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Dining and Cooking<p>Oleic acid from olive oil reduces infection-related bone loss with age</p><p>New re…<br><a href="https://vive.im/tags/dining" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>dining</span></a> <a href="https://vive.im/tags/cooking" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cooking</span></a> <a href="https://vive.im/tags/diet" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>diet</span></a> <a href="https://vive.im/tags/food" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>food</span></a> <a href="https://vive.im/tags/MediterraneanOliveOil" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MediterraneanOliveOil</span></a> <a href="https://vive.im/tags/OliveOil" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>OliveOil</span></a> #<a href="https://vive.im/tags/inflammation" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>inflammation</span></a> <a href="https://vive.im/tags/aging" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>aging</span></a> <a href="https://vive.im/tags/Antibiotic" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Antibiotic</span></a> <a href="https://vive.im/tags/Bacterial" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Bacterial</span></a> <a href="https://vive.im/tags/Bone" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Bone</span></a> <a href="https://vive.im/tags/cardiovasculardisease" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cardiovasculardisease</span></a> <a href="https://vive.im/tags/Diabetes" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Diabetes</span></a> <a href="https://vive.im/tags/ImmuneResponse" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ImmuneResponse</span></a> <a href="https://vive.im/tags/Mediterranean" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Mediterranean</span></a> <a href="https://vive.im/tags/MediterraneanDiet" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MediterraneanDiet</span></a> <a href="https://vive.im/tags/Microbiome" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Microbiome</span></a> <a href="https://vive.im/tags/MouseModel" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MouseModel</span></a> <a href="https://vive.im/tags/Olive" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Olive</span></a> <a href="https://vive.im/tags/Osteoclast" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Osteoclast</span></a> <a href="https://vive.im/tags/osteoporosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>osteoporosis</span></a> <a href="https://vive.im/tags/Periodontitis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Periodontitis</span></a> <a href="https://vive.im/tags/Research" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Research</span></a> <a href="https://vive.im/tags/saturatedfats" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>saturatedfats</span></a> <a href="https://vive.im/tags/stress" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>stress</span></a> <a href="https://vive.im/tags/teeth" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>teeth</span></a><br><a href="https://www.diningandcooking.com/2154139/oleic-acid-from-olive-oil-reduces-infection-related-bone-loss-with-age/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">diningandcooking.com/2154139/o</span><span class="invisible">leic-acid-from-olive-oil-reduces-infection-related-bone-loss-with-age/</span></a></p>
Dining & Cooking<p>Oleic acid from olive oil reduces infection-related bone loss with age <a href="https://www.diningandcooking.com/2154139/oleic-acid-from-olive-oil-reduces-infection-related-bone-loss-with-age/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">diningandcooking.com/2154139/o</span><span class="invisible">leic-acid-from-olive-oil-reduces-infection-related-bone-loss-with-age/</span></a> #<a href="https://vive.im/tags/inflammation" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>inflammation</span></a> <a href="https://vive.im/tags/aging" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>aging</span></a> <a href="https://vive.im/tags/Antibiotic" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Antibiotic</span></a> <a href="https://vive.im/tags/Bacterial" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Bacterial</span></a> <a href="https://vive.im/tags/Bone" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Bone</span></a> <a href="https://vive.im/tags/CardiovascularDisease" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>CardiovascularDisease</span></a> <a href="https://vive.im/tags/Diabetes" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Diabetes</span></a> <a href="https://vive.im/tags/diet" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>diet</span></a> <a href="https://vive.im/tags/ImmuneResponse" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ImmuneResponse</span></a> <a href="https://vive.im/tags/Mediterranean" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Mediterranean</span></a> <a href="https://vive.im/tags/MediterraneanDiet" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MediterraneanDiet</span></a> <a href="https://vive.im/tags/MediterraneanOliveOil" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MediterraneanOliveOil</span></a> <a href="https://vive.im/tags/Microbiome" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Microbiome</span></a> <a href="https://vive.im/tags/MouseModel" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MouseModel</span></a> <a href="https://vive.im/tags/Olive" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Olive</span></a> <a href="https://vive.im/tags/OliveOil" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>OliveOil</span></a> <a href="https://vive.im/tags/Osteoclast" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Osteoclast</span></a> <a href="https://vive.im/tags/osteoporosis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>osteoporosis</span></a> <a href="https://vive.im/tags/Periodontitis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Periodontitis</span></a> <a href="https://vive.im/tags/Research" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Research</span></a> <a href="https://vive.im/tags/SaturatedFats" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>SaturatedFats</span></a> <a href="https://vive.im/tags/stress" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>stress</span></a> <a href="https://vive.im/tags/teeth" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>teeth</span></a></p>
