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PLOS BiologySecretion of <a href="https://fediscience.org/tags/rhoptry" class="mention hashtag" rel="nofollow noopener" target="_blank">#rhoptry</a> factors is essential for invasion by <a href="https://fediscience.org/tags/Apicomplexan" class="mention hashtag" rel="nofollow noopener" target="_blank">#Apicomplexan</a> <a href="https://fediscience.org/tags/parasites" class="mention hashtag" rel="nofollow noopener" target="_blank">#parasites</a>. @RouaaBc @gaelle_lentini @SoldatiLabToxo &co identify <a href="https://fediscience.org/tags/Toxoplasma" class="mention hashtag" rel="nofollow noopener" target="_blank">#Toxoplasma</a> RDF3 as crucial for invasion, priming microtubule-associated vesicles for rhoptry discharge <a href="https://fediscience.org/tags/PLOSBiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#PLOSBiology</a> <a href="https://plos.io/3Z4bbNx" rel="nofollow noopener" translate="no" target="_blank">https://plos.io/3Z4bbNx</a>

CellBioNewsAdvanced imaging reveals how a <a href="https://scientificnetwork.de/tags/parasitic" class="mention hashtag" rel="nofollow noopener" target="_blank">#parasitic</a> 'kiss' alters <a href="https://scientificnetwork.de/tags/cell" class="mention hashtag" rel="nofollow noopener" target="_blank">#cell</a> <a href="https://scientificnetwork.de/tags/metabolism" class="mention hashtag" rel="nofollow noopener" target="_blank">#metabolism</a>.<a href="https://scientificnetwork.de/tags/Toxoplasma" class="mention hashtag" rel="nofollow noopener" target="_blank">#Toxoplasma</a> <a href="https://scientificnetwork.de/tags/optical_metabolic_imaging" class="mention hashtag" rel="nofollow noopener" target="_blank">#optical_metabolic_imaging</a> <a href="https://scientificnetwork.de/tags/apicomplexan" class="mention hashtag" rel="nofollow noopener" target="_blank">#apicomplexan</a><a href="https://phys.org/news/2024-07-advanced-imaging-reveals-parasitic-cell.html" rel="nofollow noopener" translate="no" target="_blank">https://phys.org/news/2024-07-advanced-imaging-reveals-parasitic-cell.html</a>

CellBioNews<a href="https://scientificnetwork.de/tags/CLAMP" class="mention hashtag" rel="nofollow noopener" target="_blank">#CLAMP</a> complex helps <a href="https://scientificnetwork.de/tags/parasites" class="mention hashtag" rel="nofollow noopener" target="_blank">#parasites</a> enter human <a href="https://scientificnetwork.de/tags/cells" class="mention hashtag" rel="nofollow noopener" target="_blank">#cells</a>. <a href="https://scientificnetwork.de/tags/Apicomplexan" class="mention hashtag" rel="nofollow noopener" target="_blank">#Apicomplexan</a> <a href="https://scientificnetwork.de/tags/micronemes" class="mention hashtag" rel="nofollow noopener" target="_blank">#micronemes</a> <a href="https://scientificnetwork.de/tags/Toxoplasma" class="mention hashtag" rel="nofollow noopener" target="_blank">#Toxoplasma</a><a href="https://phys.org/news/2023-10-clamp-complex-parasites-human-cells.html" rel="nofollow noopener" translate="no" target="_blank">https://phys.org/news/2023-10-clamp-complex-parasites-human-cells.html</a>

The EMBO JournalA conserved complex of microneme proteins mediates rhoptry discharge in <a href="https://sciencemastodon.com/tags/Toxoplasma" class="mention hashtag" rel="nofollow noopener" target="_blank">#Toxoplasma</a>:Sebastian Lourido and coworkers show that three <a href="https://sciencemastodon.com/tags/apicomplexan" class="mention hashtag" rel="nofollow noopener" target="_blank">#apicomplexan</a>-specific <a href="https://sciencemastodon.com/tags/microneme" class="mention hashtag" rel="nofollow noopener" target="_blank">#microneme</a> proteins form a complex essential for <a href="https://sciencemastodon.com/tags/rhoptry" class="mention hashtag" rel="nofollow noopener" target="_blank">#rhoptry</a> discharge and invasion<a href="https://www.embopress.org/doi/full/10.15252/embj.2022113155" rel="nofollow noopener" translate="no" target="_blank">https://www.embopress.org/doi/full/10.15252/embj.2022113155</a>

PLOS BiologyStudy shows that a small-molecule inhibitor of <a href="https://fediscience.org/tags/Toxoplasma" class="mention hashtag" rel="nofollow noopener" target="_blank">#Toxoplasma</a> <a href="https://fediscience.org/tags/myosin" class="mention hashtag" rel="nofollow noopener" target="_blank">#myosin</a> A reduces <a href="https://fediscience.org/tags/parasite" class="mention hashtag" rel="nofollow noopener" target="_blank">#parasite</a> motility & alters disease progression in vivo, suggesting a new approach to treating infections by <a href="https://fediscience.org/tags/apicomplexan" class="mention hashtag" rel="nofollow noopener" target="_blank">#apicomplexan</a> parasites <a href="https://fediscience.org/tags/PLOSBiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#PLOSBiology</a> <a href="https://plos.io/42ySrUG" rel="nofollow noopener" target="_blank">https://plos.io/42ySrUG</a>

