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#Colistin

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Public
Infektionsforschung (HZI)

Das #Antibiotikum #Colistin ermöglicht zwar die Behandlung von schweren Infektionen mit resistenten Bakterien, kann allerdings die Nieren schädigen. Forschende der Abteilung „Chemische Biologie“ unter der Leitung von Mark Brönstrup haben eine Technik entwickelt, um diese Nebenwirkung zu umgehen. helmholtz-hzi.de/media-center/

www.helmholtz-hzi.deChemischer Trick aktiviert Antibiotikum direkt am ErregerHZI-Studie entwickelt Click-to-Release-Technik zur Vermeidung der stark nephrotoxischen Wirkung von Colistin
Public
Phys.org

Referenced link: medicalxpress.com/news/2023-04
Discuss on discu.eu/q/https://medicalxpre

Originally posted by Phys.org / @physorg_com: nitter.platypush.tech/medical_

RT by @physorg_com: #Colistin-resistant #E.coli gains resistance to innate human immunity @elife elifesciences.org/articles/843 medicalxpress.com/news/2023-04

medicalxpress.comColistin-resistant E. coli gains resistance to innate human immunityResearchers from the University of Oxford, U.K., have investigated the evolution of antibiotic resistance properties of antimicrobial peptides (AMPs). In the paper "The evolution of colistin resistance increases bacterial resistance to host antimicrobial peptides and virulence," published in eLife, researchers detail a disturbing discovery of how a specific type of antimicrobial agent, colistin, could be training E. coli and possibly other pathogens to evade the human immune system better.
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