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Viet Le, MPAS PA-C FACC FAHAStatin revisited.❤️‍🔥 statin vs no-statin: 25% RRR MACE ❤️‍🔥 intense statin vs less intensive: addl 15% RRR ❤️‍🔥 high intensity statin w/⬇️50mg/dL achieved = 28% RRR MACE 3/ <a href="https://med-mastodon.com/tags/llt" class="mention hashtag" rel="tag">#llt</a>

Viet Le, MPAS PA-C FACC FAHAtrying to understand why another provider told a young MI <55 yrs of age pt to stop their statin+eze and “just go with repatha, because it works better”.Fourier and Odyssey were incremental add-on tx to baseline statin, ADDing RRR of 15%. <a href="https://link.springer.com/article/10.1007/s40119-020-00163-w" target="_blank" rel="nofollow noopener noreferrer" translate="no">https://link.springer.com/article/10.1007/s40119-020-00163-w</a> <a href="https://med-mastodon.com/tags/llt" class="mention hashtag" rel="tag">#llt</a>

Viet Le, MPAS PA-C FACC FAHA<a href="https://med-mastodon.com/tags/PAD" class="mention hashtag" rel="tag">#PAD</a> - the forgotten <a href="https://med-mastodon.com/tags/ASCVD" class="mention hashtag" rel="tag">#ASCVD</a> component.🦵🏾MI/CVA events higher in PAD than in prior MI/CVA pts!!!! 🦵🏾Low use of statins/other LLT in PAD 👀😮 🦵🏾<a href="https://med-mastodon.com/tags/LLT" class="mention hashtag" rel="tag">#LLT</a> effective in PAD: statinize!<a href="https://med-mastodon.com/tags/acc23" class="mention hashtag" rel="tag">#acc23</a>

Viet Le, MPAS PA-C FACC FAHAIn an era of increased awareness surrounding <a href="https://med-mastodon.com/tags/APOB" class="mention hashtag" rel="tag">#APOB</a>, are we measuring this more and how does is relate to LDL-C? @ldjande3 leading out on @Intermountain data. <a href="https://med-mastodon.com/tags/acc23" class="mention hashtag" rel="tag">#acc23</a> <a href="https://med-mastodon.com/tags/llt" class="mention hashtag" rel="tag">#llt</a> @KirkKnowlton

Viet Le, MPAS PA-C FACC FAHAFantastic work by my colleague, 2nd year internal medicine resident Dr Stephanie Skove - Complex Cases <a href="https://med-mastodon.com/tags/CvPrev" class="mention hashtag" rel="tag">#CvPrev</a> <a href="https://med-mastodon.com/tags/LLT" class="mention hashtag" rel="tag">#LLT</a> Why we <a href="https://med-mastodon.com/tags/acc23" class="mention hashtag" rel="tag">#acc23</a> present, discuss, learn

Viet Le, MPAS PA-C FACC FAHA<a href="https://med-mastodon.com/tags/clearoutcomes" class="mention hashtag" rel="tag">#clearoutcomes</a> 🫀subgroups - yay benefit in women 🫀benefit seen in 1° 👀👍🏾 as well as 2° 🫀benefit in diabetes 🙌🏾🙌🏾Important CVOT adding <a href="https://med-mastodon.com/tags/BempedoicAcid" class="mention hashtag" rel="tag">#BempedoicAcid</a> into the hall of MACE reducing <a href="https://med-mastodon.com/tags/LLT" class="mention hashtag" rel="tag">#LLT</a>. <a href="https://med-mastodon.com/tags/acc23" class="mention hashtag" rel="tag">#acc23</a> <a href="https://med-mastodon.com/tags/HeartPA" class="mention hashtag" rel="tag">#HeartPA</a> <a href="https://med-mastodon.com/tags/PhysicianAssociate" class="mention hashtag" rel="tag">#PhysicianAssociate</a>

Viet Le, MPAS PA-C FACC FAHAHere, pt had a greater effect than anticipated (~45% reduction). Jumping to 80 mg (skipping 2 titrations) may only reduce an additional 18%.Meanwhile, adding ezetimibe 10 mg could potentially drop LDL-C by 20% w/o risk of statin myalgia.<a href="https://med-mastodon.com/tags/LLT" class="mention hashtag" rel="tag">#LLT</a> <a href="https://academic.oup.com/eurheartj/advance-article-abstract/doi/10.1093/eurheartj/ehac709/6931821?redirectedFrom=fulltext&login=false" target="_blank" rel="nofollow noopener noreferrer" translate="no">https://academic.oup.com/eurheartj/advance-article-abstract/doi/10.1093/eurheartj/ehac709/6931821?redirectedFrom=fulltext&login=false</a>

