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#PASC

5 posts3 participants0 posts today

Health economic outcomes and national economic impacts associated with #LongCOVID in England and Scotland

link.springer.com/article/10.1

"This study found small improvements in EQ-5D-3L utility score in LC patients receiving care in LC clinics."

Subjective outcome I believe so prone to bias

#PASC @longcovid

SpringerLinkHealth economic outcomes and national economic impacts associated with Long COVID in England and Scotland - The European Journal of Health EconomicsBackground Two million people in the UK suffer from Long COVID (LC), imposing substantial health economic impacts. This study aimed to: 1) assess longitudinal changes in health utility scores and economic costs of LC, and number of services received at LC specialist clinics and clinic region to capture care intensity; 2) assess whether volume of services received responded to health needs; and 3) estimate the national economic impact of LC. Methods LC patients from 10 specialist clinics participated in the LOCOMOTION study. Patient-reported outcomes measures (EQ-5D-5L, C19-YRS and Health Economics Questionnaire) were completed on a digital platform. Associations were assessed between changes in economic outcomes (EQ-5D-3L utility, health economic costs) and number/type of LC specialist services received and region. Per-person values of quality-adjusted life-year losses, public sector costs, productivity losses and informal care costs were multiplied by LC prevalence to estimate national economic impacts. Results There was a statistically significant reduction in public sector costs over time. There was no significant association between the number of specialist services received and change in health utility scores. LC specialist clinic and outpatient service utilisation corresponded to health need and had significant regional variation after controlling for health need. LC is associated with a substantial economic impact nationally, estimated at £8.1 billion annually and £24.2 billion since its emergence, comparable to the annual cost of £9.4 billion for stroke. Conclusion The effectiveness of LC specialist clinic services warrants further research. The substantial national economic impact of LC warrants a nationwide LC care strategy.

"Experts call new Canadian Long COVID guidelines “contradictory” and “deeply concerning”: Guidelines recommend exercise and therapy as treatments, following attempted influence from Paul Garner"

thesicktimes.org/2025/07/08/ex

Image is from the latest Science for ME weekly update

@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC
@mecfs
#MyalgicEncephalomyelitis #ChronicFatigueSyndrome #MEcfs #CFS #PwME

Interesting new UK research:
Brain and muscle chemistry in myalgic encephalitis/ #chronicfatiguesyndrome (#MECFS) & #longCOVID: a 7T magnetic resonance spectroscopy study

nature.com/articles/s41380-025

"The changes in lactate in ME/CFS are consistent with the presence of energetic stress & mitochondrial dysfunction"

@mecfs
#MyalgicEncephalomyelitis #MEcfs #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC

Continued thread

2/
New US research:

Oxidative stress is a shared characteristic of #MECFS & #LongCOVID

pnas.org/doi/abs/10.1073/pnas.

"these results suggest a shared mechanistic basis for the systemic phenotypes of ME/CFS & LC...& effective, patient- tailored drugs might be discovered using standard lymphocyte stimulation assays"

@mecfs @longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC

🧵
Patient-reported treatment outcomes in ME/CFS & long COVID

pnas.org/doi/abs/10.1073/pnas.

"results of an ME/CFS and long COVID treatment survey with responses from 3,925 patients"

"This study underscores the symptomatic and therapeutic similarities between #MECFS & #longCOVID"

@mecfs
#MyalgicEncephalomyelitis #ChronicFatigueSyndrome #CFS #PwME @longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #LC #Covidlonghaulers #PostCovidSyndrome #longhaulers #COVIDBrain #NeuroPASC

1/

From Germany:
"These monocyte compartment perturbations were also found in PACS patients with a disease duration greater than two years, suggesting a persistent & long-term dysregulation of the monocyte subsets"

mdpi.com/1999-4915/17/6/784

Image from @s4me update

Hashtags:
@longcovid
#LongCovid #PASC #PwLC #postcovid #postcovid19 #Covidlonghaulers #PostCovidSyndrome #COVIDBrain #NeuroPASC
@covid19 #Coronavirus
#COVID19 #COVID #COVIDー19 #SARSCoV2 @novid@chirp.social #novid @novid@a.gup.pe #CovidIsNotOver
@auscovid19