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#Creatinine

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muıııo

A month ago, my blood test results showed that I'm perfect...

EXCEPT for an elevated #creatinine, which, in effect, decreased the value of my eGFR, which is used to determine kidney function. So the doctor said I should get checked by a nephrologist. I, however, had been taking high doses of #creatine for a while, which is shown to cause just that benign side effect. I stopped the supplement and next week I'm gonna ask for new blood tests.

Anyone else with similar experience?

Public
AMPEL-CDSS

Unadjusted Creatinine Hinders Females to Get New Liver

- Standard mathematical conversion of disadvantages females in liver transplantation prioritization

- We investigated options to reduce this gender inequality

- We identified 72 of 650 (11%) females with an original score < 20, for whom the adjusted female-as-male MELD score would be >20, thus giving them a better chance to receive a

doi.org/10.3390/jpm13060963

Revising the MELD Score to Address Sex-Bias in Liver Transplant Prioritization for a German Cohort Abstract: (1) Background: Prioritization of patients for liver transplantation in Germany relies on the MELD (model for end-stage liver disease) scoring system that does not consider the patient’s sex. Many studies have shown that women are disadvantaged by the MELD score. Using a large patient cohort from a German liver transplant centre, we investigated options to reduce gender inequality in the patient prioritization for liver transplantation. (2) Methods: We calculated female-as-male MELD scores in our cohort by substituting the serum creatinine of a female patient with that of their male equivalent to test for the fairness of the scores. We investigated the effects of the female-as-male scores compared to the original MELD score of 1759 patients listed for liver transplantation. (3) Results: Serum creatinine sex correction (female-as-male) for MELD scores added up to 5.4 points in females, while the median changed by +1.6 points for females. We identified 72 females with an original MELD score < 20, for whom the adjusted female-as-male MELD score would be >20, thus giving them a better chance to receive a liver transplant. (4) Conclusions: Mathematical conversion of female to male creatinine concentrations identified disadvantages in liver transplantation prioritization for females and ascertained MELD 3.0 as having high potential to compensate for these inequalities.
#LTx#SexBias#GenderBias
Public
AMPEL-CDSS

Today we also publish new data on the laboratory parameter serum creatinine and its use in staging of acute kidney injury:

- Women and elderly patients are systematically underdiagnosed

- A sex- and age-adapted approach is necessary to address this discrimination

Our aim is to automatically identify undetected medical conditions and integrate them into the clinicians' digital workflow.

doi.org/10.3390/jcm12031092

2/2

Article and Abstract of the article "Laboratoy Diagnostic of Acute Kidney Injury and Its Progression: Risk of Underdiagnosis in Female and Elderly Patients"
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