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Appalling outbreak in the USA: contaminated bone grafts made by #Aziyo Biologics using cells from an 80-year-old man with apparent undiagnosed tuberculosis infected at least 87 patients, at least three of whom later died of TB. 
Regenerative medicine has vast promise, but also potential dangers.
PubMed Central (PMC)Nationwide tuberculosis outbreak in the USA linked to a bone graft product: an outbreak reportMycobacterium tuberculosis transmission through solid organ transplantation has been well described, but transmission through transplanted tissues is rare. We investigated a tuberculosis outbreak in the USA linked to a bone graft product containing live ...
BTW, this outbreak was recognized primarily due to the efforts of Dr. Marci Drees, who was a brilliant ID fellow at Tufts in my former life as an ID attending @HelenBranswell https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437057/
PubMed Central (PMC)Notes from the Field: Tuberculosis Outbreak Linked to a Contaminated Bone Graft Product Used in Spinal Surgery — Delaware, March–June 2021
