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The EMBO Journal<a href="https://sciencemastodon.com/tags/RZZ" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#RZZ</a>-<a href="https://sciencemastodon.com/tags/Spindly" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Spindly</a> complex and <a href="https://sciencemastodon.com/tags/CENPE" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#CENPE</a> (<a href="https://sciencemastodon.com/tags/kinesin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#kinesin</a>-7) are intimately connected and reciprocally required for their own <a href="https://sciencemastodon.com/tags/kinetochore" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#kinetochore</a> recruitment, <a href="https://sciencemastodon.com/tags/dynein" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#dynein</a>/#dynactin localization, and expansion of the kinetochore fibrous coronaVerena Cmentowski <a href="https://c.im/@andreamusacchio" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@andreamusacchio</a> et al <a href="https://www.embopress.org/doi/full/10.15252/embj.2023114838" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.embopress.org/doi/full/10.15252/embj.2023114838</a>

The EMBO JournalHEATR5B associates with <a href="https://sciencemastodon.com/tags/dynein" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#dynein</a>-<a href="https://sciencemastodon.com/tags/dynactin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#dynactin</a> and promotes motility of AP1-bound <a href="https://sciencemastodon.com/tags/endosomal" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#endosomal</a> membranes Simon Bullock11 and colleagues <a href="https://bird.makeup/users/mrc_lmb" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@mrc_lmb</a> <a href="https://www.embopress.org/doi/full/10.15252/embj.2023114473" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.embopress.org/doi/full/10.15252/embj.2023114473</a>

preLightsHappy <a href="https://biologists.social/tags/FluorescenceFriday" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#FluorescenceFriday</a>! This recent <a href="https://biologists.social/tags/preprint" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#preprint</a> from the Reto Gassmann Lab (<a href="https://biologists.social/tags/i3S_UPorto" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#i3S_UPorto</a>) uncovers the role of the microtubule motor dynein in controlling the stem cell division axis in the developing C. elegans epidermis. The figure below shows severely mis-oriented metaphase spindles in a hypomorphic dynein mutant.📖 <a href="https://doi.org/10.1101/2023.09.25.559295" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://doi.org/10.1101/2023.09.25.559295</a><a href="https://biologists.social/tags/StemCells" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#StemCells</a> <a href="https://biologists.social/tags/spindle" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#spindle</a> <a href="https://biologists.social/tags/CellDivision" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#CellDivision</a> <a href="https://biologists.social/tags/dynein" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#dynein</a>

Ali TwelvetreesHello! A new intro for a new instance.I lead a research group trying to figure out axonal transport and neurodegeneration. A big emphasis on the microtubules and their motors, but really the transport of anything that doesn't have a membrane around it. For this we use a lot of single molecule methods and live cell imaging. I also post about research culture.<a href="https://biologists.social/tags/introduction" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#introduction</a> <a href="https://biologists.social/tags/kinesin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#kinesin</a> <a href="https://biologists.social/tags/dynein" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#dynein</a> <a href="https://biologists.social/tags/microtubules" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#microtubules</a> <a href="https://biologists.social/tags/neurodegeneration" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#neurodegeneration</a> <a href="https://biologists.social/tags/AxonalTransport" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#AxonalTransport</a> <a href="https://biologists.social/tags/neurobiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#neurobiology</a> <a href="https://biologists.social/tags/SingleMolecule" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#SingleMolecule</a> <a href="https://biologists.social/tags/CellBiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#CellBiology</a>

The EMBO JournalATP-induced conformational change of <a href="https://sciencemastodon.com/tags/axonemal" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#axonemal</a> outer <a href="https://sciencemastodon.com/tags/dynein" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#dynein</a> arms revealed by cryo-electron <a href="https://sciencemastodon.com/tags/tomography" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#tomography</a><a href="https://sciencemastodon.com/tags/RefereedPreprint" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#RefereedPreprint</a> via <a href="https://sciencemastodon.com/@ReviewCommons" class="u-url mention" rel="nofollow noopener noreferrer" target="_blank">@ReviewCommons</a> by Takashi Ishikawa et al<a href="https://www.embopress.org/doi/10.15252/embj.2022112466" rel="nofollow noopener noreferrer" target="_blank">https://www.embopress.org/doi/10.15252/embj.2022112466</a>