UK<p><a href="https://www.europesays.com/uk/171894/" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="">europesays.com/uk/171894/</span><span class="invisible"></span></a> Study reveals the genetic underpinnings of a rare and aggressive ovarian cancer <a href="https://pubeurope.com/tags/Cancer" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cancer</span></a> <a href="https://pubeurope.com/tags/carcinoma" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>carcinoma</span></a> <a href="https://pubeurope.com/tags/Cell" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cell</span></a> <a href="https://pubeurope.com/tags/FallopianTube" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>FallopianTube</span></a> <a href="https://pubeurope.com/tags/Gene" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Gene</span></a> <a href="https://pubeurope.com/tags/Genes" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Genes</span></a> <a href="https://pubeurope.com/tags/Genetic" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Genetic</span></a> <a href="https://pubeurope.com/tags/Genetics" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Genetics</span></a> <a href="https://pubeurope.com/tags/Medicine" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Medicine</span></a> <a href="https://pubeurope.com/tags/MouseModel" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MouseModel</span></a> <a href="https://pubeurope.com/tags/OrganicChemistry" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>OrganicChemistry</span></a> <a href="https://pubeurope.com/tags/OvarianCancer" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>OvarianCancer</span></a> <a href="https://pubeurope.com/tags/Ovaries" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Ovaries</span></a> <a href="https://pubeurope.com/tags/Pathology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Pathology</span></a> <a href="https://pubeurope.com/tags/Prostate" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Prostate</span></a> <a href="https://pubeurope.com/tags/ProstateCancer" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ProstateCancer</span></a> <a href="https://pubeurope.com/tags/Research" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Research</span></a> <a href="https://pubeurope.com/tags/Science" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Science</span></a> <a href="https://pubeurope.com/tags/Tumor" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Tumor</span></a> <a href="https://pubeurope.com/tags/UK" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>UK</span></a> <a href="https://pubeurope.com/tags/UnitedKingdom" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>UnitedKingdom</span></a></p>
Rhyothemis<p>"Human TRPA1 activity is suppressed by caffeine (Figure&nbsp;10), whereas in mice this ion channel is stimulated by caffeine."</p><p><a href="https://doi.org/10.1177/0960327119877460" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">doi.org/10.1177/09603271198774</span><span class="invisible">60</span></a></p><p><a href="https://zeroes.ca/tags/MouseVsHuman" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MouseVsHuman</span></a> <a href="https://zeroes.ca/tags/MouseModel" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MouseModel</span></a> <a href="https://zeroes.ca/tags/Mice" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Mice</span></a> <a href="https://zeroes.ca/tags/TRPA1" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>TRPA1</span></a> <a href="https://zeroes.ca/tags/TRPchannels" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>TRPchannels</span></a> <a href="https://zeroes.ca/tags/caffeine" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>caffeine</span></a> <a href="https://zeroes.ca/tags/pain" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>pain</span></a> <a href="https://zeroes.ca/tags/neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>neuroscience</span></a> <a href="https://zeroes.ca/tags/biology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>biology</span></a></p>
