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Giuseppe MichieliA <a href="https://mstdn.science/tags/human" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#human</a>-infecting <a href="https://mstdn.science/tags/H10N5" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H10N5</a> avian <a href="https://mstdn.science/tags/influenza" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#influenza</a> virus: <a href="https://mstdn.science/tags/clinical" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#clinical</a> features, virus <a href="https://mstdn.science/tags/reassortment" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#reassortment</a>, <a href="https://mstdn.science/tags/receptor" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#receptor</a>-binding affinity, and possible <a href="https://mstdn.science/tags/transmission" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#transmission</a> routes, <a href="https://etidiohnew.blogspot.com/2025/03/a-human-infecting-h10n5-avian-influenza.html" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://etidiohnew.blogspot.com/2025/03/a-human-infecting-h10n5-avian-influenza.html</a>

Giuseppe MichieliNorth <a href="https://mstdn.science/tags/American" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#American</a>-Origin <a href="https://mstdn.science/tags/Influenza" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Influenza</a> A (<a href="https://mstdn.science/tags/H10" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H10</a>) viruses in Eurasian Wild <a href="https://mstdn.science/tags/Birds" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Birds</a> (2022–2024): Implications for the Emergence of Human <a href="https://mstdn.science/tags/H10N5" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H10N5</a> Virus, <a href="https://etidiohnew.blogspot.com/2025/02/north-american-origin-influenza-h10.html" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://etidiohnew.blogspot.com/2025/02/north-american-origin-influenza-h10.html</a>

Giuseppe Michieli<a href="https://mstdn.science/tags/Gene" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Gene</a> flow and its sporadic <a href="https://mstdn.science/tags/spillover" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#spillover</a>: <a href="https://mstdn.science/tags/H10" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H10</a> and <a href="https://mstdn.science/tags/N5" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#N5</a> avian <a href="https://mstdn.science/tags/influenza" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#influenza</a> viruses from wild <a href="https://mstdn.science/tags/birds" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#birds</a> and the <a href="https://mstdn.science/tags/H10N5" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H10N5</a> <a href="https://mstdn.science/tags/human" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#human</a> cases in <a href="https://mstdn.science/tags/China" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#China</a>, <a href="https://etidiohnew.blogspot.com/2024/12/gene-flow-and-its-sporadic-spillover.html" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://etidiohnew.blogspot.com/2024/12/gene-flow-and-its-sporadic-spillover.html</a>

Giuseppe Michieli<a href="https://mstdn.science/tags/Epidemiology" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Epidemiology</a> and <a href="https://mstdn.science/tags/evolution" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#evolution</a> of <a href="https://mstdn.science/tags/human" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#human</a>-origin <a href="https://mstdn.science/tags/H10N5" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H10N5</a> <a href="https://mstdn.science/tags/influenza" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#influenza</a> virusSource: One Health, AbstractH10 subtype avian influenza viruses were endemic in wild and domestic avian species worldwide. Strikingly, it frequently crossed the species barrier to infect mammalian hosts. Human infection with H10N3 and H10N8 were reported previously. Recently, a 63-year-old woman from Anhui province of China who died from a mixed infection of H3N2 and H10N5…<a href="https://etidioh.wordpress.com/2024/10/09/epidemiology-and-evolution-of-human-origin-h10n5-influenza-virus/" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://etidioh.wordpress.com/2024/10/09/epidemiology-and-evolution-of-human-origin-h10n5-influenza-virus/</a>

Giuseppe Michieli''The HA <a href="https://mstdn.science/tags/genes" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#genes</a> were part of the <a href="https://mstdn.science/tags/American" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#American</a> <a href="https://mstdn.science/tags/lineage" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#lineage</a> of <a href="https://mstdn.science/tags/H10N5" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H10N5</a>, showing 95.2% homology with A/Anser albifrons/South Korea/22JN-163-1/2022 (<a href="https://mstdn.science/tags/H10N7" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H10N7</a>) (GenBank: OQ296824.1). Conversely, the NA genes belonged to the <a href="https://mstdn.science/tags/Eurasian" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Eurasian</a> lineage, with the highest homology (97.82%) to A/Spot-billed duck (Anas poecilohyncha)/Korea/KNU17/2022 (<a href="https://mstdn.science/tags/H6N5" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H6N5</a>) (GenBank: OR674089.1) ''

