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datum (n=1)"SARS-CoV-2 spike RNA- and SARS-CoV-2-related inflammation persist in the epipharynx for more than six months post infection. Although no expression of the SARS-CoV-2 spike protein in the epipharynx was evident in these patients with long COVID, genetic analysis revealed activation of [...] the SARS-CoV-2 signalling pathway in epithelial cells, B cells, and pDCs. This aligns with theories that even nonactive viral fragments may possess biological significance. This persistence of inflammation, identified for the first time at the genetic level, highlights the epipharynx as a critical site for continual immune responses in long COVID patients, suggesting that residual viral antigens may contribute to the chronic symptoms experienced""After the administration of EAT [epipharyngeal abrasive therapy] once a week for 3 months, the expression of viral RNA disappeared in patients 1 and 2. Patient 3 presented a substantial reduction in viral RNA expression; although complete clearance was not achieved, a marked decrease was observed.""observed dysregulation of immune and ciliary pathways" - might explain the chronic nonsmoker cough that seems more common now"These findings suggest that T cells still play a subtle role in the immune dysregulation observed in patients with long COVID. Collectively, these findings indicate that interactions among pDCs, B cells, plasma cells, and T cells contribute to the chronic inflammation and immune dysregulation characteristic of patients with long COVID""In the pre-EAT state of long COVID Patient 2, the tissue surface was predominantly covered by ciliated epithelium (Cluster 7). In contrast, following treatment, the ciliated epithelium was no longer observed, and a new cluster of squamous epithelial cells (Cluster 12) emerged""EAT effectively eliminates the inflamed ciliated epithelium in patients with long COVID and induces the formation of squamous cells with high barrier function"<a href="https://www.nature.com/articles/s41598-025-92908-7" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.nature.com/articles/s41598-025-92908-7</a>thanks <a href="https://mastodon.social/@MEActNOW" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@MEActNOW</a> <a href="https://zeroes.ca/tags/COVID" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#COVID</a> <a href="https://zeroes.ca/tags/COVID19" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#COVID19</a> <a href="https://zeroes.ca/tags/SARSCoV2" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#SARSCoV2</a> <a href="https://zeroes.ca/tags/epithelium" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#epithelium</a> <a href="https://zeroes.ca/tags/CovidIsNotOver" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#CovidIsNotOver</a> <a href="https://zeroes.ca/tags/CovidCompetent" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#CovidCompetent</a> <a href="https://zeroes.ca/tags/CovidConscious" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#CovidConscious</a> <a href="https://zeroes.ca/tags/AirborneAware" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#AirborneAware</a> <a href="https://zeroes.ca/tags/health" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#health</a>

Giuseppe MichieliVariable <a href="https://mstdn.science/tags/DPP4" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#DPP4</a> <a href="https://mstdn.science/tags/expression" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#expression</a> in multiciliated cells of the <a href="https://mstdn.science/tags/human" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#human</a> <a href="https://mstdn.science/tags/nasal" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#nasal</a> <a href="https://mstdn.science/tags/epithelium" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#epithelium</a> as a determinant for <a href="https://mstdn.science/tags/MERS" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#MERS</a>-CoV tropism, <a href="https://etidiohnew.blogspot.com/2025/03/variable-dpp4-expression-in.html" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://etidiohnew.blogspot.com/2025/03/variable-dpp4-expression-in.html</a>

Giuseppe MichieliA 2022 avian <a href="https://mstdn.science/tags/H5N1" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H5N1</a> <a href="https://mstdn.science/tags/influenza" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#influenza</a> A virus from clade 2.3.4.4b attaches to and replicates better in <a href="https://mstdn.science/tags/human" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#human</a> respiratory <a href="https://mstdn.science/tags/epithelium" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#epithelium</a> than a 2005 H5N1 virus from clade 2.3.2.1Source: BioRxIV, AbstractBackground: Highly pathogenic avian influenza (HPAI) H5 viruses of the A/Goose/Guangdong/1/1996 (GsGd) lineage pose significant global risks to wildlife, domestic animals, and humans. Recent cross-species transmission events to mammals, including humans, highlight this risk.…<a href="https://etidioh.wordpress.com/2024/11/28/a-2022-avian-h5n1-influenza-a-virus-from-clade-2-3-4-4b-attaches-to-and-replicates-better-in-human-respiratory-epithelium-than-a-2005-h5n1-virus-from-clade-2-3-2-1/" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://etidioh.wordpress.com/2024/11/28/a-2022-avian-h5n1-influenza-a-virus-from-clade-2-3-4-4b-attaches-to-and-replicates-better-in-human-respiratory-epithelium-than-a-2005-h5n1-virus-from-clade-2-3-2-1/</a>