PLOS BiologyToxo invasion. @MirkoSinger @MeissnerLab &co identify a protein complex containing a CRMPA/CRMPB heterodimer with multiple transmembrane domains as being essential for host cell invasion by the <a href="https://fediscience.org/tags/apicomplexan" class="mention hashtag" rel="nofollow noopener" target="_blank">#apicomplexan</a> <a href="https://fediscience.org/tags/parasite" class="mention hashtag" rel="nofollow noopener" target="_blank">#parasite</a> <a href="https://fediscience.org/tags/Toxoplasma" class="mention hashtag" rel="nofollow noopener" target="_blank">#Toxoplasma</a> gondii <a href="https://fediscience.org/tags/PLOSBiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#PLOSBiology</a> <a href="https://plos.io/3vJePMM" rel="nofollow noopener" target="_blank">https://plos.io/3vJePMM</a>

Trends in ParasitologyOur 2022 December issue <a href="https://bit.ly/2N9R8Es" rel="nofollow noopener" target="_blank">https://bit.ly/2N9R8Es</a> reviews ecoevolutionary consequences of <a href="https://mstdn.science/tags/antimalarials" class="mention hashtag" rel="nofollow noopener" target="_blank">#antimalarials</a> in <a href="https://mstdn.science/tags/mosquitoes" class="mention hashtag" rel="nofollow noopener" target="_blank">#mosquitoes</a>, <a href="https://mstdn.science/tags/apicomplexan" class="mention hashtag" rel="nofollow noopener" target="_blank">#apicomplexan</a> mitochondrial respiratory chain, <a href="https://mstdn.science/tags/trypanosomatid" class="mention hashtag" rel="nofollow noopener" target="_blank">#trypanosomatid</a> mitoribosomal biogenesis, omics discovery of <a href="https://mstdn.science/tags/fasciolosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#fasciolosis</a> vaccine, <a href="https://mstdn.science/tags/schistosome" class="mention hashtag" rel="nofollow noopener" target="_blank">#schistosome</a> purinergic halo, parasite <a href="https://mstdn.science/tags/avirulence" class="mention hashtag" rel="nofollow noopener" target="_blank">#avirulence</a> factors, & more! Cover article on <a href="https://mstdn.science/tags/diverse" class="mention hashtag" rel="nofollow noopener" target="_blank">#diverse</a> <a href="https://mstdn.science/tags/leadership" class="mention hashtag" rel="nofollow noopener" target="_blank">#leadership</a> in STEMM. TrendsTalks on key conferences <a href="https://mstdn.science/tags/ICOPA2022" class="mention hashtag" rel="nofollow noopener" target="_blank">#ICOPA2022</a>, <a href="https://mstdn.science/tags/HydraHelminths" class="mention hashtag" rel="nofollow noopener" target="_blank">#HydraHelminths</a>, <a href="https://mstdn.science/tags/TTP10" class="mention hashtag" rel="nofollow noopener" target="_blank">#TTP10</a>, & <a href="https://mstdn.science/tags/CJM4" class="mention hashtag" rel="nofollow noopener" target="_blank">#CJM4</a>. Parasite of the Month on <a href="https://mstdn.science/tags/Dicrocoelium" class="mention hashtag" rel="nofollow noopener" target="_blank">#Dicrocoelium</a> <a href="https://mstdn.science/tags/dendriticum" class="mention hashtag" rel="nofollow noopener" target="_blank">#dendriticum</a>.

Bish MarzookEarnest <a href="https://mastodon.social/tags/introduction" class="mention hashtag" rel="nofollow noopener" target="_blank">#introduction</a> incoming!I'm a <a href="https://mastodon.social/tags/parasitologist" class="mention hashtag" rel="nofollow noopener" target="_blank">#parasitologist</a> (previously: <a href="https://mastodon.social/tags/virologist" class="mention hashtag" rel="nofollow noopener" target="_blank">#virologist</a>) working in London on the <a href="https://mastodon.social/tags/apicomplexan" class="mention hashtag" rel="nofollow noopener" target="_blank">#apicomplexan</a> <a href="https://mastodon.social/tags/parasite" class="mention hashtag" rel="nofollow noopener" target="_blank">#parasite</a> <a href="https://mastodon.social/tags/Cryptosporidium" class="mention hashtag" rel="nofollow noopener" target="_blank">#Cryptosporidium</a>. I do cell biology, make <a href="https://mastodon.social/tags/organoids" class="mention hashtag" rel="nofollow noopener" target="_blank">#organoids</a>, and think a lot about host-pathogen interactions, as well as the evolution thereof!I care about a lot of things. Occasionally I do <a href="https://mastodon.social/tags/standup" class="mention hashtag" rel="nofollow noopener" target="_blank">#standup</a> <a href="https://mastodon.social/tags/comedy" class="mention hashtag" rel="nofollow noopener" target="_blank">#comedy</a> about them in exchange for free drinks and self-esteem.Learning to balance silliness w science will be the death of me/my career. Let's see which one happens first!

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