Say hi to our new project INTERCEPT, which will develop biomarkers that can identify people with a high risk of developing #CrohnsDisease. 
A further trial will then evaluate whether full onset of the disease can be prevented.
More: https://europa.eu/!3GFHbF
#IHITransformingHealth #HealthResearch #HorizonEU #HorizonEurope #EUResearch
This brought to you by learning today that I'll have four weeks to potentially find and see a new care team, get them to issue a new script to a new pharmacy benefit provider, get pre-approval for Skyrizi from said pharmacy provider, and get the med delivered by a new specialty pharmacy.
But I can't even find out yet if my doctors are in network with the new plan or if the benefits will even consider covering Skyrizi. So that's exciting.
It's #skyrizi injection day.
I missed the morning appointment on my calendar and just happened to have a mental spark of "isn't that supposed to happen today?"
So I clearly need to do something better with my reminders/appointments/thingamajigs.
Anyway, it's out and coming to room temperature.
Still better than having to drive 2 hours for a 3 hour IV infusion, then 2 hours back (and after Benadryl!) like I was doing for Inflectra.
Aren't bodies fun?
Wow!
Linking a particular bacteria of the gut microbiome in a chain that could potentially be a source of major depression. Follow up research could also show how environmental contaminants combined with the metabolism of the gut microbiome could be linked to autoimmune and other conditions.
Science is amazing!
Can't wait to see where this drives other future research and, eventually, treatments.
https://hms.harvard.edu/news/drawing-line-gut-microbiome-inflammation-depression
Skyrizi injection done.
A five minute process is so much easier than a three hour infusion. Or the one hour infusion at a facility two hours away that the initial Skyrizi startup process involved.
If you are someone who relies on a prescription #medication... my advice is to start hoarding a backup supply. If there's overlap in your refill window or if you can safely skip a pill from time to time... it's a good idea to build up a stash for during times of unrest or supply chain problems.
Rotate the backup supply with fresh ones so they don't expire.
I had to dip into my backups during Covid & it really eased my anxiety about it.
I know that as a "health conscious adult" I'm not supposed to say this.... But I *HATE* leafy green vegetables. I also, as someone with #CrohnsDisease don't digest it well. My husband is also having some not-yet-diagnosed stomach problems.
So I bought this bad boy. 
I am entering the world of green #smoothie making.
As a veteran of colonoscopies, I’ve actually lost count, tomorrow’s is my 7th I think, this has to be the worst prep regime I’ve had yet. Usual drink of a litre of vile stuff 18:00-19:00 but the second lot is at 05:00-06:00 before the procedure at 08:30 - and I have to be in a taxi 06:15 to get there for 07:00. Not going to happen that. Will be later than 07:00 but last time there was a long time sitting about waiting anyway.
This study by Mengyuan Zhou et al. investigated the feasibility of intestinal ultrasound for the semiquantitative analysis of creeping fat.
This #EuropeanRadiology study aimed to externally validate a scoring system to monitor the response to medical and surgical treatment regimens in perianal fistulising #CrohnsDisease. Kim J. Beek et al. found the MAGNIFI-CD index to be a responsive and reliable #MRI scoring instrument for treatment monitoring in Crohn's.
Working out after immunobiological infusion day is """"fun""""
#crohnsDisease #chronicIllness
Educational Review: Imaging findings of thoracic manifestations of #CrohnsDisease and ulcerative colitis. (Quentin Cassius De Linval et al.)
Shankar Kumar et al. evaluated the feasibility of volumetric measurement of terminal ileal #CrohnsDisease (CD) on MRE compared to endoscopy and simplified magnetic resonance index of activity (sMARIA), taking a step towards developing an obejctive and responsive MRE-based volumetric score for CD.
@rood
As I suspected. Thanks. I’ve had #crohnsDisease since I was a kid. Don’t know that I’ve ever had one of those.
My wife encouraged me to write this for #DisabilityPrideMonth which ends today. It definitely feels odd to write this, but here it is.
"If you see someone use the disabled toilet (or any toilet) just... mind your own business. You don't need to try and measure their disability, or guess their gender."
https://blog.brettsheffield.com/not-all-disability-is-visible
New:
Systemic antibody responses against gut microbiota flagellins implicate shared & divergent immune reactivity in Crohn’s disease & #ChronicFatigueSyndrome
Free:
https://microbiomejournal.biomedcentral.com/articles/10.1186/s40168-024-01858-1
2-minute video abstract at link explains it better
#MEcfs #CFS #PwME #CrohnsDisease @mecfs
#MyalgicEncephalomyelitis #ChronicFatigueSyndrome #Crohns @crohns
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In this #InsightsIntoImaging article, Mengchen Zhang et al. utilized #radiomics models to improve the diagnostic accuracy of radiologists characterizing intestinal fibrosis in #CrohnsDisease patients.
A CAUSE OF INFLAMMATORY BOWEL DISEASE FOUND
Mastodon Post
BBC
Major cause of inflammatory bowel disease found
1 day ago
James Gallagher,Health and science correspondent
https://www.bbc.com/news/articles/c1wwdd6v2wjo
This is very serious business. Going on memory, my barber needed surgery because of long-term use of medication for Crohn's disease. He died of some complication from the surgery. He had the surgery, he seemed to be recovering well, and then, quite suddenly, he was gone.
:
#crohnsandcolitis #crohnsdisease #cytokines #franciscrickinstitute #inflammatoryboweldisease #inflammatorycolitis #jamesgallagher #jameslee #macrophages #medicalscience #medicalsciencenews #ruthwakeman #sciencenews #ulcerativecolitis #universitycollegelondon
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