Fabrizio Musacchio<p>Our new <a href="https://sigmoid.social/tags/preprint" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>preprint</span></a> on <a href="https://sigmoid.social/tags/ThreePhoton" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ThreePhoton</span></a> in vivo <a href="https://sigmoid.social/tags/imaging" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>imaging</span></a> of <a href="https://sigmoid.social/tags/neurons" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>neurons</span></a> and <a href="https://sigmoid.social/tags/glia" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>glia</span></a> 🔬 in the medial prefrontal cortex (<a href="https://sigmoid.social/tags/mPFC" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>mPFC</span></a>) 🧠 with sub-cellular resolution 🔍 is out! Check it out on <a href="https://sigmoid.social/tags/biorxiv" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>biorxiv</span></a>:</p><p>🌍 <a href="https://www.biorxiv.org/content/10.1101/2024.08.28.610026v1" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">biorxiv.org/content/10.1101/20</span><span class="invisible">24.08.28.610026v1</span></a></p><p><a href="https://sigmoid.social/tags/Neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neuroscience</span></a> <a href="https://sigmoid.social/tags/multiphoton" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>multiphoton</span></a> <a href="https://sigmoid.social/tags/3p" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>3p</span></a> vs. <a href="https://sigmoid.social/tags/2p" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>2p</span></a> <a href="https://sigmoid.social/tags/twophoton" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>twophoton</span></a> <a href="https://sigmoid.social/tags/hippocampus" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>hippocampus</span></a> <a href="https://sigmoid.social/tags/drosophila" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>drosophila</span></a> <a href="https://sigmoid.social/tags/MouseModel" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MouseModel</span></a> <a href="https://sigmoid.social/tags/DeepImaging" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>DeepImaging</span></a> <a href="https://sigmoid.social/tags/preprintalert" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>preprintalert</span></a> <a href="https://sigmoid.social/tags/DZNE" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>DZNE</span></a> <span class="h-card" translate="no"><a href="https://social.bund.de/@dzne" class="u-url mention" rel="nofollow noopener" target="_blank">@<span>dzne</span></a></span></p>
Fabrizio Musacchio<p>DAMM, Detect Any <a href="https://sigmoid.social/tags/MouseModel" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MouseModel</span></a> 🐭, has just been released 👌 It’s a robustly validated mouse detector that excels in generalization, tracking mice in complex social and experimental settings with zero to minimal setup-specific training </p><p>🌍 <a href="http://web.eecs.umich.edu/gkaul/DAMM" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">http://</span><span class="">web.eecs.umich.edu/gkaul/DAMM</span><span class="invisible"></span></a><br>🌍 GitHub: <a href="http://github.com/backprop64/DAMM" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">http://</span><span class="">github.com/backprop64/DAMM</span><span class="invisible"></span></a><br>📒 Kaul et al. (2024) <a href="http://biorxiv.org/content/10.1101/2024.01.18.576153v1" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">http://</span><span class="ellipsis">biorxiv.org/content/10.1101/20</span><span class="invisible">24.01.18.576153v1</span></a></p><p><a href="https://sigmoid.social/tags/BehavioralScience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>BehavioralScience</span></a> <a href="https://sigmoid.social/tags/behavioralanalysis" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>behavioralanalysis</span></a> <a href="https://sigmoid.social/tags/neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>neuroscience</span></a> <a href="https://sigmoid.social/tags/machinelearning" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>machinelearning</span></a></p>
Daniel Caron<p>Macrophages are essential immune cells that reside in all tissues. Some macrophages arise from monocytes in the blood, but during fetal development they also come from a unique pathway!</p><p>We still have a lot to learn, but here I'll describe how Zhao et al. (2023) used mouse models to uncover hints about which progenitor cells create tissue-macrophages.</p><p><a href="https://doi.org/10.1016/j.celrep.2023.113364" rel="nofollow noopener" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">doi.org/10.1016/j.celrep.2023.</span><span class="invisible">113364</span></a></p><p><a href="https://genomic.social/tags/Macrophages" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Macrophages</span></a> <a href="https://genomic.social/tags/MouseModel" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MouseModel</span></a> <a href="https://genomic.social/tags/Immunology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Immunology</span></a> <a href="https://genomic.social/tags/Immunity" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Immunity</span></a> <a href="https://genomic.social/tags/scRNAseq" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>scRNAseq</span></a> <a href="https://genomic.social/tags/FlowCytometry" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>FlowCytometry</span></a> <a href="https://genomic.social/tags/Research" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Research</span></a> <a href="https://genomic.social/tags/JournalArticle" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>JournalArticle</span></a> <a href="https://genomic.social/tags/JournalClub" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>JournalClub</span></a></p><p>1/9🧵</p>
Daniel Caron<p>Really cool application of Infinity Flow to <a href="https://genomic.social/tags/MouseModel" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MouseModel</span></a> <a href="https://genomic.social/tags/Tcells" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Tcells</span></a>, which allows readout/prediction of &gt;200 surface epitopes on single cells via <a href="https://genomic.social/tags/FlowCytometry" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>FlowCytometry</span></a>. </p><p><a href="https://doi.org/10.1016/j.immuni.2023.06.005" rel="nofollow noopener" target="_blank"><span class="invisible">https://</span><span class="ellipsis">doi.org/10.1016/j.immuni.2023.</span><span class="invisible">06.005</span></a> </p><p>By <span class="h-card"><a href="https://mstdn.science/@maxevrard" class="u-url mention" rel="nofollow noopener" target="_blank">@<span>maxevrard</span></a></span> <br><a href="https://genomic.social/tags/Immunology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Immunology</span></a> <a href="https://genomic.social/tags/TissueImmunity" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>TissueImmunity</span></a></p>
