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#molecularbiology

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Just moved to Fosstodon! #introduction

Dad and husband in #Pennsylvania. I teach #biochemistry, #molecularbiology, and #microbiology (and #humanities) in #highered.

Daily #Emacs user since the late 80s, #GNU #Linux on and off since the 90s. Strictly #FreeSoftware since 2010s. #Debian, #GrapheneOS, #OrgMode and #Emacs for teaching and research.

#Japanese #日本語, #francais, y #espanol roto. #DnD and #books. Love #camping #hiking #walking #cycling #coding #elisp

Continued thread

5/8 🔬🧩 The simulated Kd values for the Evening Complex binding overlapped with the empirical data on its DNA-binding protein LUX ✅

Simulated CCA1/LHY bound much less tightly than its measured Kd. Likely, the plant regulates these proteins in ways we haven’t modelled: future research directions!

We point to lots specific hypotheses, data and knowledge gaps, see Dataset EV1. We’re not pursuing any of them.

#Introduction

Hi there 👋,

I'm Brad, I'm new to Chinwag, but not new to fedi (been here since late 2018).

I'm keen to chat about music, it was a huge part of my life way back when I studied it at uni. I'll give almost anything a good listen but genres I've spent the most time with might be: #Jazz (#HardBop, #PostBop, #FreeJazz), #ClassicalMusic (#ChamberMusic, #Orchestral, #Baroque), #Rock (#AlternativeRock, #PowerPop, #NewWave, #ProtoPunk, #ElectronicRock).

I'm very keen to learn whatever I can from folks who're into the earth and life sciences. #Geology, #Biology, #MolecularBiology, #PrebioticChemistry.

Cheers,
Brad.

Continued thread

Almost from the moment of conception, genetic mutations start to occur in our bodies, and they continue to do so through our lives. “Only in recent years has technology been sensitive enough to catalog every genetic booboo. And it’s revealed we’re riddled with errors,” writes Amber Dance for @KnowableMag. Here’s her story on the causes and consequences of these.

knowablemagazine.org/content/a

Knowable Magazine | Annual ReviewsWe are all mosaicsPicture your body: It’s a collection of cells carrying thousands of genetic mistakes accrued over a lifetime — many harmless, some bad, and at least a few that may be good for you.

“I would be quite proud to have served on the committee that designed the E. coli genome. There is, however, no way that I would admit to serving on a committee that designed the human genome. Not even a university committee could botch something that badly” David Penny, quoted in Graur et al. (2013).

And while I’m reading Philip Ball’s “How Life Works”

#evolution, #cellbiology, #genomics, #molecularbiology