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#dosing

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Tim Street<p>GLP1-RAs in Type 1 Diabetes: Dosing and Pharmacokinetics<br>As we discussed in the previous article, people are starting to use incretins as an adjunct therapy in the treatment of type 1 diabetes. All off label, of course.</p><p>Anyone familiar with these drugs will know that they are indicated to be injected once a wee<br><a href="https://www.diabettech.com/glp1-ra/glp1-ras-in-type-1-diabetes-dosing-and-pharmacokinetics/" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">diabettech.com/glp1-ra/glp1-ra</span><span class="invisible">s-in-type-1-diabetes-dosing-and-pharmacokinetics/</span></a><br><a href="https://mastodonapp.uk/tags/GLP1RA" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>GLP1RA</span></a> <a href="https://mastodonapp.uk/tags/Dosing" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Dosing</span></a> <a href="https://mastodonapp.uk/tags/Halflife" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Halflife</span></a> <a href="https://mastodonapp.uk/tags/Mounjaro" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Mounjaro</span></a> <a href="https://mastodonapp.uk/tags/Semaglutide" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Semaglutide</span></a> <a href="https://mastodonapp.uk/tags/Tirzepatide" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Tirzepatide</span></a> <a href="https://mastodonapp.uk/tags/variability" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>variability</span></a> <a href="https://mastodonapp.uk/tags/WeGovy" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>WeGovy</span></a></p>
Giuseppe Michieli<p>Influence of <a href="https://mstdn.science/tags/mRNA" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>mRNA</span></a> <a href="https://mstdn.science/tags/Covid19" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Covid19</span></a> <a href="https://mstdn.science/tags/vaccine" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>vaccine</span></a> <a href="https://mstdn.science/tags/dosing" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>dosing</span></a> interval on <a href="https://mstdn.science/tags/risk" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>risk</span></a> of <a href="https://mstdn.science/tags/myocarditis" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>myocarditis</span></a>, Nat Commun.: <a href="https://www.nature.com/articles/s41467-024-52038-6" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://www.</span><span class="ellipsis">nature.com/articles/s41467-024</span><span class="invisible">-52038-6</span></a> </p><p>Here we show that longer intervals between each consecutive dose, including <a href="https://mstdn.science/tags/booster" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>booster</span></a>, may decrease occurrence of vaccine-associated myocarditis by up to a factor of 4, especially under age 50. These results suggest that a minimum 6-month interval might be required when scheduling additional booster vaccination.</p>
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