WikiPathways<p>A novel orthotopic mouse model replicates human lung cancer cachexia. <a href="https://doi.org/10.1002/jcsm.13222" rel="nofollow noopener" target="_blank"><span class="invisible">https://</span><span class="">doi.org/10.1002/jcsm.13222</span><span class="invisible"></span></a> <a href="https://fosstodon.org/tags/CancerCachexia" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>CancerCachexia</span></a> <a href="https://fosstodon.org/tags/LungCancer" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>LungCancer</span></a> <a href="https://fosstodon.org/tags/MuscleWasting" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MuscleWasting</span></a> <a href="https://fosstodon.org/tags/MouseModel" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MouseModel</span></a> <a href="https://fosstodon.org/tags/OrthotopicMouseModel" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>OrthotopicMouseModel</span></a></p>
Dr. John Barentine FRAS<p>New results in a mouse model "demonstrate the rapid and potent effects of [artificial light at night] on cerebrovascular networks, highlighting the importance of ALAN mitigation in the context of health and cerebrovascular disease."</p><p><a href="https://www.cell.com/iscience/fulltext/S2589-0042(23)01073-8" rel="nofollow noopener" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">cell.com/iscience/fulltext/S25</span><span class="invisible">89-0042(23)01073-8</span></a></p><p><a href="https://astrodon.social/tags/Neuroscience" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Neuroscience</span></a> <a href="https://astrodon.social/tags/Chronobiology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Chronobiology</span></a> <a href="https://astrodon.social/tags/MouseModel" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MouseModel</span></a> <a href="https://astrodon.social/tags/ModelOrganism" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ModelOrganism</span></a> <a href="https://astrodon.social/tags/Cerebrovascular" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>Cerebrovascular</span></a> <a href="https://astrodon.social/tags/ALAN" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ALAN</span></a></p>
UC Davis Mouse Biology<p><a href="https://mstdn.science/tags/scientists" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>scientists</span></a> previously believed silent synapses were only present during early development; however, <a href="https://mstdn.science/tags/mousemodel" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>mousemodel</span></a> research found that about 30% of all synapses in the cortex are silent.</p><p><a href="https://scitechdaily.com/surprising-discovery-mit-neuroscientists-find-that-adult-brain-is-filled-with-millions-of-silent-synapses/" rel="nofollow noopener" target="_blank"><span class="invisible">https://</span><span class="ellipsis">scitechdaily.com/surprising-di</span><span class="invisible">scovery-mit-neuroscientists-find-that-adult-brain-is-filled-with-millions-of-silent-synapses/</span></a></p>
Mutant Mouse Reso&Rsrch Center<p><a href="https://mstdn.science/tags/scientists" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>scientists</span></a> previously believed silent synapses were only present during early development; however, <a href="https://mstdn.science/tags/mousemodel" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>mousemodel</span></a> research found that about 30% of all synapses in the cortex are silent.</p><p><a href="https://scitechdaily.com/surprising-discovery-mit-neuroscientists-find-that-adult-brain-is-filled-with-millions-of-silent-synapses/" rel="nofollow noopener" target="_blank"><span class="invisible">https://</span><span class="ellipsis">scitechdaily.com/surprising-di</span><span class="invisible">scovery-mit-neuroscientists-find-that-adult-brain-is-filled-with-millions-of-silent-synapses/</span></a></p>
UC Davis Mouse Biology<p>With new data analysis coming out showing 4 main subtypes of <a href="https://mstdn.science/tags/longcovid" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>longcovid</span></a>, we're always here to help <a href="https://mstdn.science/tags/mousemodel" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>mousemodel</span></a> development to address these areas specifically.</p><p><a href="https://www.nature.com/articles/s41591-022-02116-3?utm_medium=affiliate&amp;utm_source=commission_junction&amp;utm_campaign=CONR_PF018_ECOM_GL_PHSS_ALWYS_DEEPLINK&amp;utm_content=textlink&amp;utm_term=PID100098473&amp;CJEVENT=ce867ee5968611ed828502d50a1c0e0b" rel="nofollow noopener" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">nature.com/articles/s41591-022</span><span class="invisible">-02116-3?utm_medium=affiliate&amp;utm_source=commission_junction&amp;utm_campaign=CONR_PF018_ECOM_GL_PHSS_ALWYS_DEEPLINK&amp;utm_content=textlink&amp;utm_term=PID100098473&amp;CJEVENT=ce867ee5968611ed828502d50a1c0e0b</span></a></p>
