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Andrew Plested<a href="https://mas.to/@christlet" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@christlet</a> Christoph also gave a wonderful talk about his recent exciting work on "clearings" in the submembrane mesh of neurons.<a href="https://www.science.org/doi/full/10.1126/science.ado2032" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.science.org/doi/full/10.1126/science.ado2032</a><a href="https://mstdn.science/tags/Neuroscience" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Neuroscience</a> <a href="https://mstdn.science/tags/Endocytosis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Endocytosis</a> <a href="https://mstdn.science/tags/CellBiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#CellBiology</a> <a href="https://mstdn.science/tags/Biophysics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Biophysics</a>

PLOS BiologyFor <a href="https://fediscience.org/tags/epithelial" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#epithelial</a> tissue homeostasis, cell elimination & proliferation must balance. @DaikiUmetsu &co show that faster cell removal is associated with switch from isolated to clustered <a href="https://fediscience.org/tags/apoptosis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#apoptosis</a>, induced by ⬇️ <a href="https://fediscience.org/tags/endocytosis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#endocytosis</a> & EGFR signaling <a href="https://fediscience.org/tags/PLOSBiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#PLOSBiology</a> <a href="https://plos.io/403rQ3Y" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://plos.io/403rQ3Y</a>

PLOS Biology<a href="https://fediscience.org/tags/Clathrin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Clathrin</a>-mediated <a href="https://fediscience.org/tags/endocytosis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#endocytosis</a> (CME) is one of the main cellular trafficking processes, but how are CME sites initiated? @DavidGDrubin &co show that <a href="https://fediscience.org/tags/yeast" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#yeast</a> CALM/AP180 & FCHo1/2 adaptor proteins interact with Eps15 to promote CME initiation <a href="https://fediscience.org/tags/PLOSBiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#PLOSBiology</a> <a href="https://plos.io/4eCYlKA" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://plos.io/4eCYlKA</a>

CellBioNewsResearchers unveil <a href="https://scientificnetwork.de/tags/PI3K" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#PI3K</a> <a href="https://scientificnetwork.de/tags/enzyme" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#enzyme</a>'s dual accelerator and brake mechanisms.<a href="https://scientificnetwork.de/tags/cell_migration" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#cell_migration</a> <a href="https://scientificnetwork.de/tags/signalling" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#signalling</a> <a href="https://scientificnetwork.de/tags/endocytosis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#endocytosis</a> <a href="https://scientificnetwork.de/tags/p85%CE%B2" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#p85β</a> <a href="https://scientificnetwork.de/tags/AP2" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#AP2</a><a href="https://phys.org/news/2024-04-unveil-pi3k-enzyme-dual-mechanisms.html" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://phys.org/news/2024-04-unveil-pi3k-enzyme-dual-mechanisms.html</a>

jobRxivPostdoctoral Positions in Plant Proteostasis RWTH Aachen UniversityCome and join us! Great opportunity for <a href="https://mas.to/tags/postdoc" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#postdoc</a> or <a href="https://mas.to/tags/phd" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#phd</a> in @TrujilloLab @RWTH to work in targeted protein degradation <a href="https://mas.to/tags/TPD" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#TPD</a> <a href="https://mas.to/tags/endocytosis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#endocytosis</a> <a href="https://mas.to/tags/ubiquitin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ubiquitin</a>See the full job description on jobRxiv: <a href="https://jobrxiv.org/job/rwth-aachen-university-27778-postdoctoral-positions-in-plant-proteostasis-2/?feed_id=72561" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://jobrxiv.org/job/rwth-aachen-university-27778-postdoctoral-positions-in-plant-proteostasis-2/?feed_id=72561</a><a href="https://mas.to/tags/end" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#end</a>... <a href="https://jobrxiv.org/job/rwth-aachen-university-27778-postdoctoral-positions-in-plant-proteostasis-2/?feed_id=72561" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://jobrxiv.org/job/rwth-aachen-university-27778-postdoctoral-positions-in-plant-proteostasis-2/?feed_id=72561</a>

jobRxivPostdoctoral Positions in Plant Proteostasis RWTH Aachen UniversityCome and join us! Great opportunity for <a href="https://mas.to/tags/postdoc" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#postdoc</a> or <a href="https://mas.to/tags/phd" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#phd</a> in @TrujilloLab @RWTH to work in targeted protein degradation <a href="https://mas.to/tags/TPD" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#TPD</a> <a href="https://mas.to/tags/endocytosis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#endocytosis</a> <a href="https://mas.to/tags/ubiquitin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ubiquitin</a>See the full job description on jobRxiv: <a href="https://jobrxiv.org/job/rwth-aachen-university-27778-postdoctoral-positions-in-plant-proteostasis-2/?feed_id=71644" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://jobrxiv.org/job/rwth-aachen-university-27778-postdoctoral-positions-in-plant-proteostasis-2/?feed_id=71644</a><a href="https://mas.to/tags/end" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#end</a>... <a href="https://jobrxiv.org/job/rwth-aachen-university-27778-postdoctoral-positions-in-plant-proteostasis-2/?feed_id=71644" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://jobrxiv.org/job/rwth-aachen-university-27778-postdoctoral-positions-in-plant-proteostasis-2/?feed_id=71644</a>