Anne StraubeRecruiting two postdocs interested in molecular motors, microtubule organisation, live cell imaging, protein biochemistry, and/or single molecule biophysics <a href="https://mstdn.science/tags/jobs" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#jobs</a> <a href="https://mstdn.science/tags/postdoc" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#postdoc</a> Apply here: <a href="https://tinyurl.com/4svc8cc9" rel="nofollow noopener noreferrer" target="_blank">https://tinyurl.com/4svc8cc9</a> Get in touch with any Qs. <a href="https://mstdn.science/tags/kinesin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#kinesin</a> <a href="https://mstdn.science/tags/dynein" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#dynein</a>

preLightsTo move or not to move: A novel in vitro assay successfully recreates intracellular bidirectional cargo transport.📜 <a href="https://prelights.biologists.com/highlights/vesicles-driven-by-dynein-and-kinesin-exhibit-directional-reversals-without-external-regulators/" rel="nofollow noopener noreferrer" target="_blank">https://prelights.biologists.com/highlights/vesicles-driven-by-dynein-and-kinesin-exhibit-directional-reversals-without-external-regulators/</a>First <a href="https://mstdn.science/tags/preLight" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#preLight</a> from Divya Pathak who covers a <a href="https://mstdn.science/tags/preprint" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#preprint</a> from the Diez and Santen labs, led by Ashwin D'Souza. Includes comments from the preprint authors 👀<a href="https://mstdn.science/tags/vesicles" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#vesicles</a> <a href="https://mstdn.science/tags/transport" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#transport</a> <a href="https://mstdn.science/tags/cytoskeleton" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#cytoskeleton</a> <a href="https://mstdn.science/tags/dynein" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#dynein</a> <a href="https://mstdn.science/tags/kinesin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#kinesin</a>

Anne StraubeAlso looking for a cell biology postdoc for which we have nice toys too: <a href="https://atsv7.wcn.co.uk/search_engine/jobs.cgi?owner=5062452&ownertype=fair&jcode=1888948&vt_template=1457&adminview=1" rel="nofollow noopener noreferrer" target="_blank">https://atsv7.wcn.co.uk/search_engine/jobs.cgi?owner=5062452&ownertype=fair&jcode=1888948&vt_template=1457&adminview=1</a> <a href="https://mstdn.science/tags/postdoc" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#postdoc</a> <a href="https://mstdn.science/tags/kinesin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#kinesin</a> <a href="https://mstdn.science/tags/dynein" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#dynein</a> <a href="https://mstdn.science/tags/microtubules" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#microtubules</a> <a href="https://mstdn.science/tags/latticelightsheet" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#latticelightsheet</a> <a href="https://mstdn.science/tags/microscopy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#microscopy</a>

Ali TwelvetreesHello <a href="https://mastodon.social/tags/ScienceMastodon" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#ScienceMastodon</a>! I am a molecular and cellular neurobiologist leading a research group trying to figure out <a href="https://mastodon.social/tags/AxonalTransport" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#AxonalTransport</a> & <a href="https://mastodon.social/tags/neurodegeneration" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#neurodegeneration</a>. A big emphasis on <a href="https://mastodon.social/tags/microtubules" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#microtubules</a>, <a href="https://mastodon.social/tags/kinesin" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#kinesin</a> and <a href="https://mastodon.social/tags/dynein" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#dynein</a>, but really the transport of anything that doesn't have a membrane around it. We use a lot of <a href="https://mastodon.social/tags/SingleMolecule" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#SingleMolecule</a> methods and <a href="https://mastodon.social/tags/LiveCellImaging" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#LiveCellImaging</a>.I also post about <a href="https://mastodon.social/tags/researchculture" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#researchculture</a>, particularly how we can better invest in people so they can do great science.<a href="https://mastodon.social/tags/introduction" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#introduction</a>

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