span></a> <a href="https://med-mastodon.com/tags/macrophages" class="mention hashtag" rel="tag">#<span>macrophages</span></a> <a href="https://med-mastodon.com/tags/granuloma" class="mention hashtag" rel="tag">#<span>granuloma</span></a> <a href="https://med-mastodon.com/tags/bone" class="mention hashtag" rel="tag">#<span>bone</span></a> </p><p><a href="https://www.cell.com/cell/fulltext/S0092-8674(22)01361-7?dgcid=raven_jbs_etoc_email" target="_blank" rel="nofollow noopener noreferrer" translate="no"><span class="invisible">https://www.</span><span class="ellipsis">cell.com/cell/fulltext/S0092-8</span><span class="invisible">674(22)01361-7?dgcid=raven_jbs_etoc_email</span></a></p>