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#hepatoblastoma

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KidsLiverHub<p><a href="https://med-mastodon.com/tags/hepatoblastoma" class="mention hashtag" rel="tag">#<span>hepatoblastoma</span></a> <a href="https://med-mastodon.com/tags/livercancer" class="mention hashtag" rel="tag">#<span>livercancer</span></a> <a href="https://med-mastodon.com/tags/kidsliverhub" class="mention hashtag" rel="tag">#<span>kidsliverhub</span></a> <a href="https://med-mastodon.com/tags/awareness" class="mention hashtag" rel="tag">#<span>awareness</span></a></p>
Arjan Boltjes<p>" Instead, <a href="https://mastodon.social/tags/Hepatoblastoma" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Hepatoblastoma</span></a> <a href="https://mastodon.social/tags/tumors" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>tumors</span></a> contain a large suppressive <a href="https://mastodon.social/tags/myeloid" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>myeloid</span></a> compartment which poses opportunities for targeting. Specifically, therapeutic antibodies<br>targeting the <a href="https://mastodon.social/tags/tumor" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>tumor</span></a> antigen <a href="https://mastodon.social/tags/GPC3" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>GPC3</span></a> to induce ADCP by <a href="https://mastodon.social/tags/macrophages" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>macrophages</span></a>, in combination with myeloid<br><a href="https://mastodon.social/tags/ImmuneCheckpointBlockade" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>ImmuneCheckpointBlockade</span></a> (<a href="https://mastodon.social/tags/CD47" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>CD47</span></a>/SIRPa, or VISTA) could be a feasible strategy to explore in future studies"</p><p>Krijgsman et al. from Vercoulen lab in the <a href="https://mastodon.social/tags/UMCUtrecht" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>UMCUtrecht</span></a>, on <a href="https://mastodon.social/tags/bioRXiv" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>bioRXiv</span></a>:<br><a href="https://www.biorxiv.org/content/10.1101/2023.06.28.546852v1" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">biorxiv.org/content/10.1101/20</span><span class="invisible">23.06.28.546852v1</span></a></p><p><a href="https://mastodon.social/tags/scRNAseq" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>scRNAseq</span></a> <a href="https://mastodon.social/tags/spatial" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>spatial</span></a> <a href="https://mastodon.social/tags/CyTOF" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>CyTOF</span></a> <a href="https://mastodon.social/tags/immunology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>immunology</span></a></p>
MarcusMuench<p>My colleagues and I performed a study looking for molecules on the surface of <a href="https://sfba.social/tags/liver" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>liver</span></a> cells during <a href="https://sfba.social/tags/prenatal" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>prenatal</span></a> development. Before birth, the liver contains heptoblasts, immature progenitors that can make hepatocytes and cholangiocyte (biliary cells). We found that these cells express a molecule know as CD203c. We also showed that a some <a href="https://sfba.social/tags/cancer" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cancer</span></a> cells found in <a href="https://sfba.social/tags/pediatric" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>pediatric</span></a> <a href="https://sfba.social/tags/hepatoblastoma" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>hepatoblastoma</span></a> also express CD203c. </p><p><a href="https://sfba.social/tags/CancerResearch" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>CancerResearch</span></a> <a href="https://sfba.social/tags/ScienceSavesLives" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>ScienceSavesLives</span></a> <a href="https://sfba.social/tags/medicine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>medicine</span></a></p>
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