Giuseppe MichieliOutbreak Reports: A Retrospective <a href="https://mstdn.science/tags/Investigation" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Investigation</a> of a Case of Dual <a href="https://mstdn.science/tags/Infection" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Infection</a> by <a href="https://mstdn.science/tags/Avian" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Avian</a>-Origin <a href="https://mstdn.science/tags/Influenza" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Influenza</a> A (<a href="https://mstdn.science/tags/H10N5" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H10N5</a>) and Seasonal Influenza A (<a href="https://mstdn.science/tags/H3N2" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H3N2</a>) Viruses — <a href="https://mstdn.science/tags/Anhui" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Anhui</a> Province, <a href="https://mstdn.science/tags/China" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#China</a>, Dec '23–Jan '24, CCDC: <a href="https://weekly.chinacdc.cn/en/article/doi/10.46234/ccdcw2024.106" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://weekly.chinacdc.cn/en/article/doi/10.46234/ccdcw2024.106</a> This report documents the first human case of co-infection with avian-origin H10N5 and seasonal H3N2 influenza viruses. Epidemiological investigations identified H10N5 in environmental samples linked to the patient, but no transmission to close contacts occurred.

Giuseppe MichieliAvian <a href="https://mstdn.science/tags/Influenza" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Influenza</a> Virus and Avian <a href="https://mstdn.science/tags/Paramyxoviruses" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Paramyxoviruses</a> in Wild <a href="https://mstdn.science/tags/Waterfowl" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Waterfowl</a> of the Western Coast of the <a href="https://mstdn.science/tags/Caspian" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Caspian</a> Sea (2017–2020), Viruses: <a href="https://www.mdpi.com/1999-4915/16/4/598" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.mdpi.com/1999-4915/16/4/598</a> The following subtypes were determined and whole-genome nucleotide sequences of the isolated strains were obtained: <a href="https://mstdn.science/tags/H1N1" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H1N1</a> (n = 2), <a href="https://mstdn.science/tags/H3N8" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H3N8</a> (n = 8), <a href="https://mstdn.science/tags/H4N6" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H4N6</a> (n = 2), <a href="https://mstdn.science/tags/H7N3" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H7N3</a> (n = 2), <a href="https://mstdn.science/tags/H8N4" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H8N4</a> (n = 1), <a href="https://mstdn.science/tags/H10N5" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H10N5</a> (n = 1), and <a href="https://mstdn.science/tags/H12N5" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H12N5</a> (n = 1). No high pathogenicity influenza virus H5 subtype was detected.

Giuseppe Michieli<a href="https://mstdn.science/tags/Influenza" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Influenza</a> at the <a href="https://mstdn.science/tags/human" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#human</a>-animal <a href="https://mstdn.science/tags/interface" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#interface</a> - <a href="https://mstdn.science/tags/Summary" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Summary</a> and <a href="https://mstdn.science/tags/risk" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#risk</a> <a href="https://mstdn.science/tags/assessment" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#assessment</a>, from 22 December 2023 to 26 February 2024, WHO: <a href="https://www.who.int/publications/m/item/influenza-at-the-human-animal-interface-summary-and-assessment-26--february-2024" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.who.int/publications/m/item/influenza-at-the-human-animal-interface-summary-and-assessment-26--february-2024</a> From 22 Dec 23 to 26 Feb 24, 5 cases of infection w flu <a href="https://mstdn.science/tags/H5N1" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H5N1</a>, 1 case of infection w an <a href="https://mstdn.science/tags/H5N6" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H5N6</a> virus, 1 infection w an <a href="https://mstdn.science/tags/H9N2" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H9N2</a> virus, 1 case of infection with an <a href="https://mstdn.science/tags/H10N5" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H10N5</a> virus, & 2 cases of infection with <a href="https://mstdn.science/tags/H1N1" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H1N1</a> <a href="https://mstdn.science/tags/variant" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#variant</a> viruses were reported officially. Additionally, 1 case of infection with an <a href="https://mstdn.science/tags/H9N2" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H9N2</a> <a href="https://mstdn.science/tags/variant" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#variant</a> virus was detected.

