Tamar Sofer<p><a href="https://toot.community/tags/JustOneFigure" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>JustOneFigure</span></a> from a recently published paper: the association of a polygenic risk score for (continuous) sleep duration with cognitive outcomes. Higher values of the PRS have protective association against mild cognitive impairment (MCI) in individuals who are categorized as “short” and “normal” sleepers, but is associated with increased MCI risk in individuals categorized as “Long sleepers” — self reported to sleep more than 9 hours a night. <a href="https://toot.community/tags/PolygenicRiskScore" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>PolygenicRiskScore</span></a> <a href="https://toot.community/tags/Sleep" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Sleep</span></a> <a href="https://toot.community/tags/CognitiveAging" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>CognitiveAging</span></a></p>
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#cognitiveaging
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Hwamee Oh<p>Predictors of longitudinal cognitive ageing from age 70 to 82 including <a href="https://mastodon.online/tags/APOEe4" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>APOEe4</span></a> status, early-life and <a href="https://mastodon.online/tags/lifestyle" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>lifestyle</span></a> factors: the Lothian Birth Cohort 1936</p><p>APOE4 status explains the majority of variance in cognitive aging (but not much in a verbal domain) when early-life and lifestyle factors are included in the same model.</p><p>(Open Access)<br><a href="https://www.nature.com/articles/s41380-022-01900-4" rel="nofollow noopener" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">nature.com/articles/s41380-022</span><span class="invisible">-01900-4</span></a></p><p><a href="https://mastodon.online/tags/CognitiveAging" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>CognitiveAging</span></a> <a href="https://mastodon.online/tags/Apoe4" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Apoe4</span></a> <a href="https://mastodon.online/tags/earlylifefactors" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>earlylifefactors</span></a> <a href="https://mastodon.online/tags/lifestyle" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>lifestyle</span></a></p>
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