CellBioNewsUncovering novel mechanisms of <a href="https://scientificnetwork.de/tags/endocytosis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#endocytosis</a> and <a href="https://scientificnetwork.de/tags/intracellular" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#intracellular</a> <a href="https://scientificnetwork.de/tags/trafficking" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#trafficking</a>.<a href="https://scientificnetwork.de/tags/TGN" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#TGN</a> <a href="https://scientificnetwork.de/tags/golgi" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#golgi</a> <a href="https://phys.org/news/2023-09-uncovering-mechanisms-endocytosis-intracellular-trafficking.html" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://phys.org/news/2023-09-uncovering-mechanisms-endocytosis-intracellular-trafficking.html</a>

Amelia GlazierHi <a href="https://biologists.social/tags/ScienceMastodon" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ScienceMastodon</a>, I'm happy to share with you the last Research Highlight from JCS Issue 15. Paul Gleeson and colleagues from the University of Melbourne and Rheinische Friedrich-Wilhelms-Universität Bonn use blood outgrowth endothelial cells to map out the intracellular trafficking route of human serum albumin. <a href="https://biologists.social/tags/CellBiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#CellBiology</a> <a href="https://biologists.social/tags/vascularbiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#vascularbiology</a> <a href="https://biologists.social/tags/endocytosis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#endocytosis</a> A rapid recycling route rescues HSA from degradation<a href="https://journals.biologists.com/jcs/article/136/15/e136_e1504/325864/A-rapid-recycling-route-rescues-HSA-from" rel="nofollow noopener noreferrer" target="_blank">https://journals.biologists.com/jcs/article/136/15/e136_e1504/325864/A-rapid-recycling-route-rescues-HSA-from</a>

jobRxivPostdoctoral Positions in Plant Proteostasis RWTH Aachen UniversityPostdoctoral Positions in Plant Proteostasis to study <a href="https://mas.to/tags/ubiquitinsignalling" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ubiquitinsignalling</a> <a href="https://mas.to/tags/endocytosis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#endocytosis</a> <a href="https://mas.to/tags/targetedproteindegradation" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#targetedproteindegradation</a> at the @RWTH in the @TrujilloLabSee the full job description on jobRxiv: <a href="https://jobrxiv.org/job/rwth-aachen-university-27778-postdoctoral-positions-in-plant-proteostasis/?feed_id=52035" rel="nofollow noopener noreferrer" target="_blank">https://jobrxiv.org/job/rwth-aachen-university-27778-postdoctoral-positions-in-plant-proteostasis/?feed_id=52035</a><a href="https://mas.to/tags/Science" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Science</a>... <a href="https://jobrxiv.org/job/rwth-aachen-university-27778-postdoctoral-positions-in-plant-proteostasis/?feed_id=52035" rel="nofollow noopener noreferrer" target="_blank">https://jobrxiv.org/job/rwth-aachen-university-27778-postdoctoral-positions-in-plant-proteostasis/?feed_id=52035</a>

jobRxivPostdoctoral Positions in Plant Proteostasis RWTH Aachen UniversityPostdoctoral Positions in Plant Proteostasis to study <a href="https://mas.to/tags/ubiquitinsignalling" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ubiquitinsignalling</a> <a href="https://mas.to/tags/endocytosis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#endocytosis</a> <a href="https://mas.to/tags/targetedproteindegradation" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#targetedproteindegradation</a> at the @RWTH in the @TrujilloLabSee the full job description on jobRxiv: <a href="https://jobrxiv.org/job/rwth-aachen-university-27778-postdoctoral-positions-in-plant-proteostasis/?feed_id=50851" rel="nofollow noopener noreferrer" target="_blank">https://jobrxiv.org/job/rwth-aachen-university-27778-postdoctoral-positions-in-plant-proteostasis/?feed_id=50851</a><a href="https://mas.to/tags/Science" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Science</a>... <a href="https://jobrxiv.org/job/rwth-aachen-university-27778-postdoctoral-positions-in-plant-proteostasis/?feed_id=50851" rel="nofollow noopener noreferrer" target="_blank">https://jobrxiv.org/job/rwth-aachen-university-27778-postdoctoral-positions-in-plant-proteostasis/?feed_id=50851</a>