Viet Le, MPAS PA-C FACC FAHAAdding to @SABOURETCardio <a href="https://med-mastodon.com/tags/LLT" class="mention hashtag" rel="tag">#LLT</a> posts - Important to recognize even low(er) doses of statins have a great upfront reduction in LDL-C. Pt w/hx of statin intolerance and LDL-C 202 mg/dL, on reinitiation (atorva 10 mg), had f/u LDL-C, 110 mg/dL. <a href="https://med-mastodon.com/tags/PhysicianAssociate" class="mention hashtag" rel="tag">#PhysicianAssociate</a> <a href="https://med-mastodon.com/tags/RuleOf6s" class="mention hashtag" rel="tag">#RuleOf6s</a>

Viet Le, MPAS PA-C FACC FAHAFeel free to drop in this evening, as we discuss Lipid Guideline Updates and New Therapeutics. Reach out to Riley at rroberge@heartoneaz.com for the zoom link and password. <a href="https://med-mastodon.com/tags/LLT" class="mention hashtag" rel="tag">#LLT</a> <a href="https://med-mastodon.com/tags/PA" class="mention hashtag" rel="tag">#PA</a> <a href="https://med-mastodon.com/tags/PhysicianAssociate" class="mention hashtag" rel="tag">#PhysicianAssociate</a> <a href="https://med-mastodon.com/tags/HeartPA" class="mention hashtag" rel="tag">#HeartPA</a> <a href="https://med-mastodon.com/tags/Cardiology" class="mention hashtag" rel="tag">#Cardiology</a> <a href="https://med-mastodon.com/tags/PreventiveCardiology" class="mention hashtag" rel="tag">#PreventiveCardiology</a> @APAC_Car…<a href="https://lnkd.in/gEWhkzK5" target="_blank" rel="nofollow noopener noreferrer" translate="no">https://lnkd.in/gEWhkzK5</a>

Viet Le, MPAS PA-C FACC FAHAYounger woman (<50) with CABG following prior stent. FH+Baseline LDL-C >190 Lp(a) >200 nmol/LRosuvastatin 40 mg Praluent 150 mg/mLNow, LDL-C <30 mg/dL😍<a href="https://med-mastodon.com/tags/knowfh" class="mention hashtag" rel="tag">#knowfh</a> <a href="https://med-mastodon.com/tags/PhysicianAssociate" class="mention hashtag" rel="tag">#PhysicianAssociate</a> <a href="https://med-mastodon.com/tags/cvlipids" class="mention hashtag" rel="tag">#cvlipids</a> <a href="https://med-mastodon.com/tags/llt" class="mention hashtag" rel="tag">#llt</a> @KAWilemon

Viet Le, MPAS PA-C FACC FAHAReviewing <a href="https://med-mastodon.com/tags/AHA22" class="mention hashtag" rel="tag">#AHA22</a> on demand. @kewatson, thank you for your wonderful discussion on the PROMINENT trial1) fibrates in the statin era, do not lower CV risk 2) fibrates do lower trigs, consider for pancreatitis risk 3) room for NAFLD/NASH? 🤔 <a href="https://med-mastodon.com/tags/CardioTwitter" class="mention hashtag" rel="tag">#CardioTwitter</a> <a href="https://med-mastodon.com/tags/LLT" class="mention hashtag" rel="tag">#LLT</a>

Viet Le, MPAS PA-C FACC FAHAHonored to review lipid guidelines and the multitude of new/novel therapeutics for <a href="https://med-mastodon.com/tags/LLT" class="mention hashtag" rel="tag">#LLT</a>. Thank you HEART ONE ASSOCIATES LLC. <a href="https://med-mastodon.com/tags/CardioTwitter" class="mention hashtag" rel="tag">#CardioTwitter</a> <a href="https://med-mastodon.com/tags/PhysicianAssociates" class="mention hashtag" rel="tag">#PhysicianAssociates</a> <a href="https://med-mastodon.com/tags/ACCCVT" class="mention hashtag" rel="tag">#ACCCVT</a> <a href="https://med-mastodon.com/tags/NursePractitioners" class="mention hashtag" rel="tag">#NursePractitioners</a> @APAC_Cardiology Follow the link in the flyer:…<a href="https://lnkd.in/gfWNZTzT" target="_blank" rel="nofollow noopener noreferrer" translate="no">https://lnkd.in/gfWNZTzT</a>

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