CellBioNewsStudy pinpoints <a href="https://scientificnetwork.de/tags/cellular" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#cellular</a> response to <a href="https://scientificnetwork.de/tags/pressure" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#pressure</a> in <a href="https://scientificnetwork.de/tags/sea_star" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#sea_star</a> <a href="https://scientificnetwork.de/tags/embryos" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#embryos</a>.<a href="https://scientificnetwork.de/tags/Patiria" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Patiria</a> <a href="https://scientificnetwork.de/tags/epithelium" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#epithelium</a><a href="https://phys.org/news/2024-05-cellular-response-pressure-sea-star.html" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://phys.org/news/2024-05-cellular-response-pressure-sea-star.html</a>

Matt WillemsenA Skin-Deep Wound Can Trigger Gut Bacteria Changes <a href="https://www.sciencealert.com/a-skin-deep-wound-can-trigger-gut-bacteria-changes" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.sciencealert.com/a-skin-deep-wound-can-trigger-gut-bacteria-changes</a> <a href="https://mastodon.social/tags/health" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#health</a> <a href="https://mastodon.social/tags/dermatology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#dermatology</a> <a href="https://mastodon.social/tags/skin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#skin</a> <a href="https://mastodon.social/tags/gut" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#gut</a> <a href="https://mastodon.social/tags/bacteria" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#bacteria</a> <a href="https://mastodon.social/tags/epithelium" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#epithelium</a> <a href="https://mastodon.social/tags/inflammation" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#inflammation</a>

Jocelyn Etienne<a href="https://biologists.social/@preLights" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@preLights</a> And we also had a variant of your pathway C of <a href="https://scicomm.xyz/tags/epithelial" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#epithelial</a> fold formation : folding by *tensile* mechanical <a href="https://scicomm.xyz/tags/buckling" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#buckling</a>(Note: these are my hands on the photo, so technically this is my own's only and single published experiment!)<a href="https://scicomm.xyz/tags/epithelium" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#epithelium</a>

preLightsA different origami-guide: Irreversible folds in morphogenesis 🔰Teodora Piskova <a href="https://biologists.social/tags/RWTH" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#RWTH</a> covers work from the <a href="https://biologists.social/tags/MechgenLab" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#MechgenLab</a>“…this <a href="https://biologists.social/tags/preprint" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#preprint</a> seeks to explain how certain material behaviors of tissues matter for fundamental processes such as <a href="https://biologists.social/tags/morphogenesis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#morphogenesis</a>…”<a href="https://biologists.social/tags/preLight" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#preLight</a> 👉 <a href="https://prelights.biologists.com/highlights/elasto-plastic-transition-in-epithelial-folding-v2/" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://prelights.biologists.com/highlights/elasto-plastic-transition-in-epithelial-folding-v2/</a><a href="https://biologists.social/tags/biomechanics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#biomechanics</a> <a href="https://biologists.social/tags/development" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#development</a> <a href="https://biologists.social/tags/epithelium" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#epithelium</a> <a href="https://biologists.social/tags/mechanobiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#mechanobiology</a> <a href="https://biologists.social/tags/mechanosensing" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#mechanosensing</a>

CellBioNews<a href="https://scientificnetwork.de/tags/Cells" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Cells</a> in confinement and people in crowds have similar behaviors, shows study.<a href="https://scientificnetwork.de/tags/biophysics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#biophysics</a> <a href="https://scientificnetwork.de/tags/bioengineering" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#bioengineering</a> <a href="https://scientificnetwork.de/tags/epithelium" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#epithelium</a><a href="https://phys.org/news/2023-07-cells-confinement-people-crowds-similar.html" rel="nofollow noopener noreferrer" target="_blank">https://phys.org/news/2023-07-cells-confinement-people-crowds-similar.html</a>