Stephen RoyleThis new paper from Obashi and colleagues in the Taraska lab is very nice. It uses a FRET-CLEM approach to look at protein conformations in cells and tie those to ultrastructural correlates. Here they are looking at clathrin light chain dynamics relative to the clathrin cage during <a href="https://mastodon.social/tags/endocytosis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#endocytosis</a>, but there are many other questions in cell biology where this could be applied.<a href="https://doi.org/10.1038/s41467-023-36304-7" rel="nofollow noopener noreferrer" target="_blank">https://doi.org/10.1038/s41467-023-36304-7</a><a href="https://mastodon.social/tags/CellBiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#CellBiology</a> <a href="https://mastodon.social/tags/StructuralBiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#StructuralBiology</a> <a href="https://mastodon.social/tags/ElectronMiscroscopy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ElectronMiscroscopy</a> <a href="https://mastodon.social/tags/MembraneTraffic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#MembraneTraffic</a>

Stephen RoyleInteresting <a href="https://mastodon.social/tags/preprint" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#preprint</a> from Inoue lab showing that clathrin-mediated <a href="https://mastodon.social/tags/endocytosis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#endocytosis</a> can be induced through recruitment of a protein fragment containing AP-2 binding motifs to the plasma membrane. This is similar to the hot-wiring method that <a href="https://mstdn.science/@roylelab" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@roylelab</a> developed but the induction mechanism seems to be quite different!I missed this when it was posted a few weeks ago.<a href="https://www.biorxiv.org/content/10.1101/2022.12.31.522383v1" rel="nofollow noopener noreferrer" target="_blank">https://www.biorxiv.org/content/10.1101/2022.12.31.522383v1</a><a href="https://mastodon.social/tags/CellBiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#CellBiology</a> <a href="https://mastodon.social/tags/PreprintOTD" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#PreprintOTD</a> <a href="https://mastodon.social/tags/MembraneTraffic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#MembraneTraffic</a>

Mary Munson<a href="https://mstdn.social/tags/Introduction" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Introduction</a>: I am curious about how proteins and membranes work in cells to deliver cargos. Multidisciplinary lab (with great collaborators) at UMass Chan Medical School <a href="https://mstdn.social/tags/MembraneTraffic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#MembraneTraffic</a> <a href="https://mstdn.social/tags/Biochemistry" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Biochemistry</a> <a href="https://mstdn.social/tags/StructuralBiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#StructuralBiology</a> <a href="https://mstdn.social/tags/CryoEM" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#CryoEM</a> <a href="https://mstdn.social/tags/Biophysics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Biophysics</a> <a href="https://mstdn.social/tags/CellBiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#CellBiology</a> <a href="https://mstdn.social/tags/Genetics" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Genetics</a> <a href="https://mstdn.social/tags/Immunology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Immunology</a> <a href="https://mstdn.social/tags/Exocytosis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Exocytosis</a> <a href="https://mstdn.social/tags/Endocytosis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Endocytosis</a> <a href="https://mstdn.social/tags/MembraneFusion" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#MembraneFusion</a> Also passionate to increase diversity, equity, inclusion and belonging in <a href="https://mstdn.social/tags/Science" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Science</a> <a href="https://mstdn.social/tags/Academia" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Academia</a> <a href="https://mstdn.social/tags/DiversityInSTEM" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#DiversityInSTEM</a> <a href="https://mstdn.social/tags/WomenInSTEM" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#WomenInSTEM</a>.

Francesca BottanelliTwitter (and <a href="https://mstdn.science/tags/mastodon" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#mastodon</a>) <a href="https://mstdn.science/tags/cellbio" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#cellbio</a> <a href="https://mstdn.science/tags/membrane" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#membrane</a> community! Membrane seminars are back this Thu 5 pm (Berlin/Barcelona time). This week a bit of <a href="https://mstdn.science/tags/neuron" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#neuron</a> and <a href="https://mstdn.science/tags/endocytosis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#endocytosis</a> with @DomenicoAzTe from @VolkerHaucke's lab and <a href="https://mstdn.science/tags/Rab" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Rab</a> <a href="https://mstdn.science/tags/GTPases" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#GTPases</a> <a href="https://mstdn.science/tags/mitosis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#mitosis</a> with Stéphanie Miserey @institut_curie!

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