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Swapnil Hiremath :renal: MD

From Ed Fu et al - but not target trial emulation, this is a propensity score matched analysis

vs

Focusing on safety outcomes

journals.lww.com/cjasn/Abstrac in

Flozins =

More fracture

More LL amputations

More genital mycotoxins infections

But 1/

Figure 1. Number of events, incidence rates, incidence rate differences, and hazard ratios for safety outcomes, comparing SGLT2i versus GLP-1RA after 1:1 propensity score matching. CI = confidence interval; GLP-1RA = glucagon-like peptide-1 receptor agonist; HR = hazard ratio; PY = person-year; SGLT2i = sodium-glucose cotransporter-2 inhibitors; UTI = urinary tract infection.
Feb 24, 2023, 11:03 PM·Public·Toot!
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Swapnil Hiremath :renal: MD

No increase in DKA!

Why is that?

The LLA graph is impressive. (Also note this result would be similar to the BMJ bmj.com/content/363/bmj.k4365 which otherwise reported more DKA with flozins)

@mike_johansen @ChristosArgyrop @Kidney_boy @Bneuen

2/2

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