Jocelyn Etienne"Overall, our data suggest that the orientation of spindles in the epithelium plane requires a threshold level of mechanical tension at intercellular junctions." Also at <a href="https://www.biorxiv.org/content/10.1101/2022.01.30.478396v1" rel="nofollow noopener noreferrer" target="_blank">https://www.biorxiv.org/content/10.1101/2022.01.30.478396v1</a> without a paywall. <a href="https://scicomm.xyz/tags/epithelium" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#epithelium</a> <a href="https://scicomm.xyz/tags/mechanics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#mechanics</a>

Scientific FrontlineRinse aids in <a href="https://mastodon.social/tags/commercial" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#commercial</a> <a href="https://mastodon.social/tags/dishwashers" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#dishwashers</a> often contain <a href="https://mastodon.social/tags/alcohol" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#alcohol</a> <a href="https://mastodon.social/tags/ethoxylate" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ethoxylate</a>. This substance damages the <a href="https://mastodon.social/tags/intestinal" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#intestinal</a> <a href="https://mastodon.social/tags/epithelium" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#epithelium</a>, which can lead to chronic <a href="https://mastodon.social/tags/diseases" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#diseases</a>. <a href="https://mastodon.social/tags/Medical" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Medical</a> <a href="https://mastodon.social/tags/Microbiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Microbiology</a> <a href="https://mastodon.social/tags/sflorg" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#sflorg</a> <a href="https://www.sflorg.com/2022/12/med12012201.html" rel="nofollow noopener noreferrer" target="_blank">https://www.sflorg.com/2022/12/med12012201.html</a>

Christian TidonaDid you know that starting a high-fat <a href="https://mstdn.science/tags/diet" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#diet</a> causes an adaptation of the <a href="https://mstdn.science/tags/intestinal" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#intestinal</a> <a href="https://mstdn.science/tags/epithelium" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#epithelium</a> within only 24 hours?In this interesting study, Jacob Enriquez and colleagues at Cincinnati Children's Hospital Medical Center used physiological metrics and single-cell transcriptomics to interrogate the intestinal epithelial cell response to a high-fat diet in mice.Article in Cell Reports: <a href="https://www.cell.com/cell-reports/fulltext/S2211-1247(22)01512-1" rel="nofollow noopener noreferrer" target="_blank">https://www.cell.com/cell-reports/fulltext/S2211-1247(22)01512-1</a><a href="https://mstdn.science/tags/highfatdiet" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#highfatdiet</a> <a href="https://mstdn.science/tags/lipidmetabolism" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#lipidmetabolism</a> <a href="https://mstdn.science/tags/nutrition" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#nutrition</a> <a href="https://mstdn.science/tags/differentiation" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#differentiation</a> <a href="https://mstdn.science/tags/epigenetics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#epigenetics</a>

Ross A. Dunne :fosstodon:<a href="https://mstdn.social/@RouxJ" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@RouxJ</a> Hi, few comments: I think this is a terrible picture choice to represent <a href="https://fosstodon.org/tags/Alzheimer" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Alzheimer</a>'s, furthering unhelpful stereotypes, and 2) you don't link to the <a href="https://fosstodon.org/tags/study" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#study</a> here <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8854390/" rel="nofollow noopener noreferrer" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8854390/</a> which was 3) in *mice* not humans, using chemical damage to <a href="https://fosstodon.org/tags/nasal" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#nasal</a> <a href="https://fosstodon.org/tags/epithelium" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#epithelium</a> and 4) doesn't say anything about nosepicking, and 5) the study didn't find any increase in <a href="https://fosstodon.org/tags/AD" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#AD</a> <a href="https://fosstodon.org/tags/pathology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#pathology</a>: "we could not detect C. pneumoniae inclusions in the brain [...] did not detect any evidence of distinct Aβ deposits"

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