DMM Journal<p>Meet Dr Emily Warren, 1st author of new <a href="https://mstdn.science/tags/OpenAccess" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>OpenAccess</span></a> paper from Dr Eric Morrow's lab at <a href="https://mstdn.science/tags/BrownUniversity" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>BrownUniversity</span></a> </p><p>They developed the 1st lab model of 17q12 deletion syndrome, a copy number variant disorder associated with <a href="https://mstdn.science/tags/neurodevelopmental" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>neurodevelopmental</span></a> disorders and <a href="https://mstdn.science/tags/RenalCysts" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>RenalCysts</span></a> and <a href="https://mstdn.science/tags/diabetes" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>diabetes</span></a> syndrome. The <a href="https://mstdn.science/tags/MouseModel" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>MouseModel</span></a> recapitulated many features of the human disorder &amp; will be used to guide <a href="https://mstdn.science/tags/clinical" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>clinical</span></a> &amp; <a href="https://mstdn.science/tags/mechanistic" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>mechanistic</span></a> studies</p><p>Interview &amp; research article: <br>👩🏻‍🔬<a href="https://journals.biologists.com/dmm/article/15/12/dmm050017/285934/" rel="nofollow noopener" target="_blank"><span class="invisible">https://</span><span class="ellipsis">journals.biologists.com/dmm/ar</span><span class="invisible">ticle/15/12/dmm050017/285934/</span></a><br>📰<a href="https://journals.biologists.com/dmm/article/15/12/dmm049752/285935/" rel="nofollow noopener" target="_blank"><span class="invisible">https://</span><span class="ellipsis">journals.biologists.com/dmm/ar</span><span class="invisible">ticle/15/12/dmm049752/285935/</span></a></p>
Pei-Chi Wei<p><a href="https://genomic.social/tags/introduction" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>introduction</span></a> I am Peggy Wei, an <a href="https://genomic.social/tags/NewPI" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>NewPI</span></a> (3 years old) at <a href="https://genomic.social/tags/DKFZ" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>DKFZ</span></a> . I am also a mother with two children, and a cooking lover. We use <a href="https://genomic.social/tags/omics" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>omics</span></a> and <a href="https://genomic.social/tags/mousemodel" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>mousemodel</span></a> to understand genome integrity and somatic mosaicism in the developing <a href="https://genomic.social/tags/brain" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>brain</span></a>. Other interests include but not limited to <a href="https://genomic.social/tags/neuropsychiatric" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>neuropsychiatric</span></a> disorders , <a href="https://genomic.social/tags/cancer" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cancer</span></a> origin, DNA <a href="https://genomic.social/tags/replication" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>replication</span></a>, <a href="https://genomic.social/tags/CNV" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>CNV</span></a>, and <a href="https://genomic.social/tags/singlemolecule" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>singlemolecule</span></a> view of DNA damage. I transferred from the other server (@braingenome@scicomm.xyz) because I feel closer to genomics.</p>
Les Sutton<p>Hi <a href="https://fediscience.org/tags/ScienceMastodon" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>ScienceMastodon</span></a> - my lab's most recent findings just hit preprint here: <a href="https://www.sciencedirect.com/science/article/pii/S0022202X22018887?via%3Dihub" rel="nofollow noopener" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">sciencedirect.com/science/arti</span><span class="invisible">cle/pii/S0022202X22018887?via%3Dihub</span></a></p><p>We discovered a <a href="https://fediscience.org/tags/mousemodel" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>mousemodel</span></a> for examining <a href="https://fediscience.org/tags/cSCC" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cSCC</span></a> where <a href="https://fediscience.org/tags/mice" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>mice</span></a> with epidermal deficiency of <a href="https://fediscience.org/tags/KDM6A" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>KDM6A</span></a> and <a href="https://fediscience.org/tags/P53" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>P53</span></a> show 100% penetrant, spontaneous cSCC development within a year!</p><p><a href="https://fediscience.org/tags/dermatology" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>dermatology</span></a> and <a href="https://fediscience.org/tags/skincancer" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>skincancer</span></a> have very few models to study cSCC in mice and our lab found one!</p><p><a href="https://fediscience.org/tags/cancer" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>cancer</span></a> <a href="https://fediscience.org/tags/epigenetics" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>epigenetics</span></a> <a href="https://fediscience.org/tags/academicchatter" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>academicchatter</span></a> <a href="https://fediscience.org/tags/derm" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>derm</span></a> <a href="https://fediscience.org/tags/tumorsuppressors" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>tumorsuppressors</span></a> <a href="https://fediscience.org/tags/tumor" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>tumor</span></a> <a href="https://fediscience.org/tags/scicomm" class="mention hashtag" rel="nofollow noopener" target="_blank">#<span>scicomm</span></a></p>