Excited to showcase our work demonstrating the development & efficacy of a computational ontology platform that can elucidate biomolecular relationships & interactions.
Given that prior studies have identified an association between coronaviral infection and BALT formation, the platform was effective in showcasing the relationship between SARS-CoV-2 and BALT lymphoma development showing a literary relationship between serine proteases (SERPINE1) with heat shock proteins (HS90) and COVID-19, with aryl hydrocarbon (acting as this bridge between BALT lymphomas, transmembrane bound serine proteases, and SARS-CoV-2.
This platform can also provide genetic, proteomic, and clinical trials information that can effectively be deployed toward characterizing disease pathogenesis, even in rare hematological malignancies.
Thank you to Dr. Chandler Park, M.D., F.A.C.P. for your mentorship and to the great team of Samarth Sandeep & Kirk McGregor at If and Only If (Iff) Technologies that helped make this project possible.
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