Giuseppe MichieliZoonotic <a href="https://mstdn.science/tags/influenza" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#influenza</a>: During period from 26 Sept 23 to 19 Feb 24, sporadic <a href="https://mstdn.science/tags/zoonotic" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#zoonotic</a> influenza cases were reported following exposure to infected birds & swine in most cases. 2 cases of <a href="https://mstdn.science/tags/H5N6" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H5N6</a>, 4 of <a href="https://mstdn.science/tags/H9N2" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H9N2</a> & 1 of <a href="https://mstdn.science/tags/H10N5" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H10N5</a> were reported in <a href="https://mstdn.science/tags/China" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#China</a> & 8 cases of <a href="https://mstdn.science/tags/H5N1" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H5N1</a> were reported in <a href="https://mstdn.science/tags/Cambodia" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Cambodia</a>. Single cases of <a href="https://mstdn.science/tags/H1N1v" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H1N1v</a> were reported in <a href="https://mstdn.science/tags/Brazil" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Brazil</a>, <a href="https://mstdn.science/tags/Spain" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Spain</a> & <a href="https://mstdn.science/tags/Switzerland" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Switzerland</a> in this period. 1 case of <a href="https://mstdn.science/tags/H1N2v" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H1N2v</a> was reported in the <a href="https://mstdn.science/tags/UK" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#UK</a>. <a href="https://cdn.who.int/media/docs/default-source/influenza/who-influenza-recommendations/vcm-northern-hemisphere-recommendation-2024-2025/recommended-composition-of-influenza-virus-vaccines-for-use-in-the-2024-2025-northern-hemisphere-influenza-season.pdf?sfvrsn=2e9d2194_7&download=true" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://cdn.who.int/media/docs/default-source/influenza/who-influenza-recommendations/vcm-northern-hemisphere-recommendation-2024-2025/recommended-composition-of-influenza-virus-vaccines-for-use-in-the-2024-2025-northern-hemisphere-influenza-season.pdf?sfvrsn=2e9d2194_7&download=true</a>

Giuseppe Michieli<a href="https://mstdn.science/tags/WHO" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#WHO</a> (13 February 2024). Disease <a href="https://mstdn.science/tags/Outbreak" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Outbreak</a> <a href="https://mstdn.science/tags/News" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#News</a>; Avian <a href="https://mstdn.science/tags/Influenza" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Influenza</a> A(<a href="https://mstdn.science/tags/H10N5" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H10N5</a>) and Influenza A(<a href="https://mstdn.science/tags/H3N2" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H3N2</a>) <a href="https://mstdn.science/tags/coinfection" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#coinfection</a> - <a href="https://mstdn.science/tags/China" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#China</a>. Available at <a href="https://www.who.int/emergencies/disease-outbreak-news/item/2023-DON504" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.who.int/emergencies/disease-outbreak-news/item/2023-DON504</a> -- 1 confirmed case of <a href="https://mstdn.science/tags/human" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#human</a> <a href="https://mstdn.science/tags/coinfection" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#coinfection</a> with <a href="https://mstdn.science/tags/H10N5" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H10N5</a> virus & seasonal influenza A(<a href="https://mstdn.science/tags/H3N2" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H3N2</a>). This is 1rst case of <a href="https://mstdn.science/tags/human" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#human</a> infection with avian influenza H10N5 reported globally. Case occurred in a female farmer over 60 yrs, with chronic comorbidities, from Anhui Province. Onset on 30 Nov 23 & passed away on 16 Dec 2023.

Giuseppe Michieli<a href="https://mstdn.science/tags/China" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#China</a> reported one <a href="https://mstdn.science/tags/human" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#human</a> <a href="https://mstdn.science/tags/infection" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#infection</a> with Avian <a href="https://mstdn.science/tags/influenza" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#influenza</a> A(<a href="https://mstdn.science/tags/H10N5" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H10N5</a>) in <a href="https://mstdn.science/tags/Zhejiang" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#Zhejiang</a> Province: a 63-year-old woman, with onset on November 30, 2023, was co-infected with influenza A(<a href="https://mstdn.science/tags/H3N2" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H3N2</a>). <a href="https://mstdn.science/tags/HK" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#HK</a> CHP: <a href="https://www.chp.gov.hk/files/pdf/2024_avian_influenza_report_vol20_wk05.pdf" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.chp.gov.hk/files/pdf/2024_avian_influenza_report_vol20_wk05.pdf</a>

Giuseppe Michieli<a href="https://mstdn.science/tags/HK" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#HK</a> CHP closely monitors <a href="https://mstdn.science/tags/human" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#human</a> case co-infected with avian <a href="https://mstdn.science/tags/influenza" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#influenza</a> A(<a href="https://mstdn.science/tags/H10N5" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H10N5</a>) and influenza A(<a href="https://mstdn.science/tags/H3N2" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#H3N2</a>) on Mainland {<a href="https://mstdn.science/tags/China" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#China</a>}, <a href="https://www.info.gov.hk/gia/general/202401/31/P2024013100657.htm?fontSize=1" rel="nofollow noopener noreferrer" translate="no" target="_blank">https://www.info.gov.hk/gia/general/202401/31/P2024013100657.htm?fontSize=1</a>-- a 63-year-old female with underlying medical problems, who developed symptoms on Nov 30 last year and was admitted for treatment on December 2. She passed away on December 16. Her relevant close contacts did not show any abnormalities during the medical surveillance period.

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